1A95
| XPRTASE FROM E. COLI COMPLEXED WITH MG:CPRPP AND GUANINE | Descriptor: | 1-ALPHA-PYROPHOSPHORYL-2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-CYCLOPENTANE-METHANOL-5-PHOSPHATE, BORIC ACID, GUANINE, ... | Authors: | Vos, S, Parry, R.J, Burns, M.R, De Jersey, J, Martin, J.L. | Deposit date: | 1998-04-16 | Release date: | 1998-11-11 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of free and complexed forms of Escherichia coli xanthine-guanine phosphoribosyltransferase. J.Mol.Biol., 282, 1998
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1A0M
| 1.1 ANGSTROM CRYSTAL STRUCTURE OF A-CONOTOXIN [TYR15]-EPI | Descriptor: | ALPHA-CONOTOXIN [TYR15]-EPI | Authors: | Hu, S.-H, Loughnan, M, Miller, R, Weeks, C.M, Blessing, R.H, Alewood, P.F, Lewis, R.J, Martin, J.L. | Deposit date: | 1997-12-03 | Release date: | 1999-01-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | The 1.1 A resolution crystal structure of [Tyr15]EpI, a novel alpha-conotoxin from Conus episcopatus, solved by direct methods. Biochemistry, 37, 1998
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1A97
| XPRTASE FROM E. COLI COMPLEXED WITH GMP | Descriptor: | BORIC ACID, GUANOSINE-5'-MONOPHOSPHATE, XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE | Authors: | Vos, S, Parry, R.J, Burns, M.R, De Jersey, J, Martin, J.L. | Deposit date: | 1998-04-16 | Release date: | 1998-11-11 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of free and complexed forms of Escherichia coli xanthine-guanine phosphoribosyltransferase. J.Mol.Biol., 282, 1998
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3BXR
| Crystal Structures Of Highly Constrained Substrate And Hydrolysis Products Bound To HIV-1 Protease. Implications For Catalytic Mechanism | Descriptor: | (9S,12S)-9-(1-methylethyl)-N-[(8S,11S)-8-[(1S)-1-methylpropyl]-7,10-dioxo-2-oxa-6,9-diazabicyclo[11.2.2]heptadeca-1(15),13,16-trien-11-yl]-7,10-dioxo-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-1(16),14,17-triene-12-carboxamide, Protease, SULFATE ION | Authors: | Tyndall, J.D, Pattenden, L.K, Reid, R.C, Hu, S.H, Alewood, D, Alewood, P.F, Walsh, T, Fairlie, D.P, Martin, J.L. | Deposit date: | 2008-01-14 | Release date: | 2008-03-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structures of Highly Constrained Substrate and Hydrolysis Products Bound to HIV-1 Protease. Implications for the Catalytic Mechanism Biochemistry, 47, 2008
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1AKG
| ALPHA-CONOTOXIN PNIB FROM CONUS PENNACEUS | Descriptor: | ALPHA-CONOTOXIN PNIB | Authors: | Hu, S.-H, Martin, J.L. | Deposit date: | 1997-05-18 | Release date: | 1998-05-20 | Last modified: | 2015-06-10 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Crystal structure at 1.1 A resolution of alpha-conotoxin PnIB: comparison with alpha-conotoxins PnIA and GI. Biochemistry, 36, 1997
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1A96
| XPRTASE FROM E. COLI WITH BOUND CPRPP AND XANTHINE | Descriptor: | 1-ALPHA-PYROPHOSPHORYL-2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-CYCLOPENTANE-METHANOL-5-PHOSPHATE, BORIC ACID, MAGNESIUM ION, ... | Authors: | Vos, S, Parry, R.J, Burns, M.R, De Jersey, J, Martin, J.L. | Deposit date: | 1998-04-16 | Release date: | 1998-11-11 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of free and complexed forms of Escherichia coli xanthine-guanine phosphoribosyltransferase. J.Mol.Biol., 282, 1998
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1BED
| STRUCTURE OF DISULFIDE OXIDOREDUCTASE | Descriptor: | DSBA OXIDOREDUCTASE | Authors: | Hu, S.-H, Martin, J.L. | Deposit date: | 1996-09-16 | Release date: | 1997-10-08 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of TcpG, the DsbA protein folding catalyst from Vibrio cholerae. J.Mol.Biol., 268, 1997
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5TLQ
| Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex | Descriptor: | 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine, Thiol:disulfide interchange protein DsbA | Authors: | Mohanty, B, Rimmer, K.A, McMahon, R.M, Headey, S.J, Vazirani, M, Shouldice, S.R, Coincon, M, Tay, S, Morton, C.J, Simpson, J.S, Martin, J.L, Scanlon, M.S. | Deposit date: | 2016-10-11 | Release date: | 2017-04-12 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1. PLoS ONE, 12, 2017
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5U3E
| Crystal Structure of Native Lectin from Canavalia bonariensis Seeds (CaBo) complexed with alpha-methyl-D-mannoside | Descriptor: | CALCIUM ION, Canavalia bonariensis seed lectin, MANGANESE (II) ION, ... | Authors: | Silva, M.T.L, Osterne, V.J.S, Pinto-Junior, V.R, Santiago, M.Q, Araripe, D.A, Neco, A.H.B, Silva-Filho, J.C, Martins, J.L, Rocha, C.R.C, Leal, R.B, Nascimento, K.S, Cavada, B.S. | Deposit date: | 2016-12-02 | Release date: | 2017-08-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Canavalia bonariensis lectin: Molecular bases of glycoconjugates interaction and antiglioma potential. Int. J. Biol. Macromol., 106, 2018
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5VYO
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3PUK
| Re-refinement of the crystal structure of Munc18-3 and Syntaxin4 N-peptide complex | Descriptor: | Syntaxin-4 N-terminal peptide, Syntaxin-binding protein 3 | Authors: | Hu, S.-H, Christie, M.P, Saez, N.J, Latham, C.F, Jarrott, R, Lua, L.H.L, Collins, B.M, Martin, J.L. | Deposit date: | 2010-12-05 | Release date: | 2011-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.054 Å) | Cite: | Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation Proc.Natl.Acad.Sci.USA, 108, 2011
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1NUL
| XPRTASE FROM E. COLI | Descriptor: | MAGNESIUM ION, SULFATE ION, XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE | Authors: | Vos, S, De Jersey, J, Martin, J.L. | Deposit date: | 1996-10-15 | Release date: | 1997-05-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Escherichia coli xanthine phosphoribosyltransferase. Biochemistry, 36, 1997
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6C29
| Crystal structure of the N-terminal periplasmic domain of ScsB from Proteus mirabilis | Descriptor: | Putative metal resistance protein | Authors: | Furlong, E.J, Choudhury, H.G, Kurth, F, Martin, J.L. | Deposit date: | 2018-01-07 | Release date: | 2018-03-07 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.538 Å) | Cite: | Disulfide isomerase activity of the dynamic, trimericProteus mirabilisScsC protein is primed by the tandem immunoglobulin-fold domain of ScsB. J. Biol. Chem., 293, 2018
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1J1A
| PANCREATIC SECRETORY PHOSPHOLIPASE A2 (IIa) WITH ANTI-INFLAMMATORY ACTIVITY | Descriptor: | (S)-5-(4-BENZYLOXY-PHENYL)-4-(7-PHENYL-HEPTANOYLAMINO)-PENTANOIC ACID, CALCIUM ION, Phospholipase A2 | Authors: | Hansford, K.A, Reid, R.C, Clark, C.I, Tyndall, J.D.A, Whitehouse, M.W, Guthrie, T, McGeary, R.P, Schafer, K, Martin, J.L, Fairlie, D.P. | Deposit date: | 2002-12-03 | Release date: | 2003-03-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | D-Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A2 (IIa) with Antiinflammatory Activity Chembiochem, 4, 2003
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1UTE
| PIG PURPLE ACID PHOSPHATASE COMPLEXED WITH PHOSPHATE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ISOPROPYL ALCOHOL, MU-OXO-DIIRON, ... | Authors: | Guddat, L.W, Mcalpine, A, Hume, D, Hamilton, S, De Jersey, J, Martin, J.L. | Deposit date: | 1999-01-18 | Release date: | 1999-10-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of mammalian purple acid phosphatase. Structure Fold.Des., 7, 1999
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1WNH
| Crystal structure of mouse Latexin (tissue carboxypeptidase inhibitor) | Descriptor: | Latexin | Authors: | Aagaard, A, Listwan, P, Cowieson, N, Huber, T, Ravasi, T, Wells, C.A, Flanagan, J.U, Hume, D.A, Kobe, B, Martin, J.L. | Deposit date: | 2004-08-04 | Release date: | 2005-02-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | An Inflammatory Role for the Mammalian Carboxypeptidase Inhibitor Latexin: Relationship to Cystatins and the Tumor Suppressor TIG1 Structure, 13, 2005
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1LS6
| Human SULT1A1 complexed with PAP and p-Nitrophenol | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, P-NITROPHENOL, aryl sulfotransferase | Authors: | Gamage, N.U, Barnett, A.C, Tresillian, M, Latham, C.F, Liyou, N.E, McManus, M.E, Martin, J.L. | Deposit date: | 2002-05-17 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition. J.Biol.Chem., 278, 2003
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1YZ3
| Structure of human pnmt complexed with cofactor product adohcy and inhibitor SK&F 64139 | Descriptor: | 7,8-DICHLORO-1,2,3,4-TETRAHYDROISOQUINOLINE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Wu, Q, Gee, C.L, Lin, F, Martin, J.L, Grunewald, G.L, McLeish, M.J. | Deposit date: | 2005-02-27 | Release date: | 2006-02-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase J.Med.Chem., 48, 2005
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1N7I
| The structure of Phenylethanolamine N-methyltransferase in complex with S-adenosylhomocysteine and the inhibitor LY134046 | Descriptor: | 8,9-DICHLORO-2,3,4,5-TETRAHYDRO-1H-BENZO[C]AZEPINE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | McMillan, F.M, Archbold, J, McLeish, M.J, Caine, J.M, Criscione, K.R, Grunewald, G.L, Martin, J.L. | Deposit date: | 2002-11-15 | Release date: | 2003-12-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular recognition of sub-micromolar inhibitors by the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase. J.Med.Chem., 47, 2004
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1N7J
| The structure of Phenylethanolamine N-methyltransferase in complex with S-adenosylhomocysteine and an iodinated inhibitor | Descriptor: | 7-IODO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | McMillan, F.M, Archbold, J, McLeish, M.J, Caine, J.M, Criscione, K.R, Grunewald, G.L, Martin, J.L. | Deposit date: | 2002-11-15 | Release date: | 2003-12-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular recognition of sub-micromolar inhibitors by the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase. J.Med.Chem., 47, 2004
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1MTR
| HIV-1 PROTEASE COMPLEXED WITH A CYCLIC PHE-ILE-VAL PEPTIDOMIMETIC INHIBITOR | Descriptor: | HIV-1 PROTEASE, SULFATE ION, [1-BENZYL-3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YLAMINO)-2-HYDROXY-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTER | Authors: | Wickramasinghe, W, Begun, J, Martin, J.L. | Deposit date: | 1996-02-15 | Release date: | 1996-08-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode. J.Am.Chem.Soc., 118, 1996
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6EEZ
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2Y92
| Crystal structure of MAL adaptor protein | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN, | Authors: | Valkov, E, Stamp, A, Martin, J.L, Kobe, B. | Deposit date: | 2011-02-11 | Release date: | 2011-09-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Crystal Structure of Toll-Like Receptor Adaptor Mal/Tirap Reveals the Molecular Basis for Signal Transduction and Disease Protection. Proc.Natl.Acad.Sci.USA, 108, 2011
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3AX4
| Three-dimensional structure of lectin from Dioclea violacea and comparative vasorelaxant effects with Dioclea rostrata | Descriptor: | 5-bromo-4-chloro-1H-indol-3-yl alpha-D-mannopyranoside, CALCIUM ION, MANGANESE (II) ION, ... | Authors: | Bezerra, M.J.B, Bezerra, G.A, Martins, J.L, Nascimento, K.S, Nagano, C.S, Gruber, K, Assereuy, A.M, Delatorre, P, Rocha, B.A.M, Cavada, B.S. | Deposit date: | 2011-03-29 | Release date: | 2012-04-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.613 Å) | Cite: | Crystal structure of Dioclea violacea lectin and a comparative study of vasorelaxant properties with Dioclea rostrata lectin Int.J.Biochem.Cell Biol., 45, 2013
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4XVW
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