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1ZMR
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Crystal Structure of the E. coli Phosphoglycerate Kinase
分子名称: CALCIUM ION, Phosphoglycerate kinase
著者Marqusee, S.
登録日2005-05-10
公開日2006-05-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Comparison of proteolytic susceptibility in phosphoglycerate kinases from yeast and E. coli: modulation of conformational ensembles without altering structure or stability.
J.Mol.Biol., 368, 2007
8TQO
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Eukaryotic translation initiation factor 2B tetramer
分子名称: Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, Translation initiation factor eIF-2B subunit epsilon, ...
著者Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P.
登録日2023-08-08
公開日2023-12-06
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling.
Nat.Chem.Biol., 20, 2024
8TQZ
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Eukaryotic translation initiation factor 2B with a mutation (L516A) in the delta subunit
分子名称: Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ...
著者Wang, L, Lawrence, R, Sangwan, S, Anand, A, Shoemaker, S, Deal, A, Marqusee, S, Watler, P.
登録日2023-08-08
公開日2023-12-06
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling.
Nat.Chem.Biol., 20, 2024
3H08
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BU of 3h08 by Molmil
Crystal structure of the Ribonuclease H1 from Chlorobium tepidum
分子名称: MAGNESIUM ION, Rnh (Ribonuclease H)
著者Ratcliff, K, Corn, J, Marqusee, S.
登録日2009-04-08
公開日2009-05-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure, stability, and folding of ribonuclease H1 from the moderately thermophilic chlorobium tepidum: comparison with thermophilic and mesophilic homologues.
Biochemistry, 48, 2009
7UI5
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BU of 7ui5 by Molmil
Evolution avoids a pathological stabilizing interaction in the immune protein S100A9
分子名称: CALCIUM ION, Protein S100-A9
著者Reardon, P.N, Harman, J.L, Costello, S.M, Warren, G.D, Phillips, S.R, Connor, P.J, Marqusee, S, Harms, M.J.
登録日2022-03-28
公開日2022-10-26
実験手法SOLUTION NMR
主引用文献Evolution avoids a pathological stabilizing interaction in the immune protein S100A9.
Proc.Natl.Acad.Sci.USA, 119, 2022
4LY7
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Ancestral RNase H
分子名称: Ribonuclease H, SULFATE ION
著者Hart, K.M, Harms, M.J, Schmidt, B.H, Elya, C, Thornton, J.W, Marqusee, S.
登録日2013-07-30
公開日2014-11-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Thermodynamic system drift in protein evolution.
Plos Biol., 12, 2014
1JL2
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BU of 1jl2 by Molmil
Crystal structure of TCEO RNase H-a chimera combining the folding core from T. thermophilus RNase H and the remaining region of E. coli RNase H
分子名称: Chimera of Ribonuclease HI, Ribonuclease H
著者Robic, S, Berger, J.M, Marqusee, S.
登録日2001-07-13
公開日2002-01-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Contributions of folding cores to the thermostabilities of two ribonucleases H.
Protein Sci., 11, 2002
1JXB
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I53A, a point mutant of the cysteine-free variant of E. coli Rnase HI
分子名称: Ribonuclease HI
著者Spudich, G, Lorenz, S, Marqusee, S.
登録日2001-09-06
公開日2002-03-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Propagation of a single destabilizing mutation throughout the Escherichia coli ribonuclease HI native state.
Protein Sci., 11, 2002
2II0
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Crystal Structure of catalytic domain of Son of sevenless (Rem-Cdc25) in the absence of Ras
分子名称: Son of sevenless homolog 1
著者Freedman, T.S, Sondermann, H, Friedland, G.D, Kortemme, T, Bar-Sagi, D, Marqusee, S, Kuriyan, J.
登録日2006-09-27
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献A Ras-induced conformational switch in the Ras activator Son of sevenless.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1JL1
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D10A E. coli ribonuclease HI
分子名称: RIBONUCLEASE HI
著者Goedken, E.R, Marqusee, S.
登録日2001-07-13
公開日2002-02-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Native-state energetics of a thermostabilized variant of ribonuclease HI.
J.Mol.Biol., 314, 2001
2O79
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T4 lysozyme with C-terminal extension
分子名称: CHLORIDE ION, GLYCEROL, Lysozyme, ...
著者Llinas, M, Crowder, S.M, Echols, N, Alber, T, Marqusee, S.
登録日2006-12-10
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment.
Protein Sci., 16, 2007
2O4W
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T4 lysozyme circular permutant
分子名称: CHLORIDE ION, Lysozyme
著者Llinas, M, Crowder, S.M, Echols, N, Alber, T, Marqusee, S.
登録日2006-12-05
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment.
Protein Sci., 16, 2007
1F21
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DIVALENT METAL COFACTOR BINDING IN THE KINETIC FOLDING TRAJECTORY OF E. COLI RIBONUCLEASE HI
分子名称: RIBONUCLEASE HI
著者Goedken, E.R, Keck, J.L, Berger, J.M, Marqusee, S.
登録日2000-05-22
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Divalent metal cofactor binding in the kinetic folding trajectory of Escherichia coli ribonuclease HI.
Protein Sci., 9, 2000
1G15
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CO-CRYSTAL OF E. COLI RNASE HI WITH TWO MN2+ IONS BOUND IN THE THE ACTIVE SITE
分子名称: MANGANESE (II) ION, RIBONUCLEASE HI
著者Goedken, E.R, Marqusee, S.
登録日2000-10-10
公開日2001-03-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Co-crystal of Escherichia coli RNase HI with Mn2+ ions reveals two divalent metals bound in the active site.
J.Biol.Chem., 276, 2001
1DOF
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BU of 1dof by Molmil
THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY
分子名称: ADENYLOSUCCINATE LYASE
著者Toth, E.A, Yeates, T.O, Goedken, E, Dixon, J.E, Marqusee, S.
登録日1999-12-20
公開日2001-01-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds.
J.Mol.Biol., 301, 2000
6XHZ
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Alpha-lytic protease homolog N4
分子名称: N4: hypothetical protein, SULFATE ION
著者Nixon, C.F, Marqusee, S.M, Gee, C.L.
登録日2020-06-19
公開日2021-01-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Exploring the Evolutionary History of Kinetic Stability in the alpha-Lytic Protease Family.
Biochemistry, 60, 2021
6UEW
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BU of 6uew by Molmil
Rubisco / CsoS2 N-peptide complex responsible for alpha-carboxysome cargo loading
分子名称: Ribulose bisphosphate carboxylase large chain, CsoS2 N-peptide fusion, Ribulose bisphosphate carboxylase small chain
著者Oltrogge, L.M, Savage, D.F.
登録日2019-09-23
公開日2019-10-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Multivalent interactions between CsoS2 and Rubisco mediate alpha-carboxysome formation.
Nat.Struct.Mol.Biol., 27, 2020
7SA7
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BU of 7sa7 by Molmil
Crystal structure of the apo SH2 domains of Syk
分子名称: Tyrosine-protein kinase SYK
著者Hobbs, H.T, Badroos, J, Gee, C.L, Kuriyan, J.
登録日2021-09-22
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases.
Protein Sci., 30, 2021
2O7A
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T4 lysozyme C-terminal fragment
分子名称: ACETATE ION, CHLORIDE ION, Lysozyme
著者Echols, N, Kwon, E, Marqusee, S.M, Alber, T.
登録日2006-12-10
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (0.84 Å)
主引用文献Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment.
Protein Sci., 16, 2007
8FU6
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GCGR-Gs complex in the presence of RAMP2
分子名称: Glucagon derivative ZP3780, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Krishna Kumar, K, O'Brien, E.S, Wang, H, Montabana, E, Kobilka, B.K.
登録日2023-01-16
公開日2023-04-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Negative allosteric modulation of the glucagon receptor by RAMP2.
Cell, 186, 2023
4Z0U
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RNase HI/SSB-Ct complex
分子名称: Ribonuclease H, SSB-Ct Peptide
著者Petzold, C, Keck, J.L.
登録日2015-03-26
公開日2015-04-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Interaction with Single-stranded DNA-binding Protein Stimulates Escherichia coli Ribonuclease HI Enzymatic Activity.
J.Biol.Chem., 290, 2015
2IJE
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Crystal Structure of the Cdc25 domain of RasGRF1
分子名称: GLYCEROL, Guanine nucleotide-releasing protein
著者Freedman, T.S, Kuriyan, J.
登録日2006-09-29
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Ras-induced conformational switch in the Ras activator Son of sevenless.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1F1O
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STRUCTURAL STUDIES OF ADENYLOSUCCINATE LYASES
分子名称: ADENYLOSUCCINATE LYASE
著者Toth, E.A, Yeates, T.
登録日2000-05-19
公開日2001-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds.
J.Mol.Biol., 301, 2000
8T8M
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Quis-bound intermediate mGlu5
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Metabotropic glutamate receptor 5, Nb43
著者Krishna Kumar, K, Wang, H, Kobilka, B.K.
登録日2023-06-22
公開日2023-10-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Step-wise activation of a Family C GPCR.
Biorxiv, 2023
8T6J
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CDPPB-bound inactive mGlu5
分子名称: 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide, Metabotropic glutamate receptor 5
著者Krishna Kumar, K, Wang, H, Kobilka, B.K.
登録日2023-06-16
公開日2023-10-11
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Step-wise activation of a Family C GPCR.
Biorxiv, 2023

 

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