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8A00
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BU of 8a00 by Molmil
Infectious mouse-adapted ME7 scrapie prion fibril purified from terminally-infected mouse brains
Descriptor: Major prion protein
Authors:Manka, S.W, Wenborn, A, Betts, J, Joiner, S, Saibil, H.R, Collinge, J, Wadsworth, J.D.F.
Deposit date:2022-05-26
Release date:2023-01-18
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:A structural basis for prion strain diversity.
Nat.Chem.Biol., 19, 2023
6EW0
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BU of 6ew0 by Molmil
Cryo-EM structure of GDP-microtubule co-polymerised with doublecortin and supplemented with Taxol
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Manka, S.W.
Deposit date:2017-11-03
Release date:2018-07-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nat. Struct. Mol. Biol., 25, 2018
6EVZ
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BU of 6evz by Molmil
Cryo-EM structure of GDP-microtubule co-polymerised with doublecortin
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Manka, S.W.
Deposit date:2017-11-03
Release date:2018-07-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nat. Struct. Mol. Biol., 25, 2018
6EVX
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BU of 6evx by Molmil
Cryo-EM structure of GDP.Pi-microtubule rapidly co-polymerised with doublecortin
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Manka, S.W.
Deposit date:2017-11-03
Release date:2018-07-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nat. Struct. Mol. Biol., 25, 2018
6EVY
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BU of 6evy by Molmil
Cryo-EM structure of GTPgammaS-microtubule co-polymerised with doublecortin
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Manka, S.W.
Deposit date:2017-11-03
Release date:2018-07-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nat. Struct. Mol. Biol., 25, 2018
6EVW
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BU of 6evw by Molmil
Cryo-EM structure of GMPCPP-microtubule co-polymerised with doublecortin
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Manka, S.W.
Deposit date:2017-11-02
Release date:2018-07-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nat. Struct. Mol. Biol., 25, 2018
7QIG
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BU of 7qig by Molmil
Infectious mouse-adapted RML scrapie prion fibril purified from terminally-infected mouse brains
Descriptor: Major prion protein
Authors:Manka, S.W, Zhang, W, Wenborn, A, Betts, J, Joiner, S, Saibil, H.R, Collinge, J, Wadsworth, J.D.F.
Deposit date:2021-12-14
Release date:2022-07-27
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:2.7 angstrom cryo-EM structure of ex vivo RML prion fibrils.
Nat Commun, 13, 2022
6REV
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BU of 6rev by Molmil
Cryo-EM structure of the N-terminal DC repeat (NDC) of human doublecortin (DCX) bound to 13-protofilament GDP-microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Manka, S.W.
Deposit date:2019-04-12
Release date:2020-05-13
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Pseudo-repeats in doublecortin make distinct mechanistic contributions to microtubule regulation.
Embo Rep., 21, 2020
4AUO
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BU of 4auo by Molmil
Crystal structure of MMP-1(E200A) in complex with a triple-helical collagen peptide
Descriptor: CALCIUM ION, INTERSTITIAL COLLAGENASE, TRIPLE-HELICAL COLLAGEN PEPTIDE, ...
Authors:Manka, S.W, Carafoli, F, Visse, R, Bihan, D, Raynal, N, Farndale, R.W, Murphy, G, Enghild, J.J, Hohenester, E, Nagase, H.
Deposit date:2012-05-18
Release date:2012-07-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights Into Triple-Helical Collagen Cleavage by Matrix Metalloproteinase 1
Proc.Natl.Acad.Sci.USA, 109, 2012
6RF2
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BU of 6rf2 by Molmil
Cryo-EM structure of the C-terminal DC repeat (CDC) of human doublecortin (DCX) bound to 13-protofilament GDP.Pi-microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Manka, S.W.
Deposit date:2019-04-12
Release date:2020-05-13
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Pseudo-repeats in doublecortin make distinct mechanistic contributions to microtubule regulation.
Embo Rep., 21, 2020
6RFD
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BU of 6rfd by Molmil
Cryo-EM structure of the N-terminal DC repeat (NDC) of NDC-NDC chimera (human sequence) bound to 14-protofilament GDP-microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Manka, S.W.
Deposit date:2019-04-12
Release date:2020-05-13
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Pseudo-repeats in doublecortin make distinct mechanistic contributions to microtubule regulation.
Embo Rep., 21, 2020
6RF8
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BU of 6rf8 by Molmil
Cryo-EM structure of the N-terminal DC repeat (NDC) of NDC-NDC chimera (human sequence) bound to 13-protofilament GDP-microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Manka, S.W.
Deposit date:2019-04-12
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A microtubule RELION-based pipeline for cryo-EM image processing.
J.Struct.Biol., 209, 2020

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PDB entries from 2024-11-20

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