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6P86

E.coli LpxD in complex with compound 4.1

Summary for 6P86
Entry DOI10.2210/pdb6p86/pdb
DescriptorUDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, MAGNESIUM ION, N-[(4-ethylphenyl)methyl]-2-[(6aR)-6-oxo-3-(pyrrolidine-1-carbonyl)-6,6a,7,8,9,10-hexahydro-5H-pyrido[1,2-a]quinoxalin-5-yl]acetamide, ... (5 entities in total)
Functional Keywordslps synthesis, transferase
Biological sourceEscherichia coli
Total number of polymer chains3
Total formula weight109606.06
Authors
Ma, X.,Shia, S. (deposition date: 2019-06-06, release date: 2019-08-28, Last modification date: 2023-10-11)
Primary citationMa, X.,Prathapam, R.,Wartchow, C.,Chie-Leon, B.,Ho, C.M.,De Vicente, J.,Han, W.,Li, M.,Lu, Y.,Ramurthy, S.,Shia, S.,Steffek, M.,Uehara, T.
Structural and Biological Basis of Small Molecule Inhibition ofEscherichia coliLpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis.
Acs Infect Dis., 6:1480-1489, 2020
Cited by
PubMed: 31402665
DOI: 10.1021/acsinfecdis.9b00127
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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