2AQ2
 
 | | Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant | | Descriptor: | Enterotoxin type C-3, SODIUM ION, SULFATE ION, ... | | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | | Deposit date: | 2005-08-17 | | Release date: | 2006-03-21 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
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2APW
 | | Crystal Structure of the G17E/A52V/S54N/K66E/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain | | Descriptor: | MALONIC ACID, T cell receptor beta chain V | | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | | Deposit date: | 2005-08-16 | | Release date: | 2006-03-21 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
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2APV
 | | Crystal Structure of the G17E/A52V/S54N/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain | | Descriptor: | MALONIC ACID, T cell receptor beta chain V | | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | | Deposit date: | 2005-08-16 | | Release date: | 2006-03-21 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
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2AQ1
 | | Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant | | Descriptor: | Enterotoxin type C-3, T-cell receptor beta chain V | | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | | Deposit date: | 2005-08-17 | | Release date: | 2006-03-21 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
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2APF
 | | Crystal Structure of the A52V/S54N/K66E variant of the murine T cell receptor V beta 8.2 domain | | Descriptor: | MALONIC ACID, T cell receptor beta chain V | | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | | Deposit date: | 2005-08-16 | | Release date: | 2006-03-21 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
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2APT
 | | Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain | | Descriptor: | MALONIC ACID, T-cell receptor beta chain V | | Authors: | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | | Deposit date: | 2005-08-16 | | Release date: | 2006-03-21 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
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1FM5
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1G7H
 | | CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3(VLW92A) | | Descriptor: | ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C | | Authors: | Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A. | | Deposit date: | 2000-11-10 | | Release date: | 2000-11-22 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
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1G7J
 | | CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92H) | | Descriptor: | ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C | | Authors: | Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A. | | Deposit date: | 2000-11-10 | | Release date: | 2000-11-22 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
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1G7M
 | | CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V) | | Descriptor: | ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C | | Authors: | Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A. | | Deposit date: | 2000-11-10 | | Release date: | 2000-11-22 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
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1G7L
 | | CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92S) | | Descriptor: | ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C | | Authors: | Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A. | | Deposit date: | 2000-11-10 | | Release date: | 2000-11-22 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
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1G7I
 | | CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92F) | | Descriptor: | ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C, PHOSPHATE ION | | Authors: | Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A. | | Deposit date: | 2000-11-10 | | Release date: | 2000-11-22 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
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1JWU
 | | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the superantigen SEC3 Variant 3B2 | | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | | Deposit date: | 2001-09-05 | | Release date: | 2003-07-08 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation
Structure, 11, 2003
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1JWS
 | | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the Superantigen SEC3 Variant 3B1 | | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | | Deposit date: | 2001-09-05 | | Release date: | 2003-07-08 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation
Structure, 11, 2003
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1JNE
 | | Crystal structure of imaginal disc growth factor-2 | | Descriptor: | Imaginal disc growth factor-2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Varela, P.F, Llera, A.S, Mariuzza, R.A, Tormo, J. | | Deposit date: | 2001-07-23 | | Release date: | 2002-05-01 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster.
J.Biol.Chem., 277, 2002
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1JWM
 | | Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1(HA peptide 306-318) with the Superantigen SEC3 | | Descriptor: | Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ... | | Authors: | Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A. | | Deposit date: | 2001-09-04 | | Release date: | 2003-07-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity
maturation
Structure, 11, 2003
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1JND
 | | Crystal structure of imaginal disc growth factor-2 | | Descriptor: | Imaginal disc growth factor-2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Varela, P.F, Llera, A.S, Mariuzza, R.A, Tormo, J. | | Deposit date: | 2001-07-23 | | Release date: | 2002-05-01 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster.
J.Biol.Chem., 277, 2002
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1KLU
 | | Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | | Descriptor: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | | Authors: | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | | Deposit date: | 2001-12-12 | | Release date: | 2002-08-02 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
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4PO4
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2NTT
 | | Crystal Structure of SEK | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Staphylococcal enterotoxin K | | Authors: | Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J. | | Deposit date: | 2006-11-08 | | Release date: | 2007-06-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.561 Å) | | Cite: | A novel loop domain in superantigens extends their T cell receptor recognition site
J.Mol.Biol., 371, 2007
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2NTS
 | | Crystal Structure of SEK-hVb5.1 | | Descriptor: | Staphylococcal enterotoxin K, TRBC1 protein | | Authors: | Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J. | | Deposit date: | 2006-11-08 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A novel loop domain in superantigens extends their T cell receptor recognition site
J.Mol.Biol., 371, 2007
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8FSJ
 | | Cryo-EM structure of engineered hepatitis C virus E1E2 ectodomain in complex with antibodies AR4A, HEPC74, and IGH520 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AR4A heavy chain, ... | | Authors: | Metcalf, M.C, Ofek, G. | | Deposit date: | 2023-01-10 | | Release date: | 2023-07-19 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies.
Nat Commun, 14, 2023
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8DNT
 | | SARS-CoV-2 specific T cell receptor | | Descriptor: | Beta-2-microglobulin, MHC class I antigen alpha chain, Nucleoprotein, ... | | Authors: | Gallagher, D.T, Wu, D, Gowthaman, R, Pierce, B.G, Mariuzza, R.A, Weng, N.P. | | Deposit date: | 2022-07-11 | | Release date: | 2023-07-19 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | SARS-CoV-2 infection establishes a stable and age-independent CD8 + T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Nat Commun, 14, 2023
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4IOP
 | | Crystal structure of NKp65 bound to its ligand KACL | | Descriptor: | C-type lectin domain family 2 member A, Killer cell lectin-like receptor subfamily F member 2, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Li, Y. | | Deposit date: | 2013-01-08 | | Release date: | 2013-07-17 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of NKp65 bound to its keratinocyte ligand reveals basis for genetically linked recognition in natural killer gene complex.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4IS6
 | | Crystal structure of HLA-DR4 bound to GP100 peptide | | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ... | | Authors: | Li, Y. | | Deposit date: | 2013-01-16 | | Release date: | 2013-10-23 | | Last modified: | 2013-11-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure-Based Design of Altered MHC Class II-Restricted Peptide Ligands with Heterogeneous Immunogenicity.
J.Immunol., 191, 2013
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