4Z0E
 
 | | Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038TRN] peptide | | 分子名称: | Apical membrane antigen 1, Rhoptry neck protein 2 | | 著者 | Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J. | | 登録日 | 2015-03-26 | | 公開日 | 2016-08-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
|
|
4Z0F
 | | Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038(6CW)] peptide | | 分子名称: | Apical membrane antigen 1, Rhoptry neck protein 2 | | 著者 | Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J. | | 登録日 | 2015-03-26 | | 公開日 | 2016-08-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
|
|
4Z0D
 | | Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038Trp] peptide | | 分子名称: | Apical membrane antigen 1, Rhoptry neck protein 2 | | 著者 | Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J. | | 登録日 | 2015-03-26 | | 公開日 | 2016-08-03 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
|
|
4ZQT
 | | Crystal structure of PfA-M1 with virtual ligand inhibitor | | 分子名称: | (2R)-2-{[(R)-[(R)-amino(phenyl)methyl](hydroxy)phosphoryl]methyl}-4-methylpentanoic acid, GLYCEROL, M1 family aminopeptidase, ... | | 著者 | Ruggeri, C, Drinkwater, N, McGowan, S. | | 登録日 | 2015-05-11 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | | 主引用文献 | Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening.
Plos One, 10, 2015
|
|
4Z09
 | | Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Thr2040Ala] peptide | | 分子名称: | Apical membrane antigen 1, GLYCEROL, Rhoptry neck protein 2 | | 著者 | Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J. | | 登録日 | 2015-03-26 | | 公開日 | 2016-08-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
|
|
5CBM
 | | Crystal structure of PfA-M17 with virtual ligand inhibitor | | 分子名称: | (2S)-2-{[(R)-[(R)-amino(phenyl)methyl](hydroxy)phosphoryl]methyl}-4-methylpentanoic acid, CARBONATE ION, GLYCEROL, ... | | 著者 | Ruggeri, C, Drinkwater, N, McGowan, S. | | 登録日 | 2015-07-01 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening.
Plos One, 10, 2015
|
|
4U75
 | | HsMetAP (F309M) in complex with Methionine | | 分子名称: | COBALT (II) ION, GLYCEROL, METHIONINE, ... | | 著者 | Arya, T, Addlagatta, A. | | 登録日 | 2014-07-30 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases
J.Med.Chem., 58, 2015
|
|
4U6E
 | | HsMetAP in complex with (amino(phenyl)methyl)phosphonic acid | | 分子名称: | COBALT (II) ION, Methionine aminopeptidase 1, [(R)-amino(phenyl)methyl]phosphonic acid | | 著者 | Arya, T, Addlagatta, A. | | 登録日 | 2014-07-28 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases
J.Med.Chem., 58, 2015
|
|
4U6Z
 | |
4U6J
 | | HsMetAP in complex with methionine | | 分子名称: | COBALT (II) ION, GLYCEROL, METHIONINE, ... | | 著者 | Arya, T, Addlagatta, A. | | 登録日 | 2014-07-29 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases
J.Med.Chem., 58, 2015
|
|
4U1B
 | |
4U69
 | |
4U70
 | |
4U76
 | | HsMetAP (F309M) holo form | | 分子名称: | COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ... | | 著者 | Arya, T, Addlagatta, A. | | 登録日 | 2014-07-30 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases
J.Med.Chem., 58, 2015
|
|
4U6C
 | |
4U73
 | |
8SLO
 | | Plasmodium falciparum M1 aminopeptidase bound to selective inhibitor MIPS2673 | | 分子名称: | 2-hydroxy-N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-2-methylpropanamide, GLYCEROL, M1 family aminopeptidase, ... | | 著者 | McGowan, S.M, Drinkwater, N. | | 登録日 | 2023-04-24 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as a cross-species strategy to treat malaria
Elife, 2024
|
|
3H7O
 | |
3H7T
 | |
4U6W
 | |
4U71
 | |
3LPC
 | | Crystal structure of a subtilisin-like protease | | 分子名称: | ACETATE ION, AprB2, CALCIUM ION, ... | | 著者 | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | | 登録日 | 2010-02-05 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Plos Pathog., 6, 2010
|
|
3LPA
 | | Crystal structure of a subtilisin-like protease | | 分子名称: | Acidic extracellular subtilisin-like protease AprV2, CALCIUM ION | | 著者 | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | | 登録日 | 2010-02-05 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Plos Pathog., 6, 2010
|
|
3LPD
 | | Crystal structure of a subtilisin-like protease | | 分子名称: | Acidic extracellular subtilisin-like protease AprV2, CALCIUM ION | | 著者 | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | | 登録日 | 2010-02-05 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Plos Pathog., 6, 2010
|
|
2NW0
 | |
