7C2T
 
 | | Helical reconstruction of Zika virus complexed with Fab C10 | | Descriptor: | Heavy chain from Fab C10, Light chain from Fab C10, M protein, ... | | Authors: | Morrone, S, Chew, S.V, Lim, X.N, Ng, T.S, Kostyuchenko, V.A, Zhang, S, Lok, S.M. | | Deposit date: | 2020-05-09 | | Release date: | 2020-07-08 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (9.4 Å) | | Cite: | High flavivirus structural plasticity demonstrated by a non-spherical morphological variant.
Nat Commun, 11, 2020
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8HGA
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5DRB
 | | Crystal structure of WNK1 in complex with WNK463 | | Descriptor: | N-tert-butyl-1-(1-{5-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]pyridin-2-yl}piperidin-4-yl)-1H-imidazole-5-carboxamide, Serine/threonine-protein kinase WNK1 | | Authors: | Kohls, D, Xie, X. | | Deposit date: | 2015-09-15 | | Release date: | 2016-09-07 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Small-molecule WNK inhibition regulates cardiovascular and renal function.
Nat.Chem.Biol., 12, 2016
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8HNW
 | | Crystal structure of HpaCas9-sgRNA surveillance complex bound to double-stranded DNA | | Descriptor: | CRISPR-associated endonuclease Cas9, Non-target strand, Target strand, ... | | Authors: | Sun, W, Cheng, Z, Wang, Y. | | Deposit date: | 2022-12-08 | | Release date: | 2023-07-19 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8HNT
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3EUJ
 | | Crystal structure of MukE-MukF(residues 292-443)-MukB(head domain)-ATPgammaS complex, symmetric dimer | | Descriptor: | Chromosome partition protein mukB, Linker, Chromosome partition protein mukF, ... | | Authors: | Woo, J.S, Lim, J.H, Shin, H.C, Oh, B.H. | | Deposit date: | 2008-10-10 | | Release date: | 2009-01-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions.
Cell(Cambridge,Mass.), 136, 2009
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3EUK
 | | Crystal structure of MukE-MukF(residues 292-443)-MukB(head domain)-ATPgammaS complex, asymmetric dimer | | Descriptor: | Chromosome partition protein mukB, Linker, Chromosome partition protein mukE, ... | | Authors: | Woo, J.S, Lim, J.H, Shin, H.C, Oh, B.H. | | Deposit date: | 2008-10-10 | | Release date: | 2009-01-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions.
Cell(Cambridge,Mass.), 136, 2009
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3EUH
 | | Crystal Structure of the MukE-MukF Complex | | Descriptor: | Chromosome partition protein mukF, GLYCINE, MukE | | Authors: | Suh, M.K, Ku, B, Ha, N.C, Woo, J.S, Oh, B.H. | | Deposit date: | 2008-10-10 | | Release date: | 2009-01-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions.
Cell(Cambridge,Mass.), 136, 2009
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3R4Z
 | | Crystal structure of alpha-neoagarobiose hydrolase (ALPHA-NABH) in complex with alpha-d-galactopyranose from Saccharophagus degradans 2-40 | | Descriptor: | Glycosyl hydrolase family 32, N terminal, alpha-D-galactopyranose | | Authors: | Lee, S, Lee, J.Y, Ha, S.C, Shin, D.H, Kim, K.H, Bang, W.G, Kim, S.H, Choi, I.G. | | Deposit date: | 2011-03-18 | | Release date: | 2012-02-01 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of a key enzyme in the agarolytic pathway, alpha-neoagarobiose hydrolase from Saccharophagus degradans 2-40
Biochem.Biophys.Res.Commun., 412, 2011
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7SGR
 | | Structure of hemolysin A secretion system HlyB/D complex | | Descriptor: | Alpha-hemolysin translocation ATP-binding protein HlyB, Membrane fusion protein (MFP) family protein,Hemolysin secretion protein D, chromosomal, ... | | Authors: | Zhao, H, Chen, J. | | Deposit date: | 2021-10-07 | | Release date: | 2022-09-14 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | The hemolysin A secretion system is a multi-engine pump containing three ABC transporters.
Cell, 185, 2022
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7V5N
 | | Crystal structure of Fab fragment of bevacizumab bound to DNA aptamer | | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*GP*TP*TP*GP*GP*TP*GP*GP*TP*AP*GP*TP*TP*AP*CP*GP*TP*TP*CP*GP*C)-3'), IMIDAZOLE, ... | | Authors: | Hishiki, A, Tong, J, Todoroki, K, Hashimoto, H. | | Deposit date: | 2021-08-17 | | Release date: | 2022-02-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive detection.
Biosens.Bioelectron., 203, 2022
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2KAL
 | | NMR structure of fully methylated GATC site | | Descriptor: | 5'-D(*DCP*DGP*DCP*DAP*DGP*(6MA)P*DTP*DCP*DTP*DCP*DGP*DC)-3', 5'-D(*DGP*DCP*DGP*DAP*DGP*(6MA)P*DTP*DCP*DTP*DGP*DCP*DG)-3' | | Authors: | Bang, J, Bae, S, Park, C, Lee, J, Choi, B. | | Deposit date: | 2008-11-09 | | Release date: | 2009-02-10 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Structural and dynamics study of DNA dodecamer duplexes that contain un-, hemi-, or fully methylated GATC sites.
J.Am.Chem.Soc., 130, 2008
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7EP6
 | | Engineered Hepatitis B virus core antigen T=4 | | Descriptor: | Capsid protein,Immunoglobulin G-binding protein A | | Authors: | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | Deposit date: | 2021-04-26 | | Release date: | 2021-09-01 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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7EOY
 | | Engineered Hepatitis B virus core antigen T=3 | | Descriptor: | Capsid protein,Immunoglobulin G-binding protein A | | Authors: | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | Deposit date: | 2021-04-24 | | Release date: | 2021-09-01 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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7FDJ
 | | Engineered Hepatitis B virus core antigen with short linker T=4 | | Descriptor: | Capsid protein,Immunoglobulin G-binding protein A | | Authors: | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | Deposit date: | 2021-07-16 | | Release date: | 2021-09-01 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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5C27
 | | Crystal structure of SYK in complex with compound 2 | | Descriptor: | 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}-N-[4-(methylcarbamoyl)phenyl]benzamide, GLU-VAL-TYR-GLU-SER, GLYCEROL, ... | | Authors: | Han, S, Chang, J. | | Deposit date: | 2015-06-15 | | Release date: | 2015-10-07 | | Last modified: | 2016-02-03 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free-Energy Perturbation (FEP).
Chemmedchem, 11, 2016
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5C26
 | | Crystal structure of SYK in complex with compound 1 | | Descriptor: | 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzamide, GLU-VAL-PTR-GLU-SER-PRO, Tyrosine-protein kinase SYK | | Authors: | Han, S, Chang, J. | | Deposit date: | 2015-06-15 | | Release date: | 2015-10-07 | | Last modified: | 2016-02-03 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free-Energy Perturbation (FEP).
Chemmedchem, 11, 2016
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7CRG
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8HIA
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4FK3
 | | B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203 | | Descriptor: | N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide, Serine/threonine-protein kinase B-raf | | Authors: | Zhang, Y, Wang, W, Zhang, K.Y.J. | | Deposit date: | 2012-06-12 | | Release date: | 2012-08-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.
Proc.Natl.Acad.Sci.USA, 105, 2008
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5IBU
 | | 6652 Fab (unbound) | | Descriptor: | 6652 Heavy Chain, 6652 Light Chain | | Authors: | Raymond, D.D, Harrison, S.C. | | Deposit date: | 2016-02-22 | | Release date: | 2016-11-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
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5IBT
 | | UCA Fab (unbound) from 6515 Lineage | | Descriptor: | GLYCEROL, UCA Heavy Chain, UCA Light Chain | | Authors: | Raymond, D.D, Harrison, S.C. | | Deposit date: | 2016-02-22 | | Release date: | 2016-11-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Nat. Med., 22, 2016
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5IBL
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5IJT
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6JPV
 | | Structural analysis of AIMP2-DX2 and HSP70 interaction | | Descriptor: | Heat shock 70 kDa protein 1A,Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 | | Authors: | Cho, H.Y, Son, S.Y, Jeon, Y.H. | | Deposit date: | 2019-03-28 | | Release date: | 2019-10-02 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.15000653 Å) | | Cite: | Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.
Nat.Chem.Biol., 16, 2020
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