8SHC
 
 | | Pendrin in complex with Niflumic acid | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, CHLORIDE ION, ... | | 著者 | Wang, L, Hoang, A, Zhou, M. | | 登録日 | 2023-04-13 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of anion exchange and small-molecule inhibition of pendrin.
Nat Commun, 15, 2024
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8SGW
 | | Pendrin in complex with chloride | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, CHOLESTEROL, ... | | 著者 | Wang, L, Hoang, A, Zhou, M. | | 登録日 | 2023-04-13 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Mechanism of anion exchange and small-molecule inhibition of pendrin.
Nat Commun, 15, 2024
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6O8C
 | | Crystal structure of STING CTT in complex with TBK1 | | 分子名称: | N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein | | 著者 | Li, P, Zhao, B, Du, F. | | 登録日 | 2019-03-09 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
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6O8B
 | | Crystal structure of STING CTD in complex with TBK1 | | 分子名称: | N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein | | 著者 | Li, P, Zhao, B, Du, F. | | 登録日 | 2019-03-09 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
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6VP0
 | | Human Diacylglycerol Acyltransferase 1 in complex with oleoyl-CoA | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Diacylglycerol O-acyltransferase 1, Lauryl Maltose Neopentyl Glycol, ... | | 著者 | Wang, L, Qian, H, Han, Y, Nian, Y, Ren, Z, Zhang, H, Hu, L, Prasad, B.V.V, Yan, N, Zhou, M. | | 登録日 | 2020-02-01 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure and mechanism of human diacylglycerol O-acyltransferase 1.
Nature, 581, 2020
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6VYH
 | | Cryo-EM structure of SLC40/ferroportin in complex with Fab | | 分子名称: | 11F9 heavy-chain, 11F9 light-chain, COBALT (II) ION, ... | | 著者 | Shen, J, Ren, Z, Pan, Y, Gao, S, Yan, N, Zhou, M. | | 登録日 | 2020-02-26 | | 公開日 | 2020-11-11 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of ion transport and inhibition in ferroportin.
Nat Commun, 11, 2020
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6WIK
 | | Cryo-EM structure of SLC40/ferroportin with Fab in the presence of hepcidin | | 分子名称: | 11F9 Fab heavy-chain, 11F9 Fab light-chain, Solute carrier family 40 protein | | 著者 | Shen, J, Ren, Z, Pan, Y, Gao, S, Yan, N, Zhou, M. | | 登録日 | 2020-04-10 | | 公開日 | 2020-11-11 | | 最終更新日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of ion transport and inhibition in ferroportin.
Nat Commun, 11, 2020
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6WSI
 | | Intact cis-2,3-epoxysuccinic acid bound to Isocitrate Lyase-1 from Mycobacterium tuberculosis | | 分子名称: | (2R,3S)-oxirane-2,3-dicarboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Krieger, I.V, Mellott, D, Meek, T.D, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2020-05-01 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | Covalent Inactivation of Mycobacterium tuberculosis Isocitrate Lyase by cis -2,3-Epoxy-Succinic Acid.
Acs Chem.Biol., 16, 2021
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4QCC
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7RB1
 | | Isocitrate Lyase-1 from Mycobacterium tuberculosis covalently modified by 5-descarboxy-5-nitro-D-isocitric acid | | 分子名称: | (3E)-3-(hydroxyimino)propanoic acid, GLYCEROL, GLYOXYLIC ACID, ... | | 著者 | Krieger, I.V, Mellott, D, Meek, T, Sacchettini, J.C. | | 登録日 | 2021-07-05 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanism-Based Inactivation of Mycobacterium tuberculosis Isocitrate Lyase 1 by (2 R ,3 S )-2-Hydroxy-3-(nitromethyl)succinic acid.
J.Am.Chem.Soc., 143, 2021
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3PZZ
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3OW9
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3OVJ
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3OVL
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3Q2X
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