1LS6

Human SULT1A1 complexed with PAP and p-Nitrophenol

Summary for 1LS6

Entry DOI	10.2210/pdb1ls6/pdb
Descriptor	aryl sulfotransferase, ADENOSINE-3'-5'-DIPHOSPHATE, P-NITROPHENOL, ... (4 entities in total)
Functional Keywords	sult 1a1, pap, p-nitrophenol, positive cooperativity, two substrate binding sites, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P50225
Total number of polymer chains	1
Total formula weight	34925.73
Authors	Gamage, N.U.,Barnett, A.C.,Tresillian, M.,Latham, C.F.,Liyou, N.E.,McManus, M.E.,Martin, J.L. (deposition date: 2002-05-17, release date: 2003-08-05, Last modification date: 2024-02-14)
Primary citation	Gamage, N.U.,Duggleby, R.G.,Barnett, A.C.,Tresillian, M.,Latham, C.F.,Liyou, N.E.,McManus, M.E.,Martin, J.L. Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition. J.Biol.Chem., 278:7655-7662, 2003 Cited by PubMed: 12471039 DOI: 10.1074/jbc.M207246200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation