5CN0

Artificial HIV fusion inhibitor AP2 fused to the C-terminus of gp41 NHR

Summary for 5CN0

• Entry DOI: 10.2210/pdb5cn0/pdb
• Related: 5CMU 5CMZ
• Descriptor: Envelope glycoprotein,AP2, MAGNESIUM ION, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
• Functional Keywords: enfuvirtide, hiv fusion inhibitor, ap2, gp41, 6-hb, viral protein
• Biological source: Human immunodeficiency virus 1 (HIV1); More
• Total number of polymer chains: 1
• Total formula weight: 8741.31

Authors

Zhu, Y.,Ye, S.,Zhang, R. (deposition date: 2015-07-17, release date: 2015-09-16, Last modification date: 2024-03-20)

• Primary citation: Zhu, X.,Zhu, Y.,Ye, S.,Wang, Q.,Xu, W.,Su, S.,Sun, Z.,Yu, F.,Liu, Q.,Wang, C.,Zhang, T.,Zhang, Z.,Zhang, X.,Xu, J.,Du, L.,Liu, K.,Lu, L.,Zhang, R.,Jiang, S.; Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy.; Sci Rep, 5:13028-13028, 2015; PubMed: 26286358; DOI: 10.1038/srep13028

Experimental method

X-RAY DIFFRACTION (1.901 Å)