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5DBC
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BU of 5dbc by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the dG base paired with a dG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DB7
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BU of 5db7 by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dT
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.209 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DBA
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BU of 5dba by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the dG base paired with a dT
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.965 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DB8
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BU of 5db8 by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dA
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DBB
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BU of 5dbb by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the dG base paired with a dA
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5DB9
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BU of 5db9 by Molmil
Structure of human DNA polymerase beta Host-Guest complex with the N7MG base paired with a dG
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*(FMG)P*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-08-21
Release date:2015-11-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA.
J.Am.Chem.Soc., 137, 2015
5EDW
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BU of 5edw by Molmil
Ternary structure of Dpo4 bound to G in the template base paired with incoming dTTP
Descriptor: CALCIUM ION, DNA (5'-D(*CP*TP*AP*AP*CP*GP*GP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2015-10-22
Release date:2016-11-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structure of Dpo4 DNA polymerase replicating across the genotoxic N7-methylguanine lesion
To Be Published
5EOZ
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BU of 5eoz by Molmil
Mutagenicity of 7-Benzyl guanine lesion and Replication by Human DNA Polymerase beta
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(GFL)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2015-11-10
Release date:2016-11-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.088 Å)
Cite:Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication.
Biochemistry, 2018
4J4K
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BU of 4j4k by Molmil
Crystal structure of glucose isomerase
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Xylose isomerase, ...
Authors:Kim, M.K, An, Y.J, Lee, S, Jeong, C.S, Cha, S.S.
Deposit date:2013-02-07
Release date:2014-04-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of glucose isomerase
To be Published
4JCH
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BU of 4jch by Molmil
OSH4 bound to an electrophilic oxysterol
Descriptor: (3beta,9beta,22R,25R)-3-hydroxyfurost-5-en-27-yl propanoate, Protein KES1
Authors:Koag, M.C, Kou, Y.I, Monzingo, A.F, Lee, S.
Deposit date:2013-02-21
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of OSH4 bound to an electrophilic oxysterol
To be Published
2N8V
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BU of 2n8v by Molmil
An NMR/SAXS structure of the PKI domain of the honeybee dicistrovirus, Israeli acute paralysis virus (IAPV) IRES
Descriptor: RNA (70-MER)
Authors:Au, H.H, Cornilescu, G, Mouzakis, K.D, Burke, J.E, Ren, Q, Lee, S, Butcher, S.E, Jan, E.
Deposit date:2015-10-27
Release date:2015-11-11
Last modified:2016-01-20
Method:SOLUTION NMR
Cite:Global shape mimicry of tRNA within a viral internal ribosome entry site mediates translational reading frame selection.
Proc.Natl.Acad.Sci.USA, 112, 2015
6CLY
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BU of 6cly by Molmil
Structure of human DNA polymerase beta complexed with 8-ClG as the template base in a 1-nucleotide gapped DNA
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2018-03-02
Release date:2019-03-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.186 Å)
Cite:Structure of human DNA polymerase beta complexed with 8-ClG as the template base in a 1-nucleotide gapped DNA
To Be Published
6CRH
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BU of 6crh by Molmil
Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2018-03-17
Release date:2019-03-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.327 Å)
Cite:Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion.
Molecules, 24, 2019
6CU9
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BU of 6cu9 by Molmil
Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable CTP and MANGANESE
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
Authors:Koag, M.-C, Lee, S.
Deposit date:2018-03-24
Release date:2019-03-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable CTP and MANGANESE
To Be Published
2F6M
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BU of 2f6m by Molmil
Structure of a Vps23-C:Vps28-N subcomplex
Descriptor: DECYLAMINE-N,N-DIMETHYL-N-OXIDE, MAGNESIUM ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ...
Authors:Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H.
Deposit date:2005-11-29
Release date:2006-04-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional organization of the ESCRT-I trafficking complex.
Cell(Cambridge,Mass.), 125, 2006
7FDA
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BU of 7fda by Molmil
CryoEM Structure of Reconstituted V-ATPase, state1
Descriptor: Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
Deposit date:2021-07-16
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
7FDB
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BU of 7fdb by Molmil
CryoEM Structures of Reconstituted V-ATPase,State2
Descriptor: Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
Deposit date:2021-07-16
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
7FDC
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BU of 7fdc by Molmil
CryoEM Structures of Reconstituted V-ATPase, state3
Descriptor: Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
Deposit date:2021-07-16
Release date:2021-12-22
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
7FDE
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BU of 7fde by Molmil
CryoEM Structures of Reconstituted V-ATPase, Oxr1 bound V1
Descriptor: Oxidation resistance protein 1, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
Deposit date:2021-07-16
Release date:2021-12-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
2F66
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BU of 2f66 by Molmil
Structure of the ESCRT-I endosomal trafficking complex
Descriptor: Protein SRN2, SULFATE ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ...
Authors:Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H.
Deposit date:2005-11-28
Release date:2006-04-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and functional organization of the ESCRT-I trafficking complex.
Cell(Cambridge,Mass.), 125, 2006
2K3M
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BU of 2k3m by Molmil
Rv1761c
Descriptor: Rv1761c, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Page, R.C, Moore, J.D, Lee, S, Opella, S.J, Cross, T.A.
Deposit date:2008-05-14
Release date:2009-01-06
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Backbone structure of a small helical integral membrane protein: A unique structural characterization.
Protein Sci., 18, 2009
6MXO
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BU of 6mxo by Molmil
Structure of HPoleta incorporating dCTP opposite the 3-prime Pt(DACH)-GG
Descriptor: (cyclohex-1-ene-1,2-diamine)platinum(2+), 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*CP*GP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ...
Authors:Ouzon-Shubeita, H, Lee, S.
Deposit date:2018-10-31
Release date:2019-02-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural basis for the bypass of the major oxaliplatin-DNA adducts by human DNA polymerase eta.
Biochem. J., 476, 2019
6MP3
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BU of 6mp3 by Molmil
Binary structure of DNA polymerase eta in complex with templating hypoxanthine
Descriptor: DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*IP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ...
Authors:Hawkins, M.A, Jung, H, Lee, S.
Deposit date:2018-10-05
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.907 Å)
Cite:Structural Analysis of Translesion Synthesis Across Hypoxanthine Lesion Using Human DNA Polymerase Eta
To Be Published
6MQ8
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BU of 6mq8 by Molmil
Binary structure of DNA polymerase eta in complex with templating hypoxanthine
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*IP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Hawkins, M.A, Jung, H, Lee, S.
Deposit date:2018-10-09
Release date:2019-10-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.969 Å)
Cite:Structural insights into the bypass of the major deaminated purines by translesion synthesis DNA polymerase.
Biochem.J., 2020
7LCD
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BU of 7lcd by Molmil
Crystal structure of human polymerase eta complexed with syn N7-acetophenoneguanine
Descriptor: DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(*CP*AP*T*(T0P)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA polymerase eta
Authors:Jung, H, Lee, S.
Deposit date:2021-01-10
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystal structure of human polymerase eta complexed with syn N7-acetophenoneguanine
To Be Published

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