4FNT
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![BU of 4fnt by Molmil](/molmil-images/mine/4fnt) | Crystal structure of GH36 alpha-galactosidase AgaA A355E D548N from Geobacillus stearothermophilus in complex with raffinose | Descriptor: | Alpha-galactosidase AgaA, alpha-D-galactopyranose-(1-6)-alpha-D-glucopyranose-(1-2)-beta-D-fructofuranose | Authors: | Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. | Deposit date: | 2012-06-20 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012
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4FNP
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![BU of 4fnp by Molmil](/molmil-images/mine/4fnp) | Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus | Descriptor: | Alpha-galactosidase AgaA, SULFATE ION | Authors: | Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. | Deposit date: | 2012-06-20 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012
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4FNQ
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![BU of 4fnq by Molmil](/molmil-images/mine/4fnq) | Crystal structure of GH36 alpha-galactosidase AgaB from Geobacillus stearothermophilus | Descriptor: | 1,2-ETHANEDIOL, Alpha-galactosidase AgaB | Authors: | Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. | Deposit date: | 2012-06-20 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012
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4FNU
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![BU of 4fnu by Molmil](/molmil-images/mine/4fnu) | Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose | Descriptor: | Alpha-galactosidase AgaA, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose-(1-6)-alpha-D-galactopyranose-(1-6)-alpha-D-galactopyranose | Authors: | Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. | Deposit date: | 2012-06-20 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012
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4FNR
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![BU of 4fnr by Molmil](/molmil-images/mine/4fnr) | Crystal structure of GH36 alpha-galactosidase AgaA from Geobacillus stearothermophilus | Descriptor: | Alpha-galactosidase AgaA | Authors: | Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. | Deposit date: | 2012-06-20 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012
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4FNS
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![BU of 4fns by Molmil](/molmil-images/mine/4fns) | Crystal structure of GH36 alpha-galactosidase AgaA A355E from Geobacillus stearothermophilus in complex with 1-deoxygalactonojirimycin | Descriptor: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, Alpha-galactosidase AgaA, ... | Authors: | Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. | Deposit date: | 2012-06-20 | Release date: | 2012-10-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies J.Biol.Chem., 287, 2012
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4U15
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![BU of 4u15 by Molmil](/molmil-images/mine/4u15) | M3-mT4L receptor bound to tiotropium | Descriptor: | (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, D(-)-TARTARIC ACID, ... | Authors: | Thorsen, T.S, Matt, R, Weis, W.I, Kobilka, B. | Deposit date: | 2014-07-15 | Release date: | 2014-11-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis. Structure, 22, 2014
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4U16
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![BU of 4u16 by Molmil](/molmil-images/mine/4u16) | M3-mT4L receptor bound to NMS | Descriptor: | D(-)-TARTARIC ACID, Muscarinic acetylcholine receptor M3,Lysozyme,Muscarinic acetylcholine receptor M3, N-methyl scopolamine | Authors: | Thorsen, T.S, Matt, R, Weis, W.I, Kobilka, B. | Deposit date: | 2014-07-15 | Release date: | 2014-11-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis. Structure, 22, 2014
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5UCJ
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![BU of 5ucj by Molmil](/molmil-images/mine/5ucj) | Hsp90b N-terminal domain with inhibitors | Descriptor: | (5-fluoroisoindolin-2-yl)(4-hydroxy-5-isopropylbenzo[d]isoxazol-7-yl)methanone, DIMETHYL SULFOXIDE, Heat shock protein HSP 90-beta | Authors: | Peng, S, Balch, M, Matts, R, Deng, J. | Deposit date: | 2016-12-22 | Release date: | 2018-01-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.693 Å) | Cite: | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor. Nat Commun, 9, 2018
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5UCI
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![BU of 5uci by Molmil](/molmil-images/mine/5uci) | Hsp90b N-terminal domain with inhibitors | Descriptor: | (2,4-Dihydroxy-3-(hydroxymethyl)-5-isopropylphenyl)(isoindolin-2-yl)methanone, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Peng, S, Balch, M, Matts, R, Deng, J. | Deposit date: | 2016-12-22 | Release date: | 2018-01-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor. Nat Commun, 9, 2018
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5UCH
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![BU of 5uch by Molmil](/molmil-images/mine/5uch) | Hsp90b N-terminal domain with inhibitors | Descriptor: | 2-(5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylphenyl)acetonitrile, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Peng, S, Balch, M, Matts, R, Deng, J. | Deposit date: | 2016-12-22 | Release date: | 2018-01-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.654 Å) | Cite: | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor. Nat Commun, 9, 2018
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5UC4
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![BU of 5uc4 by Molmil](/molmil-images/mine/5uc4) | Hsp90b N-terminal domain with inhibitors | Descriptor: | 5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylbenzaldehyde, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Deng, J, Peng, S, Balch, M, Matts, R. | Deposit date: | 2016-12-21 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor. Nat Commun, 9, 2018
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7UR3
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![BU of 7ur3 by Molmil](/molmil-images/mine/7ur3) | Hsp90 alpha inhibitor | Descriptor: | (5-fluoro-1,3-dihydro-2H-isoindol-2-yl){4-hydroxy-3-[(2S)-2-hydroxy-5-phenylpentan-2-yl]phenyl}methanone, Heat shock protein HSP 90-alpha | Authors: | Deng, J, Peng, S, Balch, M, Matts, R. | Deposit date: | 2022-04-21 | Release date: | 2022-12-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-Activity Relationship Study of Tertiary Alcohol Hsp90 alpha-Selective Inhibitors with Novel Binding Mode. Acs Med.Chem.Lett., 13, 2022
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1ZJA
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![BU of 1zja by Molmil](/molmil-images/mine/1zja) | Crystal structure of the trehalulose synthase MutB from Pseudomonas mesoacidophila MX-45 (triclinic form) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Trehalulose synthase | Authors: | Ravaud, S, Robert, X, Haser, R, Aghajari, N. | Deposit date: | 2005-04-28 | Release date: | 2006-10-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization. J.Biol.Chem., 282, 2007
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4GI9
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![BU of 4gi9 by Molmil](/molmil-images/mine/4gi9) | Crystal structure of the MUTB F164L mutant from crystals soaked with Trehalulose | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... | Authors: | Lipski, A, Haser, R, Aghajari, N. | Deposit date: | 2012-08-08 | Release date: | 2013-02-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity Acta Crystallogr.,Sect.D, 69, 2013
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4GI8
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![BU of 4gi8 by Molmil](/molmil-images/mine/4gi8) | Crystal structure of the MUTB F164L mutant from crystals soaked with the substrate sucrose | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... | Authors: | Lipski, A, Haser, R, Aghajari, N. | Deposit date: | 2012-08-08 | Release date: | 2013-02-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity Acta Crystallogr.,Sect.D, 69, 2013
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4GIN
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![BU of 4gin by Molmil](/molmil-images/mine/4gin) | Crystal structure of the MUTB R284C mutant from crystals soaked with the inhibitor deoxynojirimycin | Descriptor: | CALCIUM ION, GLYCEROL, Sucrose isomerase | Authors: | Lipski, A, Ravaud, S, Robert, X, Haser, R, Aghajari, N. | Deposit date: | 2012-08-08 | Release date: | 2013-02-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity Acta Crystallogr.,Sect.D, 69, 2013
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4GI6
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![BU of 4gi6 by Molmil](/molmil-images/mine/4gi6) | Crystal structure of the MUTB F164L mutant in complex with glucose | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... | Authors: | Lipski, A, Haser, R, Aghajari, N. | Deposit date: | 2012-08-08 | Release date: | 2013-02-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity Acta Crystallogr.,Sect.D, 69, 2013
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4GO9
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![BU of 4go9 by Molmil](/molmil-images/mine/4go9) | CRYSTAL STRUCTURE of the TREHALULOSE SYNTHASE MUTANT, MUTB D415N, in COMPLEX with TRIS | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Sucrose isomerase | Authors: | Lipski, A, Ravaud, S, Robert, X, Haser, R, Aghajari, N. | Deposit date: | 2012-08-19 | Release date: | 2013-08-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | CRYSTAL STRUCTURE of the TREHALULOSE SYNTHASE MUTB, MUTANT D415N, in COMPLEX with TRIS To be Published, 2013
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1ZJB
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![BU of 1zjb by Molmil](/molmil-images/mine/1zjb) | Crystal structure of the trehalulose synthase MutB from Pseudomonas mesoacidophila MX-45 (monoclinic form) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Trehalulose synthase | Authors: | Ravaud, S, Robert, X, Haser, R, Aghajari, N. | Deposit date: | 2005-04-28 | Release date: | 2006-10-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Expression, purification, crystallization and preliminary X-ray crystallographic studies of the trehalulose synthase MutB from Pseudomonas mesoacidophila MX-45. Acta Crystallogr.,Sect.F, 61, 2005
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3GBE
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![BU of 3gbe by Molmil](/molmil-images/mine/3gbe) | Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin | Descriptor: | 1,2-ETHANEDIOL, 1-DEOXYNOJIRIMYCIN, CITRATE ANION, ... | Authors: | Ravaud, S, Robert, X, Haser, R, Aghajari, N. | Deposit date: | 2009-02-19 | Release date: | 2009-05-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural determinants of product specificity of sucrose isomerases Febs Lett., 583, 2009
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3GBD
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![BU of 3gbd by Molmil](/molmil-images/mine/3gbd) | Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, Sucrose isomerase SmuA from Protaminobacter rubrum | Authors: | Ravaud, S, Robert, X, Haser, R, Aghajari, N. | Deposit date: | 2009-02-19 | Release date: | 2009-05-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural determinants of product specificity of sucrose isomerases Febs Lett., 583, 2009
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4GIA
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![BU of 4gia by Molmil](/molmil-images/mine/4gia) | Crystal structure of the MUTB F164L mutant from crystals soaked with isomaltulose | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... | Authors: | Lipski, A, Haser, R, Aghajari, N. | Deposit date: | 2012-08-08 | Release date: | 2013-02-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity Acta Crystallogr.,Sect.D, 69, 2013
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4H8V
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![BU of 4h8v by Molmil](/molmil-images/mine/4h8v) | |
4GO8
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![BU of 4go8 by Molmil](/molmil-images/mine/4go8) | Crystal Structure of the TREHALULOSE SYNTHASE MUTB, MUTANT A258V, in complex with TRIS | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Sucrose isomerase | Authors: | Lipski, A, Haser, R, Aghajari, N. | Deposit date: | 2012-08-19 | Release date: | 2013-08-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of MUTB A258V mutant in complex with TRIS To be Published, 2013
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