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7D8C
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BU of 7d8c by Molmil
Crystal structure of the Cas12i1-crRNA binary complex
分子名称: 12i1, CITRIC ACID, RNA (3-MER), ...
著者Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y.
登録日2020-10-07
公開日2021-05-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Nat Commun, 12, 2021
7D3J
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BU of 7d3j by Molmil
Crystal structure of the Cas12i1 R-loop complex after target DNA cleavage
分子名称: 12i1-WT, CITRIC ACID, DNA (23-MER), ...
著者Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y.
登録日2020-09-19
公開日2021-05-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Nat Commun, 12, 2021
7EU9
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BU of 7eu9 by Molmil
Crystal structure of the selenomethionine(SeMet)-derived Cas12i1 R-loop complex before target DNA cleavage
分子名称: CITRIC ACID, Cas12i1 D647A mutant, DNA (24-MER), ...
著者Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y.
登録日2021-05-16
公開日2021-05-26
最終更新日2021-06-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Nat Commun, 12, 2021
7FGH
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BU of 7fgh by Molmil
Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GMP
分子名称: N7-METHYL-GUANOSINE-5'-MONOPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ...
著者Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H.
登録日2021-07-27
公開日2022-07-27
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (2.18 Å)
主引用文献Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
7FGG
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BU of 7fgg by Molmil
Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GTP
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H.
登録日2021-07-27
公開日2022-07-27
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (2.19 Å)
主引用文献Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
7FGI
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BU of 7fgi by Molmil
Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7Gppp-AU
分子名称: GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ...
著者Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H.
登録日2021-07-27
公開日2022-07-27
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Molecular basis of specific viral RNA recognition and 5'-end capping by the Chikungunya virus nsP1.
Cell Rep, 40, 2022
5YOF
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BU of 5yof by Molmil
Crystal structure of zika virus NS3 protease in complex with a dipeptide inhibitor
分子名称: (S)-2-acetamido-6-amino-N-((S)-5-guanidino-1-oxopentan-2-yl)hexanamide, NS2B cofactor, NS3 Protease
著者Phoo, W.W, Zhang, Z.Z.
登録日2017-10-27
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
Structure, 26, 2018
5YOD
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BU of 5yod by Molmil
Crystal structure of zika virus NS3 protease in complex with a small molecule inhibitor
分子名称: BENZOIC ACID, NS2B cofactor, NS3 protease
著者Phoo, W.W, Zhang, Z.Z.
登録日2017-10-27
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
Structure, 26, 2018
5YVJ
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BU of 5yvj by Molmil
Crystal structure of full length NS2B47-NS3 (gD4NS2BNS3) from Dengue virus 4 in open conformation
分子名称: GLYCEROL, Genome polyprotein
著者Phoo, W.W, El Sahili, A.
登録日2017-11-26
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.508 Å)
主引用文献Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5YVV
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BU of 5yvv by Molmil
Crystal structure of full length NS3 protein (gD4NS2BNS3) from DENV4 in closed conformation
分子名称: Genome polyprotein
著者PHOO, W.W, Sahili, A.E.
登録日2017-11-27
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.097 Å)
主引用文献Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5YVW
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BU of 5yvw by Molmil
Crystal structure of full length NS3 protein (eD4NS2BNS3) from DENV4 in closed conformation
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Genome polyprotein
著者PHOO, W.W, El Sahili, A.
登録日2017-11-27
公開日2018-12-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5ZOB
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BU of 5zob by Molmil
Crystal structure of Zika NS3 protease with 4-guanidinomethyl-phenylacetyl-Arg-Arg-Arg-4-amidinobenzylamide
分子名称: 4-guanidinomethyl-phenylacetyl-Arg-Arg-Arg-4-amidinobenzylamide, NS3 protease, Serine protease subunit NS2B
著者Phoo, W.W, Wirawan, M.
登録日2018-04-12
公開日2018-10-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors.
Antiviral Res., 160, 2018
5YW1
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BU of 5yw1 by Molmil
Crystal structure of full length NS3 protein (eD4NS2BNS3) in complex with Bovine Pancreatic Trypsin Inhibitor
分子名称: FLAVIVIRUS_NS2B, PTI protein, Peptidase S7
著者Phoo, W.W, El Sahili, A.
登録日2017-11-28
公開日2019-01-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5YVU
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BU of 5yvu by Molmil
Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
分子名称: GLYCEROL, Genome polyprotein, Pancreatic trypsin inhibitor
著者Phoo, W.W, El Sahili, A.
登録日2017-11-27
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.491 Å)
主引用文献Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5YVY
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BU of 5yvy by Molmil
Crystal structure of unlinked full length NS3 protein (eD4NS2BNS3) from DENV4 in closed conformation
分子名称: Genome polyprotein
著者PHOO, W.W, El Sahili, A.
登録日2017-11-27
公開日2018-11-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5ZMQ
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BU of 5zmq by Molmil
Crystal structure of Zika NS3 protease with phenylacetyl-Lys-Lys-Arg-COOH inhibitor
分子名称: Serine protease NS3, Serine protease subunit NS2B, peptide PAC-DLY-DLY-DAR
著者Phoo, W.W, Wirawan, M.
登録日2018-04-05
公開日2018-10-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.987 Å)
主引用文献Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors.
Antiviral Res., 160, 2018
5ZMS
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BU of 5zms by Molmil
Crystal structure of Zika NS3 protease in complex with 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H
分子名称: 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H, NS3 protease, Serine protease subunit NS2B
著者Phoo, W.W, Wirawan, M.
登録日2018-04-05
公開日2018-10-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors.
Antiviral Res., 160, 2018
7C2P
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BU of 7c2p by Molmil
Structure of Egk Peptide
分子名称: Plant defensing Egk
著者El Sahili, A.
登録日2020-05-08
公開日2020-09-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin.
Acs Pharmacol Transl Sci, 3, 2020
7VMV
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BU of 7vmv by Molmil
Crystal structure of Dengue NS2B-NS3 Protease after secondary cleavage
分子名称: Core protein
著者Quek, J.P.
登録日2021-10-09
公開日2022-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.351 Å)
主引用文献Dynamic Interactions of Post Cleaved NS2B Cofactor and NS3 Protease Identified by Integrative Structural Approaches.
Viruses, 14, 2022
7DOC
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BU of 7doc by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 5
分子名称: 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, Core protein, Genome polyprotein, ...
著者Quek, J.P.
登録日2020-12-14
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease.
Acs Med.Chem.Lett., 12, 2021
7FAV
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BU of 7fav by Molmil
Crystal Structure of Rubella Protease
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Quek, J.P.
登録日2021-07-07
公開日2022-07-13
最終更新日2022-09-14
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold.
J.Biol.Chem., 298, 2022

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件を2024-05-22に公開中

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