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2BIR
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BU of 2bir by Molmil
ADDITIVITY OF SUBSTRATE BINDING IN RIBONUCLEASE T1 (Y42A MUTANT)
Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1
Authors:Doumen, J, Steyaert, J, Loverix, S.
Deposit date:1996-12-03
Release date:1997-06-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Additivity of protein-guanine interactions in ribonuclease T1.
J.Biol.Chem., 272, 1997
5MJ4
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BU of 5mj4 by Molmil
INTERLEUKIN-23 COMPLEX WITH AN ANTAGONISTIC ALPHABODY, CRYSTAL FORM 2
Descriptor: ALPHABODY MA12, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ...
Authors:Desmet, J, Verstraete, K, Bloch, Y, Lorent, E, Wen, Y, Devreese, B, Vandenbroucke, K, Loverix, S, Hettmann, T, Deroo, S, Somers, K, Henderikx, P, Lasters, I, Savvides, S.
Deposit date:2016-11-29
Release date:2017-01-11
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:STRUCTURAL BASIS OF IL-23 ANTAGONISM BY AN ALPHABODY PROTEIN
Nature Communications, 5, 2014
1R4F
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BU of 1r4f by Molmil
Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma vivax: Trp260Ala Mutant In Complex With 3-Deaza-Adenosine
Descriptor: 3-DEAZA-ADENOSINE, CALCIUM ION, IAG-nucleoside hydrolase
Authors:Versees, W, Loverix, S, Vandemeulebroucke, A, Geerlings, P, Steyaert, J.
Deposit date:2003-10-06
Release date:2004-04-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Leaving group activation by aromatic stacking: an alternative to general Acid catalysis.
J.Mol.Biol., 338, 2004
5MJ3
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BU of 5mj3 by Molmil
INTERLEUKIN-23 COMPLEX WITH AN ANTAGONISTIC ALPHABODY, CRYSTAL FORM 1
Descriptor: ALPHABODY MA12, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ...
Authors:Desmet, J, Verstraete, K, Bloch, Y, Lorent, E, Wen, Y, Devreese, B, Vandenbroucke, K, Loverix, S, Hettmann, T, Deroo, S, Somers, K, Hendrikx, P, Lasters, I, Savvides, S.N.
Deposit date:2016-11-29
Release date:2017-01-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural Basis Of Il-23 Antagonism By An Alphabody Protein Scaffold.
Nat Commun, 5, 2014
1LOY
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BU of 1loy by Molmil
X-ray structure of the H40A/E58A mutant of Ribonuclease T1 complexed with 3'-guanosine monophosphate
Descriptor: CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, Guanyl-specific ribonuclease T1
Authors:Mignon, P, Steyaert, J, Loris, R, Geerlings, P, Loverix, S.
Deposit date:2002-05-07
Release date:2002-08-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A nucleophile activation dyad in ribonucleases. A combined X-ray crystallographic/ab initio quantum chemical study
J.Biol.Chem., 277, 2002
1LOW
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BU of 1low by Molmil
X-ray structure of the H40A mutant of Ribonuclease T1 complexed with 3'-guanosine monophosphate
Descriptor: CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, Guanyl-specific ribonuclease T1
Authors:Mignon, P, Steyaert, J, Loris, R, Geerlings, P, Loverix, S.
Deposit date:2002-05-07
Release date:2002-08-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A nucleophile activation dyad in ribonucleases. A combined X-ray crystallographic/ab initio quantum chemical study
J.Biol.Chem., 277, 2002
1LOV
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BU of 1lov by Molmil
X-ray structure of the E58A mutant of Ribonuclease T1 complexed with 3'-guanosine monophosphate
Descriptor: CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, Guanyl-specific ribonuclease T1
Authors:Mignon, P, Steyaert, J, Loris, R, Geerlings, P, Loverix, S.
Deposit date:2002-05-07
Release date:2002-08-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A nucleophile activation dyad in ribonucleases. A combined X-ray crystallographic/ab initio quantum chemical study
J.Biol.Chem., 277, 2002
6ZL1
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BU of 6zl1 by Molmil
Crystal structure of human serum albumin in complex with the MCL-1 neutralizing Alphabody CMPX-383B
Descriptor: Albumin, CMPX-383B
Authors:Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I.
Deposit date:2020-06-30
Release date:2021-04-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.272 Å)
Cite:Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Sci Adv, 7, 2021
6ZIE
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BU of 6zie by Molmil
Crystal structure of MCL-1 in complex with a neutralizing Alphabody CMPX-383B
Descriptor: CMPX-383B, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION
Authors:Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I.
Deposit date:2020-06-25
Release date:2021-04-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Sci Adv, 7, 2021

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