5CN0
| Artificial HIV fusion inhibitor AP2 fused to the C-terminus of gp41 NHR | 分子名称: | DI(HYDROXYETHYL)ETHER, Envelope glycoprotein,AP2, MAGNESIUM ION | 著者 | Zhu, Y, Ye, S, Zhang, R. | 登録日 | 2015-07-17 | 公開日 | 2015-09-16 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy. Sci Rep, 5, 2015
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5CMU
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5VAG
| Crystal structure of H7-specific antibody m826 in complex with the HA1 domain of hemagglutinin from H7N9 influenza virus | 分子名称: | 1,2-ETHANEDIOL, Heavy chain of antibody m826, Hemagglutinin, ... | 著者 | Song, H, Ying, T, Ji, X. | 登録日 | 2017-03-26 | 公開日 | 2017-12-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin. Cell Host Microbe, 22, 2017
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5H0N
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5H3D
| Helical structure of membrane tubules decorated by ACAP1 (BARPH doamin) protein by cryo-electron microscopy and MD simulation | 分子名称: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 | 著者 | Chan, C, Pang, X.Y, Zhang, Y, Sun, F, Fan, J. | 登録日 | 2016-10-22 | 公開日 | 2019-01-16 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | ACAP1 assembles into an unusual protein lattice for membrane deformation through multiple stages. Plos Comput.Biol., 15, 2019
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6L2G
| Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase | 分子名称: | Acetyl-CoA-acetyltransferase, putative | 著者 | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | 登録日 | 2019-10-03 | 公開日 | 2020-02-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target. Appl.Environ.Microbiol., 86, 2020
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6L2C
| Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase in complex with CoA | 分子名称: | Acetyl-CoA-acetyltransferase, putative, COENZYME A | 著者 | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | 登録日 | 2019-10-03 | 公開日 | 2020-02-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target. Appl.Environ.Microbiol., 86, 2020
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6M4C
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8CGP
| Insulin regulated aminopeptidase (IRAP) in complex with an allosteric aryl sulfonamide inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mpakali, A, Stratikos, E, Giastas, P. | 登録日 | 2023-02-06 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase. J.Mol.Biol., 436, 2024
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8CGW
| Insulin-regulated aminopeptidase (IRAP) in complex with an allosteric benzopyran-based inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mpakali, A, Stratikos, E, Giastas, P. | 登録日 | 2023-02-06 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase. J.Mol.Biol., 436, 2024
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7D0P
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7D0S
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7D0Q
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7D0O
| Crystal structure of human HBO1-BRPF2 in apo form | 分子名称: | 1,2-ETHANEDIOL, BRD1 protein, Histone acetyltransferase KAT7, ... | 著者 | Li, W, Ding, J. | 登録日 | 2020-09-11 | 公開日 | 2021-07-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | HBO1 is a versatile histone acyltransferase critical for promoter histone acylations. Nucleic Acids Res., 49, 2021
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7D0R
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7WQV
| Crystal structure of a neutralizing monoclonal antibody (Ab08) in complex with SARS-CoV-2 receptor-binding domain (RBD) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ab08, ... | 著者 | Zha, J, Meng, L, Zhang, X, Li, D. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy. Plos Pathog., 19, 2023
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7FEM
| SARS-CoV-2 B.1.1.7 S-ACE2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Wen, Z.L, Zhu, Y, Sun, F. | 登録日 | 2021-07-21 | 公開日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B.1.1.7 variant (Alpha). Cell Discov, 7, 2021
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7FET
| SARS-CoV-2 B.1.1.7 Spike Glycoprotein trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Wen, Z.L, Zhu, Y, Sun, F. | 登録日 | 2021-07-21 | 公開日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B.1.1.7 variant (Alpha). Cell Discov, 7, 2021
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7CT5
| S protein of SARS-CoV-2 in complex bound with T-ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Guo, L, Bi, W.W, Zhang, Y.Y, Yan, R.H, Li, Y.N, Zhou, Q, Dang, B.B. | 登録日 | 2020-08-18 | 公開日 | 2020-11-18 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection. Cell Res., 31, 2021
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5TKE
| Crystal Structure of Eukaryotic Hydrolase | 分子名称: | O-GlcNAcase: chimera construct | 著者 | Li, B, Jiang, J. | 登録日 | 2016-10-06 | 公開日 | 2017-03-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.481 Å) | 主引用文献 | Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode. Nat. Struct. Mol. Biol., 24, 2017
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5TUW
| Crystal structure of Orange Carotenoid Protein with partial loss of 3'OH Echinenone chromophore | 分子名称: | (3'R)-3'-hydroxy-beta,beta-caroten-4-one, GLYCEROL, Orange carotenoid-binding protein | 著者 | Yang, X, Bandara, S, Ren, Z. | 登録日 | 2016-11-07 | 公開日 | 2017-06-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | Photoactivation mechanism of a carotenoid-based photoreceptor. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5TV0
| crystal structure and light induced structural changes in orange carotenoid protein bound with 3 'OH echinenone | 分子名称: | (3'R)-3'-hydroxy-beta,beta-caroten-4-one, GLYCEROL, Orange carotenoid-binding protein | 著者 | Yang, X, Bandara, S, Ren, Z. | 登録日 | 2016-11-07 | 公開日 | 2017-06-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.648 Å) | 主引用文献 | Photoactivation mechanism of a carotenoid-based photoreceptor. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5TUX
| crystal structure and light induced structural changes in orange carotenoid protein bound with echinenone | 分子名称: | GLYCEROL, Orange carotenoid-binding protein, beta,beta-caroten-4-one | 著者 | Yang, X, Bandara, S, Ren, Z. | 登録日 | 2016-11-07 | 公開日 | 2017-06-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Photoactivation mechanism of a carotenoid-based photoreceptor. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7WJY
| Omicron spike trimer with 6m6 antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | 登録日 | 2022-01-08 | 公開日 | 2022-07-13 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding. Cell Res., 32, 2022
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7WK0
| Local refine of Omicron spike bitrimer with 6m6 antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ... | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | 登録日 | 2022-01-08 | 公開日 | 2022-07-13 | 最終更新日 | 2022-09-14 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding. Cell Res., 32, 2022
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