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3P5L
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BU of 3p5l by Molmil
Human Carbonic Anhydrase complexed with sodium 4-cyano-4-phenylpiperidine-1-carbodithioate
Descriptor: 4-cyano-4-phenylpiperidine-1-carbodithioic acid, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
Authors:Aggarwal, M, McKenna, R.
Deposit date:2010-10-08
Release date:2011-10-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.498 Å)
Cite:Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations.
Chem.Commun.(Camb.), 48, 2012
3OTM
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BU of 3otm by Molmil
Crystal structures of wild-type gamma-carbonic anhydrase from Methanosarcina thermophila
Descriptor: Carbonic anhydrase, ZINC ION
Authors:Domsic, J.F, Robbins, A.H, McKenna, R.
Deposit date:2010-09-13
Release date:2011-10-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of gamma-carbonic anhydrase mutants from Methanosarcina thermophila
To be Published
3OUP
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BU of 3oup by Molmil
Crystal structure of the gamma-carbonic anhydrase W19N mutant from Methanosarcina thermophila
Descriptor: Carbonic anhydrase, ZINC ION
Authors:Domsic, J.F, Robbins, A.H, McKenna, R.
Deposit date:2010-09-15
Release date:2011-10-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the gamma-carbonic anhydrase W19N mutant from Methanosarcina thermophila
To be Published
3OYS
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BU of 3oys by Molmil
Human Carbonic Anhydrase II complexed with 2-{[4-AMINO-3-(3-HYDROXYPROP-1-YN-1-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]METHYL}-5-METHYL-3-(2-METHYLPHENYL)QUINAZOLIN-4(3H)-ONE
Descriptor: 2-phenyl-N-(4-sulfamoylphenyl)acetamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
Authors:Aggarwal, M, McKenna, R.
Deposit date:2010-09-23
Release date:2011-08-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.538 Å)
Cite:Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV.
J.Med.Chem., 54, 2011
3OU9
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BU of 3ou9 by Molmil
Crystal structure of gamma-carbonic anhydrase W19F mutant from Methanosarcina thermophila
Descriptor: BICARBONATE ION, Carbonic anhydrase, ZINC ION
Authors:Domsic, J.F, Robbins, A.H, McKenna, R.
Deposit date:2010-09-14
Release date:2011-10-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of gamma-carbonic anhydrase W19F mutant from Methanosarcina thermophila
TO BE PUBLISHED
3OW5
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BU of 3ow5 by Molmil
Crystal structure of the Y200A mutant of gamma carbonic anhydrase from Methanosarcina thermophila
Descriptor: BICARBONATE ION, Carbonic anhydrase, FE (III) ION, ...
Authors:Domsic, J.F, Robbins, A.H, McKenna, R.
Deposit date:2010-09-17
Release date:2011-10-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal structure of the Y200A mutant of Methanosarcina thermophila
TO BE PUBLISHED
3PWE
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BU of 3pwe by Molmil
Crystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution
Descriptor: DNA polymerase III subunit beta
Authors:Marzahn, M.R, Robbins, A.H, McKenna, R, Bloom, L.B.
Deposit date:2010-12-08
Release date:2011-10-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:The E. coli clamp loader can actively pry open the beta-sliding clamp
J.Biol.Chem., 286, 2011
3QYK
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BU of 3qyk by Molmil
Human Carbonic Anhydrase II complexed with triple ring benzene sulfonamide inhibitor
Descriptor: 4-(7-methylpyrazolo[3',4':4,5]thiopyrano[2,3-b]pyridin-1(4H)-yl)benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
Authors:Aggarwal, M, McKenna, R.
Deposit date:2011-03-03
Release date:2012-03-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.469 Å)
Cite:Human Carbonic Anhydrase II complexed with triple ring benzene sulfonamide inhibitor
To be Published
3R17
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BU of 3r17 by Molmil
hCarbonic anhydrase II bound to N-(2-fluoro.4-sulfamoylphenyl)-2-(thiophen-2-yl) acetamide
Descriptor: Carbonic anhydrase 2, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Biswas, S, McKenna, R.
Deposit date:2011-03-09
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms.
Bioorg.Med.Chem., 19, 2011
1GFF
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BU of 1gff by Molmil
THE ATOMIC STRUCTURE OF THE DEGRADED PROCAPSID PARTICLE OF THE BACTERIOPHAGE G4: INDUCED STRUCTURAL CHANGES IN THE PRESENCE OF CALCIUM IONS AND FUNCTIONAL IMPLICATIONS
Descriptor: BACTERIOPHAGE G4 CAPSID PROTEINS GPF, GPG, GPJ
Authors:Rossmann, M.G.
Deposit date:1995-11-06
Release date:1996-04-03
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Atomic structure of the degraded procapsid particle of the bacteriophage G4: induced structural changes in the presence of calcium ions and functional implications.
J.Mol.Biol., 256, 1996
1AL0
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BU of 1al0 by Molmil
PROCAPSID OF BACTERIOPHAGE PHIX174
Descriptor: CAPSID PROTEIN GPF, SCAFFOLDING PROTEIN GPB, SCAFFOLDING PROTEIN GPD, ...
Authors:Rossmann, M.G, Dokland, T.
Deposit date:1997-06-06
Release date:1998-01-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of a viral procapsid with molecular scaffolding.
Nature, 389, 1997
1CD3
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BU of 1cd3 by Molmil
PROCAPSID OF BACTERIOPHAGE PHIX174
Descriptor: PROTEIN (CAPSID PROTEIN GPF), PROTEIN (SCAFFOLDING PROTEIN GPB), PROTEIN (SCAFFOLDING PROTEIN GPD), ...
Authors:Rossmann, M.G, Dokland, T.
Deposit date:1999-03-05
Release date:1999-04-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The role of scaffolding proteins in the assembly of the small, single-stranded DNA virus phiX174.
J.Mol.Biol., 288, 1999
7ASJ
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BU of 7asj by Molmil
Crystal structure for the complex of human carbonic anhydrase II and 3-(3-methyl-3-phenethylureido)benzenesulfonamide
Descriptor: 3-(3-methyl-3-phenethylureido)benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Angeli, A, Ferraroni, M.
Deposit date:2020-10-27
Release date:2021-11-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes.
J.Med.Chem., 65, 2022
5EGC
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BU of 5egc by Molmil
Structure of the Adeno-Associated Virus Serotype 1 sialic acid complex
Descriptor: Capsid protein, MAGNESIUM ION, N-acetyl-alpha-neuraminic acid
Authors:Huang, L.Y, Agbandje-McKenna, M.
Deposit date:2015-10-27
Release date:2016-03-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.011 Å)
Cite:Characterization of the Adeno-Associated Virus 1 and 6 Sialic Acid Binding Site.
J.Virol., 90, 2016
1C8E
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BU of 1c8e by Molmil
FELINE PANLEUKOPENIA VIRUS EMPTY CAPSID STRUCTURE
Descriptor: FELINE PANLEUKOPENIA VIRUS CAPSID
Authors:Rossmann, M.G, Simpson, A.A.
Deposit date:2000-05-05
Release date:2000-08-09
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Host range and variability of calcium binding by surface loops in the capsids of canine and feline parvoviruses.
J.Mol.Biol., 300, 2000
1C8F
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BU of 1c8f by Molmil
FELINE PANLEUKOPENIA VIRUS EMPTY CAPSID STRUCTURE
Descriptor: CALCIUM ION, FELINE PANLEUKOPENIA VIRUS CAPSID
Authors:Rossmann, M.G, Simpson, A.A.
Deposit date:2000-05-05
Release date:2000-08-09
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Host range and variability of calcium binding by surface loops in the capsids of canine and feline parvoviruses.
J.Mol.Biol., 300, 2000
1C8G
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BU of 1c8g by Molmil
FELINE PANLEUKOPENIA VIRUS EMPTY CAPSID STRUCTURE
Descriptor: CALCIUM ION, FELINE PANLEUKOPENIA VIRUS CAPSID
Authors:Rossmann, M.G, Simpson, A.A.
Deposit date:2000-05-05
Release date:2000-08-09
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Host range and variability of calcium binding by surface loops in the capsids of canine and feline parvoviruses.
J.Mol.Biol., 300, 2000
1C8H
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BU of 1c8h by Molmil
CANINE PARVOVIRUS STRAIN D EMPTY CAPSID STRUCTURE AT PH 5.5
Descriptor: CALCIUM ION, CANINE PARVOVIRUS CAPSID
Authors:Rossmann, M.G, Simpson, A.A.
Deposit date:2000-05-05
Release date:2000-08-09
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Host range and variability of calcium binding by surface loops in the capsids of canine and feline parvoviruses.
J.Mol.Biol., 300, 2000
1C8D
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BU of 1c8d by Molmil
CANINE PANLEUKOPENIA VIRUS EMPTY CAPSID STRUCTURE
Descriptor: CALCIUM ION, CANINE PARVOVIRUS CAPSID
Authors:Rossmann, M.G, Simpson, A.A.
Deposit date:2000-05-05
Release date:2000-08-09
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Host range and variability of calcium binding by surface loops in the capsids of canine and feline parvoviruses.
J.Mol.Biol., 300, 2000
1IJJ
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BU of 1ijj by Molmil
THE X-RAY CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN RABBIT SKELETAL MUSCLE ACTIN AND LATRUNCULIN A AT 2.85 A RESOLUTION
Descriptor: ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Vorobiev, S.M, Bubb, M.R, Almo, S.C.
Deposit date:2001-04-26
Release date:2002-04-15
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution
J.Biol.Chem., 277, 2002
8TXO
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BU of 8txo by Molmil
E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Aiyer, S, Shan, Z, Oh, J, Wang, D, Tan, Y.Z, Lyumkis, D.
Deposit date:2023-08-23
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Overcoming resolution attenuation during tilted cryo-EM data collection.
Nat Commun, 15, 2024
2AX2
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BU of 2ax2 by Molmil
Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II
Descriptor: Carbonic anhydrase II, ZINC ION
Authors:Budayova-Spano, M, Fisher, S.Z, Dauvergne, M.T, Silverman, D.N, Myles, D.A.A, McKenna, R.M.
Deposit date:2005-09-02
Release date:2006-01-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Production and X-ray crystallographic analysis of fully deuterated human carbonic anhydrase II.
Acta Crystallogr.,Sect.F, 62, 2006
4ZWI
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BU of 4zwi by Molmil
Surface Lysine Acetylated Human Carbonic Anhydrase II in Complex with a Sulfamate-Based Inhibitor
Descriptor: (6R)-1-O-acetyl-2,6-anhydro-6-{[4-(sulfamoyloxy)piperidin-1-yl]sulfonyl}-L-glucitol, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
Authors:Lomelino, C.L, Mahon, B.P, McKenna, M.
Deposit date:2015-05-19
Release date:2015-08-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Observed surface lysine acetylation of human carbonic anhydrase II expressed in Escherichia coli.
Protein Sci., 24, 2015
1MVM
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BU of 1mvm by Molmil
MVM(STRAIN I), COMPLEX(VIRAL COAT/DNA), VP2, PH=7.5, T=4 DEGREES C
Descriptor: DNA (5'-D(*CP*AP*AP*A)-3'), DNA (5'-D(*CP*CP*AP*CP*CP*CP*CP*AP*AP*CP*A)-3'), DNA (5'-D(P*A)-3'), ...
Authors:Llamas-Saiz, A.L, Agbandje-McKenna, M, Rossmann, M.G.
Deposit date:1996-06-21
Release date:1998-02-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure determination of minute virus of mice.
Acta Crystallogr.,Sect.D, 53, 1997
2FLE
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BU of 2fle by Molmil
Structural analysis of asymmetric inhibitor bound to the HIV-1 Protease V82A mutant
Descriptor: (2S,2'S)-N,N'-[(2S,3S,4S,5S)-1-CYCLOHEXYL-3,4-DIHYDROXY-6-PHENYLHEXANE-2,5-DIYL]BIS[3-METHYL-2-({[METHYL(PYRIDIN-2-YLMETHYL)AMINO]CARBONYL}AMINO)BUTANAMIDE], GLYCEROL, pol protein
Authors:Clemente, J.C, Robbins, A, Dunn, B.M, Sussman, F.
Deposit date:2006-01-05
Release date:2007-01-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation.
J.Med.Chem., 51, 2008

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