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4X9E
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BU of 4x9e by Molmil
DEOXYGUANOSINETRIPHOSPHATE TRIPHOSPHOHYDROLASE from Escherichia coli with two DNA effector molecules
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, MAGNESIUM ION, RNA (5'-R(P*CP*CP*C)-3')
著者Singh, D, Gawel, D, Itsko, M, Krahn, J.M, London, R.E, Schaaper, R.M.
登録日2014-12-11
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of Escherichia coli dGTP Triphosphohydrolase: A HEXAMERIC ENZYME WITH DNA EFFECTOR MOLECULES.
J.Biol.Chem., 290, 2015
4XDS
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BU of 4xds by Molmil
Deoxyguanosinetriphosphate Triphosphohydrolase from Escherichia coli with Nickel
分子名称: Deoxyguanosinetriphosphate triphosphohydrolase, NICKEL (II) ION, SULFATE ION
著者Singh, D, Gawel, D, Itsko, M, Krahn, J.M, London, R.E, Schaaper, R.M.
登録日2014-12-19
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.354 Å)
主引用文献Structure of Escherichia coli dGTP Triphosphohydrolase: A HEXAMERIC ENZYME WITH DNA EFFECTOR MOLECULES.
J.Biol.Chem., 290, 2015
4ZCE
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BU of 4zce by Molmil
Crystal Structure of the dust mite allergen Der p 23 from Dermatophagoides pteronyssinus
分子名称: 1,2-ETHANEDIOL, Dust mite allergen
著者Pedersen, L.C, Mueller, G.A, Randall, T.A, Glesner, J, Perera, L, Edwards, L.L, Chapman, M.D, London, R.E, Pomes, A.
登録日2015-04-15
公開日2015-11-25
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Serological, genomic and structural analyses of the major mite allergen Der p 23.
Clin Exp Allergy, 46, 2016
6VCJ
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BU of 6vcj by Molmil
Crystal structure of hsDHFR in complex with NADP+, DAP, and R-naproxen
分子名称: (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid, Dihydrofolate reductase, FOLIC ACID, ...
著者Pedersen, L.C, London, R.E, Gabel, S.A, Krahn, J.M, DeRose, E.F.
登録日2019-12-21
公開日2020-10-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.
J.Med.Chem., 63, 2020
4JRB
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BU of 4jrb by Molmil
Structure of Cockroach Allergen Bla g 1 Tandem Repeat as a EGFP fusion
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CHLORIDE ION, DODECANE, ...
著者Mueller, G.A, Pedersen, L.C, Lih, F.B, Glesner, J, Moon, A.F, Chapman, M.D, Tomer, K, London, R.E.
登録日2013-03-21
公開日2013-07-24
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.414 Å)
主引用文献The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment.
J.Allergy Clin.Immunol., 132, 2013
4EHQ
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BU of 4ehq by Molmil
Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+/Calmodulin Displays a Unique Binding Mode
分子名称: CALCIUM ION, Calcium release-activated calcium channel protein 1, Calmodulin, ...
著者Liu, Y, Zheng, X, Mueller, G.A, Sobhany, M, DeRose, E.F, Zhang, Y, London, R.E, Birnbaumer, L.
登録日2012-04-03
公開日2012-11-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9005 Å)
主引用文献Crystal structure of calmodulin binding domain of orai1 in complex with ca2+*calmodulin displays a unique binding mode.
J.Biol.Chem., 287, 2012
4KSE
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BU of 4kse by Molmil
Crystal structure of a HIV p51 (219-230) deletion mutant
分子名称: 1,2-ETHANEDIOL, HIV p51 subunit
著者Zheng, X, Mueller, G.A, Derose, E.F, Pedersen, L.C, Gabel, S.A, Cuneo, M.J, Krahn, J.M, London, R.E.
登録日2013-05-17
公開日2014-08-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.677 Å)
主引用文献Selective unfolding of one Ribonuclease H domain of HIV reverse transcriptase is linked to homodimer formation.
Nucleic Acids Res., 42, 2014
2A31
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BU of 2a31 by Molmil
Trypsin in complex with borate
分子名称: BORATE ION, CALCIUM ION, GUANIDINE-3-PROPANOL, ...
著者Transue, T.R, Gabel, S.A, London, R.E.
登録日2005-06-23
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献NMR and crystallographic characterization of adventitious borate binding by trypsin.
Bioconjug.Chem., 17, 2006
2A32
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Trypsin in complex with benzene boronic acid
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, BORATE ION, CALCIUM ION, ...
著者Transue, T.R, Gabel, S.A, London, R.E.
登録日2005-06-23
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献NMR and crystallographic characterization of adventitious borate binding by trypsin.
Bioconjug.Chem., 17, 2006
5DZM
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BU of 5dzm by Molmil
HIV-1 Reverse Transcriptase RH domain
分子名称: Ribonuclease H
著者Pedersen, L.C, London, R.E, Gabel, S.A, Zheng, X.H.
登録日2015-09-25
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Unfolding the HIV-1 reverse transcriptase RNase H domain - how to lose a molecular tug-of-war.
Nucleic Acids Res., 44, 2016
5E6Q
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BU of 5e6q by Molmil
Importin alpha binding to XRCC1 NLS peptide
分子名称: CHLORIDE ION, DNA repair protein XRCC1 NLS peptide, GLYCEROL, ...
著者Pedersen, L.C, Kirby, T.W, Gassman, N.R, Smith, C.E, Gabel, S.A, Sobhany, M, Wilson, S.H, London, R.E.
登録日2015-10-10
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.305 Å)
主引用文献Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS.
Sci Rep, 5, 2015
3H4Z
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BU of 3h4z by Molmil
Crystal Structure of an MBP-Der p 7 fusion protein
分子名称: Maltose-binding periplasmic protein fused with Allergen DERP7, SODIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pedersen, L.C, Mueller, G.A, London, R.E.
登録日2009-04-21
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins.
J.Allergy Clin.Immunol., 125, 2010
3K75
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BU of 3k75 by Molmil
X-ray crystal structure of reduced XRCC1 bound to DNA pol beta catalytic domain
分子名称: DNA polymerase beta, DNA repair protein XRCC1
著者Cuneo, M.J, London, R.E.
登録日2009-10-12
公開日2010-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
Proc.Natl.Acad.Sci.USA, 107, 2010
3K77
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BU of 3k77 by Molmil
X-ray crystal structure of XRCC1
分子名称: DNA repair protein XRCC1
著者Cuneo, M.J, London, R.E.
登録日2009-10-12
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.597 Å)
主引用文献Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
Proc.Natl.Acad.Sci.USA, 107, 2010
2HTF
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BU of 2htf by Molmil
The solution structure of the BRCT domain from human polymerase reveals homology with the TdT BRCT domain
分子名称: DNA polymerase mu
著者DeRose, E.F, Clarkson, M.W, Gilmore, S.A, Ramsden, D.A, Mueller, G.A, London, R.E, Lee, A.L.
登録日2006-07-25
公開日2007-02-27
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining.
Biochemistry, 46, 2007
2IDO
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BU of 2ido by Molmil
Structure of the E. coli Pol III epsilon-Hot proofreading complex
分子名称: 1,2-ETHANEDIOL, DNA polymerase III epsilon subunit, Hot protein, ...
著者Kirby, T.W, Harvey, S, DeRose, E.F, Chalov, S, Chikova, A.K, Perrino, F.W, Schaaper, R.M, London, R.E, Pedersen, L.C.
登録日2006-09-15
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complex.
J.Biol.Chem., 281, 2006
2JW5
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BU of 2jw5 by Molmil
Polymerase Lambda BRCT domain
分子名称: DNA polymerase lambda
著者Mueller, G.A, Moon, A.F, DeRose, E.F, Pedersen, L.C, London, R.E.
登録日2007-10-05
公開日2007-10-23
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Polymerase Lambda BRCT domain
To be Published
2KHX
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BU of 2khx by Molmil
Drosha double-stranded RNA binding motif
分子名称: Ribonuclease 3
著者Mueller, G.A, Miller, M, Ghosh, M, DeRose, E.F, London, R.E, Hall, T.
登録日2009-04-13
公開日2010-02-23
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Solution structure of the Drosha double-stranded RNA-binding domain.
Silence, 1, 2010
6D7N
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BU of 6d7n by Molmil
Crystal structure of the W357R/W399R Importin alpha mutant
分子名称: 1,2-ETHANEDIOL, Peroxidase,Importin subunit alpha-1
著者Pedersen, L.C, London, R.E, Gabel, S.A.
登録日2018-04-25
公開日2019-03-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
6D7M
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BU of 6d7m by Molmil
Crystal structure of the W184R/W231R Importin alpha mutant
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Peroxidase,Importin subunit alpha-1, ...
著者Pedersen, L.C, London, R.E, Gabel, S.A.
登録日2018-04-25
公開日2019-03-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.187 Å)
主引用文献Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
4OUO
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BU of 4ouo by Molmil
anti-Bla g 1 scFv
分子名称: CHLORIDE ION, SULFATE ION, anti Bla g 1 scFv
著者Mueller, G.A, Ankney, J.A, Glesner, J, Khurana, T, Edwards, L.L, Pedersen, L.C, Perera, L, Slater, J.E, Pomes, A, London, R.E.
登録日2014-02-18
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Characterization of an anti-Bla g 1 scFv: Epitope mapping and cross-reactivity.
Mol.Immunol., 59, 2014
1ZM8
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BU of 1zm8 by Molmil
Apo Crystal structure of Nuclease A from Anabaena sp.
分子名称: MANGANESE (II) ION, Nuclease, SODIUM ION, ...
著者Ghosh, M, Meiss, G, Pingoud, A, London, R.E, Pedersen, L.C.
登録日2005-05-10
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into the Mechanism of Nuclease A, a beta beta alpha Metal Nuclease from Anabaena.
J.Biol.Chem., 280, 2005
2AE9
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BU of 2ae9 by Molmil
Solution Structure of the theta subunit of DNA polymerase III from E. coli
分子名称: DNA polymerase III, theta subunit
著者Mueller, G.A, Kirby, T.W, Derose, E.F, Li, D, Schaaper, R.M, London, R.E.
登録日2005-07-21
公開日2005-10-18
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Solution Structure of the Escherichia coli DNA Polymerase III {theta} Subunit.
J.Bacteriol., 187, 2005
3LQC
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BU of 3lqc by Molmil
X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain
分子名称: CARBONATE ION, DNA polymerase beta, DNA repair protein XRCC1, ...
著者Cuneo, M.J, Krahn, J.M, London, R.E.
登録日2010-02-09
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.349 Å)
主引用文献Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
Proc.Natl.Acad.Sci.USA, 107, 2010
3MQ1
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Crystal Structure of Dust Mite Allergen Der p 5
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Mite allergen Der p 5, ...
著者Mueller, G.A, Gosavi, R.A, Krahn, J.M, Edwards, L.L, Cuneo, M.J, Glesner, J, Pomes, A, Chapman, M.D, London, R.E, Pedersen, L.C.
登録日2010-04-27
公開日2010-06-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Der p 5 crystal structure provides insight into the group 5 dust mite allergens.
J.Biol.Chem., 285, 2010

 

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