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2PZR
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BU of 2pzr by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome
Descriptor: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
Authors:Chen, H, Mohammadi, M.
Deposit date:2007-05-18
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PSQ
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BU of 2psq by Molmil
Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain
Descriptor: Fibroblast growth factor receptor 2, SULFATE ION
Authors:Chen, H, Mohammadi, M.
Deposit date:2007-05-07
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PVY
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BU of 2pvy by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome.
Descriptor: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
Authors:Chen, H, Mohammadi, M.
Deposit date:2007-05-10
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PY3
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BU of 2py3 by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565G Mutation Responsible for Pfeiffer Syndrome
Descriptor: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Chen, H, Mohammadi, M.
Deposit date:2007-05-15
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PZP
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BU of 2pzp by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K526E Mutation Responsible for Crouzon Syndrome
Descriptor: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Chen, H, Mohammadi, M.
Deposit date:2007-05-18
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2Q0B
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BU of 2q0b by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565A Mutation Responsible for Pfeiffer Syndrome
Descriptor: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
Authors:Chen, H, Mohammadi, M.
Deposit date:2007-05-21
Release date:2007-09-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2RFH
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BU of 2rfh by Molmil
Crystal Structure Analysis of CPA-2-benzyl-3-nitropropanoic acid complex
Descriptor: (2R)-2-benzyl-3-nitropropanoic acid, Carboxypeptidase A1, ZINC ION
Authors:Wang, S.-F, Zeng, Z.-H.
Deposit date:2007-09-29
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A
Bioorg.Med.Chem., 16, 2008
6IEW
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BU of 6iew by Molmil
The crystal structure of the dNxf2 UBA domain in complex with Panoramix
Descriptor: Fusion protein of Nuclear RNA export factor 2 and Protein panoramix, GLYCEROL
Authors:Huang, Y, Cheng, S.
Deposit date:2018-09-17
Release date:2019-08-21
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation.
Nat.Cell Biol., 21, 2019
6IHJ
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BU of 6ihj by Molmil
Crystal structure of Drosophila Nxf1 NTF2 domain in complex with Nxt1/p15
Descriptor: NTF2-related export protein, Nuclear RNA export factor 1
Authors:Huang, Y, Yuan, X.
Deposit date:2018-09-30
Release date:2019-08-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation.
Nat.Cell Biol., 21, 2019
6S1K
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BU of 6s1k by Molmil
E. coli Core Signaling Unit, carrying QQQQ receptor mutation
Descriptor: CheW, Chemotaxis protein CheA, Methyl-accepting chemotaxis protein I
Authors:Cassidy, C.K.
Deposit date:2019-06-18
Release date:2020-01-22
Method:ELECTRON MICROSCOPY (8.38 Å)
Cite:Structure and dynamics of the E. coli chemotaxis core signaling complex by cryo-electron tomography and molecular simulations.
Commun Biol, 3, 2020
6KZ4
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BU of 6kz4 by Molmil
YebT domain 5-7
Descriptor: Intermembrane transport protein YebT
Authors:Wang, H.W, Liu, C, Zhang, L.
Deposit date:2019-09-23
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM Structure of a Bacterial Lipid Transporter YebT.
J.Mol.Biol., 432, 2020
6KZ3
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BU of 6kz3 by Molmil
YebT domain1-4
Descriptor: Intermembrane transport protein YebT
Authors:Wang, H.W, Liu, C, Zhang, L.
Deposit date:2019-09-23
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM Structure of a Bacterial Lipid Transporter YebT.
J.Mol.Biol., 432, 2020
6LBH
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BU of 6lbh by Molmil
Cryo-EM structure of the MgtE Mg2+ channel under Mg2+-free conditions
Descriptor: Fab heavy chain, Fab light chain, Magnesium transporter MgtE
Authors:Hattori, M, Jin, F.
Deposit date:2019-11-14
Release date:2021-04-14
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The structure of MgtE in the absence of magnesium provides new insights into channel gating.
Plos Biol., 19, 2021
3GZN
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BU of 3gzn by Molmil
Structure of NEDD8-activating enzyme in complex with NEDD8 and MLN4924
Descriptor: NEDD8, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1 regulatory subunit, ...
Authors:Sintchak, M.D.
Deposit date:2009-04-07
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ.
Mol.Cell, 37, 2010
7YDW
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BU of 7ydw by Molmil
Crystal structure of the MPND-DNA complex
Descriptor: DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MPN domain-containing protein
Authors:Yang, M, Chen, Z.
Deposit date:2022-07-04
Release date:2023-02-15
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structures of MPND Reveal the Molecular Recognition of Nucleosomes.
Int J Mol Sci, 24, 2023
7YDT
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BU of 7ydt by Molmil
Crystal structure of mouse MPND
Descriptor: MPN domain containing protein
Authors:Yang, M, Chen, Z.
Deposit date:2022-07-04
Release date:2023-02-15
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (2.055 Å)
Cite:Structures of MPND Reveal the Molecular Recognition of Nucleosomes.
Int J Mol Sci, 24, 2023
5FAD
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BU of 5fad by Molmil
SAH complex with aKMT from the hyperthermophilic archaeon Sulfolobus islandicus
Descriptor: MAGNESIUM ION, Ribosomal protein L11 methyltransferase, putative, ...
Authors:Ouyang, S.
Deposit date:2015-12-11
Release date:2016-06-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:aKMT Catalyzes Extensive Protein Lysine Methylation in the Hyperthermophilic Archaeon Sulfolobus islandicus but is Dispensable for the Growth of the Organism
Mol.Cell Proteomics, 15, 2016
5FA8
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BU of 5fa8 by Molmil
SAM complex with aKMT from the hyperthermophilic archaeon Sulfolobus islandicu
Descriptor: MAGNESIUM ION, Ribosomal protein L11 methyltransferase, putative, ...
Authors:Ouyang, S.
Deposit date:2015-12-11
Release date:2016-06-29
Last modified:2016-09-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:aKMT Catalyzes Extensive Protein Lysine Methylation in the Hyperthermophilic Archaeon Sulfolobus islandicus but is Dispensable for the Growth of the Organism
Mol.Cell Proteomics, 15, 2016
4JHD
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BU of 4jhd by Molmil
Crystal Structure of an Actin Dimer in Complex with the Actin Nucleator Cordon-Bleu
Descriptor: Actin-5C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Chen, X, Ni, F, Wang, Q.
Deposit date:2013-03-04
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural basis of actin filament nucleation by tandem w domains.
Cell Rep, 3, 2013
7YJI
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BU of 7yji by Molmil
Crystal structure of Lpg1083 from Legionella pneumophila
Descriptor: ACETATE ION, T4SS effector Lpg1083
Authors:Ge, H, Gao, J, Chen, X.
Deposit date:2022-07-20
Release date:2023-06-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The bacterial effector SidN/Lpg1083 promotes cell death by targeting Lamin-B2.
J Mol Cell Biol, 15, 2023
7VD4
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BU of 7vd4 by Molmil
Crystal structure of BPTF-BRD with ligand TP248 bound
Descriptor: 6-[4-[3-(dimethylamino)propoxy]phenyl]-N-methyl-2-methylsulfonyl-pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF
Authors:Lu, T, Lu, H.B.
Deposit date:2021-09-06
Release date:2022-09-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.85659146 Å)
Cite:Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold.
Bioorg.Chem., 123, 2022
7WQG
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BU of 7wqg by Molmil
Bovin Alpha-lactalbumin binding with zinc ions
Descriptor: Alpha-lactalbumin, ZINC ION
Authors:Li, T, Zhang, T.
Deposit date:2022-01-25
Release date:2022-08-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Zinc binding strength of proteins dominants zinc uptake in Caco-2 cells.
Rsc Adv, 12, 2022
7XQ0
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BU of 7xq0 by Molmil
Structure of hSLC19A1+3'3'-CDA
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Reduced folate transporter
Authors:Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P.
Deposit date:2022-05-06
Release date:2022-10-05
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Recognition of cyclic dinucleotides and folates by human SLC19A1.
Nature, 612, 2022
7XPZ
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BU of 7xpz by Molmil
Structure of Apo-hSLC19A1
Descriptor: Reduced folate transporter
Authors:Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P.
Deposit date:2022-05-06
Release date:2022-10-05
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Recognition of cyclic dinucleotides and folates by human SLC19A1.
Nature, 612, 2022
7XQ2
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BU of 7xq2 by Molmil
Structure of hSLC19A1+2'3'-cGAMP
Descriptor: Reduced folate transporter, cGAMP
Authors:Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P.
Deposit date:2022-05-06
Release date:2022-10-05
Last modified:2022-12-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Recognition of cyclic dinucleotides and folates by human SLC19A1.
Nature, 612, 2022

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