6P88
E.coli LpxD in complex with compound 6
Summary for 6P88
Entry DOI | 10.2210/pdb6p88/pdb |
Descriptor | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, MAGNESIUM ION, N-{3-[(furan-2-carbonyl)amino]phenyl}-2,3-dihydro-1,4-benzodioxine-6-carboxamide, ... (5 entities in total) |
Functional Keywords | lps synthesis, transferase, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Escherichia coli |
Total number of polymer chains | 3 |
Total formula weight | 109495.82 |
Authors | |
Primary citation | Ma, X.,Prathapam, R.,Wartchow, C.,Chie-Leon, B.,Ho, C.M.,De Vicente, J.,Han, W.,Li, M.,Lu, Y.,Ramurthy, S.,Shia, S.,Steffek, M.,Uehara, T. Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis. Acs Infect Dis., 6:1480-1489, 2020 Cited by PubMed: 31402665DOI: 10.1021/acsinfecdis.9b00127 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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