4U73

HsMetAP(F309M) IN COMPLEX WITH (amino(phenyl)methyl)phosphonic acid

Summary for 4U73

Related4u1b 4u69 4u6c 4u6e 4u6j 4u6w 4u6z 4u70 4u71 4u75 4u76
DescriptorMethionine aminopeptidase 1, COBALT (II) ION, POTASSIUM ION, ... (5 entities in total)
Functional Keywordshydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight34782.33
Authors
Arya, T.,Addlagatta, A. (deposition date: 2014-07-30, release date: 2015-03-25, Last modification date: 2019-11-20)
Primary citation
Arya, T.,Reddi, R.,Kishor, C.,Ganji, R.J.,Bhukya, S.,Gumpena, R.,McGowan, S.,Drag, M.,Addlagatta, A.
Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases
J.Med.Chem., 58:2350-2357, 2015
PubMed: 25699713 (PDB entries with the same primary citation)
DOI: 10.1021/jm501790e
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2063 0.3% 1.5% 0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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