Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6P86
DownloadVisualize
BU of 6p86 by Molmil
E.coli LpxD in complex with compound 4.1
分子名称: 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, N-[(4-ethylphenyl)methyl]-2-[(6aR)-6-oxo-3-(pyrrolidine-1-carbonyl)-6,6a,7,8,9,10-hexahydro-5H-pyrido[1,2-a]quinoxalin-5-yl]acetamide, ...
著者Ma, X, Shia, S.
登録日2019-06-06
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
Acs Infect Dis., 6, 2020
6P88
DownloadVisualize
BU of 6p88 by Molmil
E.coli LpxD in complex with compound 6
分子名称: 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, N-{3-[(furan-2-carbonyl)amino]phenyl}-2,3-dihydro-1,4-benzodioxine-6-carboxamide, ...
著者Ma, X, Shia, S.
登録日2019-06-06
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
Acs Infect Dis., 6, 2020
6P85
DownloadVisualize
BU of 6p85 by Molmil
E.coli LpxD in complex with compound 3
分子名称: 1-(2-ethoxyphenyl)-4-[(4-methylphenyl)sulfonyl]-1H-1,2,3-triazol-5-amine, 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, ...
著者Ma, X, Shia, S.
登録日2019-06-06
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
Acs Infect Dis., 6, 2020
6P89
DownloadVisualize
BU of 6p89 by Molmil
E.coli LpxD in complex with compound 7
分子名称: 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(8-methyl[1]benzopyrano[4,3-c]pyrazol-1(4H)-yl)acetamide, ...
著者Ma, X, Shia, S.
登録日2019-06-06
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
Acs Infect Dis., 6, 2020
6P87
DownloadVisualize
BU of 6p87 by Molmil
E.coli LpxD in complex with compound 5
分子名称: 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, N-[(R)-(1H-indol-3-yl)(thiophen-2-yl)methyl]-2-(2-methoxyphenoxy)-N-methylacetamide, ...
著者Ma, X, Shia, S.
登録日2019-06-06
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
Acs Infect Dis., 6, 2020
6P8B
DownloadVisualize
BU of 6p8b by Molmil
E.coli LpxD in complex with peptide FITC-RJPXD33
分子名称: 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, FITC-RJPXD33, MAGNESIUM ION, ...
著者Ma, X, Shia, S.
登録日2019-06-06
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
Acs Infect Dis., 6, 2020
2BGH
DownloadVisualize
BU of 2bgh by Molmil
Crystal structure of Vinorine Synthase
分子名称: VINORINE SYNTHASE
著者Ma, X, Koepke, J, Panjikar, S, Fritzsch, G, Stoeckigt, J.
登録日2004-12-22
公開日2005-01-24
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Vinorine Synthase, the First Representative of the Bahd Superfamily.
J.Biol.Chem., 280, 2005
6P84
DownloadVisualize
BU of 6p84 by Molmil
E.coli LpxD in complex with compound 2o
分子名称: 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase
著者Ma, X, Shia, S.
登録日2019-06-06
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
Acs Infect Dis., 6, 2020
6P8A
DownloadVisualize
BU of 6p8a by Molmil
E.coli LpxD in complex with compound 8.1
分子名称: 2-[4,6-dimethyl-3-(1H-pyrrol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]-N-[3-(morpholin-4-yl)propyl]acetamide, 3-hydroxy-7,7-dimethyl-2-phenyl-4-(thiophen-2-yl)-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, ...
著者Ma, X, Shia, S.
登録日2019-06-06
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
Acs Infect Dis., 6, 2020
6P83
DownloadVisualize
BU of 6p83 by Molmil
E.coli LpxD in complex with compound 1o
分子名称: 4-(2-chlorophenyl)-3-hydroxy-7,7-dimethyl-2-phenyl-2,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, MAGNESIUM ION, UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase
著者Ma, X, Shia, S.
登録日2019-06-06
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
Acs Infect Dis., 6, 2020
2O0C
DownloadVisualize
BU of 2o0c by Molmil
Crystal structure of the H-NOX domain from Nostoc sp. PCC 7120 complexed to NO
分子名称: Alr2278 protein, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE
著者Ma, X, van den Akker, F.
登録日2006-11-27
公開日2007-01-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism.
Embo J., 26, 2007
2O09
DownloadVisualize
BU of 2o09 by Molmil
Crystal structure of the H-NOX domain from Nostoc sp. PCC 7120
分子名称: Alr2278 protein, PROTOPORPHYRIN IX CONTAINING FE
著者Ma, X, van den Akker, F.
登録日2006-11-27
公開日2007-01-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism.
Embo J., 26, 2007
2O0G
DownloadVisualize
BU of 2o0g by Molmil
Crystal structure of the H-NOX domain from Nostoc sp. PCC 7120 complexed to CO
分子名称: Alr2278 protein, CARBON MONOXIDE, PROTOPORPHYRIN IX CONTAINING FE
著者Ma, X, van den Akker, F.
登録日2006-11-27
公開日2007-01-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism.
Embo J., 26, 2007
3HLS
DownloadVisualize
BU of 3hls by Molmil
Crystal structure of the signaling helix coiled-coil doimain of the BETA-1 subunit of the soluble guanylyl cyclase
分子名称: Guanylate cyclase soluble subunit beta-1
著者Ma, X, van den Akker, F.
登録日2009-05-28
公開日2010-01-19
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the signaling helix coiled-coil domain of the beta-1 subunit of the soluble guanylyl cyclase.
Bmc Struct.Biol., 10, 2010
4EUU
DownloadVisualize
BU of 4euu by Molmil
Structure of BX-795 Complexed with Human TBK1 Kinase Domain Phosphorylated on Ser172
分子名称: GLYCEROL, IODIDE ION, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, ...
著者Ma, X, Helgason, E, Phung, Q.T, Quan, C.L, Iyer, R.S, Lee, M.W, Bowman, K.K, Starovasnik, M.A, Dueber, E.C.
登録日2012-04-25
公開日2012-05-23
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation.
Proc.Natl.Acad.Sci.USA, 109, 2012
4EUT
DownloadVisualize
BU of 4eut by Molmil
Structure of BX-795 Complexed with Unphosphorylated Human TBK1 Kinase-ULD Domain
分子名称: IODIDE ION, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, SULFATE ION, ...
著者Ma, X, Helgason, E, Phung, Q.T, Quan, C.L, Iyer, R.S, Lee, M.W, Bowman, K.K, Starovasnik, M.A, Dueber, E.C.
登録日2012-04-25
公開日2012-05-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DKE
DownloadVisualize
BU of 4dke by Molmil
Crystal Structure of Human Interleukin-34 Bound to FAb1.1
分子名称: FAb1.1 Heavy Chain, FAb1.1 Light Chain, Interleukin-34, ...
著者Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
4DKF
DownloadVisualize
BU of 4dkf by Molmil
Crystal Structure of Human Interleukin-34 Bound to FAb2
分子名称: FAb2 Heavy Chain, FAb2 Light Chain, Interleukin-34, ...
著者Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
4DKC
DownloadVisualize
BU of 4dkc by Molmil
Crystal Structure of Human Interleukin-34
分子名称: Interleukin-34, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Ma, X, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
4DKD
DownloadVisualize
BU of 4dkd by Molmil
Crystal Structure of Human Interleukin-34 Bound to Human CSF-1R
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, ...
著者Ma, X, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
3P9W
DownloadVisualize
BU of 3p9w by Molmil
Crystal structure of an engineered human autonomous VH Domain in complex with VEGF
分子名称: Vascular endothelial growth factor A, human VEGF
著者Ma, X, Wiesmann, C.
登録日2010-10-18
公開日2012-04-18
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Design of Synthetic Autonomous VH Domain Libraries and Structural Analysis of a VH Domain Bound to Vascular Endothelial Growth Factor.
J.Mol.Biol., 425, 2013
6IZT
DownloadVisualize
BU of 6izt by Molmil
Crystal structure of Haemophilus Influenzae BamA POTRA3-5
分子名称: Outer membrane protein assembly factor BamA
著者Ma, X, Wang, Q, Li, Y, Tan, P, Wu, H, Wang, P, Dong, X, Hong, L, Meng, G.
登録日2018-12-20
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献How BamA recruits OMP substratesviapoly-POTRAs domain.
Faseb J., 33, 2019
6IZS
DownloadVisualize
BU of 6izs by Molmil
Crystal structure of Haemophilus influenzae BamA POTRA4
分子名称: Outer membrane protein assembly factor BamA
著者Ma, X, Wang, Q, Li, Y, Tan, P, Wu, H, Wang, P, Dong, X, Hong, L, Meng, G.
登録日2018-12-20
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献How BamA recruits OMP substratesviapoly-POTRAs domain.
Faseb J., 33, 2019
6J09
DownloadVisualize
BU of 6j09 by Molmil
Crystal structure of Haemophilus Influenzae BamA POTRA1-4
分子名称: Outer membrane protein assembly factor BamA
著者Ma, X, Wang, Q, Li, Y, Tan, P, Wu, H, Wang, P, Dong, X, Hong, L, Meng, G.
登録日2018-12-21
公開日2019-10-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献How BamA recruits OMP substratesviapoly-POTRAs domain.
Faseb J., 33, 2019
5WL0
DownloadVisualize
BU of 5wl0 by Molmil
Co-crystal structure of Influenza A H3N2 PB2 (241-741) bound to VX-787
分子名称: (2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, DI(HYDROXYETHYL)ETHER, Polymerase basic protein 2
著者Ma, X, Shia, S.
登録日2017-07-25
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for therapeutic inhibition of influenza A polymerase PB2 subunit.
Sci Rep, 7, 2017

225158

件を2024-09-18に公開中

PDB statisticsPDBj update infoContact PDBjnumon