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3SIJ
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BU of 3sij by Molmil
The X-ray crystal structure of poly(ADP-ribose) glycohydrolase E115A mutant from Thermomonospora curvata
Descriptor: poly(ADP-ribose) glycohydrolase
Authors:Dunstan, M.S, Leys, D.
Deposit date:2011-06-18
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
Nature, 477, 2011
4L2H
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BU of 4l2h by Molmil
Structure of a catalytically inactive PARG in complex with a poly-ADP-ribose fragment
Descriptor: Poly(ADP-ribose) glycohydrolase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Brassington, A, Dunstan, M.S, Leys, D.
Deposit date:2013-06-04
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Visualization of poly(ADP-ribose) bound to PARG reveals inherent balance between exo- and endo-glycohydrolase activities.
Nat Commun, 4, 2013
5LTE
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BU of 5lte by Molmil
Crystal structure of the alpha subunit of heme dependent oxidative N-demethylase (HODM)
Descriptor: 2-ETHOXYETHANOL, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ...
Authors:Ortmayer, M, Leys, D.
Deposit date:2016-09-06
Release date:2016-11-09
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.
Nature, 539, 2016
5LTI
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BU of 5lti by Molmil
Crystal structure of the alpha subunit of heme dependent oxidative N-demethylase (HODM) in complex with the dimethylamine substrate
Descriptor: DI(HYDROXYETHYL)ETHER, DIMETHYLAMINE, NITRIC OXIDE, ...
Authors:Ortmayer, M, Leys, D.
Deposit date:2016-09-06
Release date:2016-11-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.
Nature, 539, 2016
5LTH
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BU of 5lth by Molmil
Crystal structure of the alpha subunit of heme dependent oxidative N-demethylase (HODM) in complex with the dimethylamine substrate
Descriptor: DI(HYDROXYETHYL)ETHER, DIMETHYLAMINE, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Ortmayer, M, Leys, D.
Deposit date:2016-09-06
Release date:2016-11-09
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme.
Nature, 539, 2016
3IVY
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BU of 3ivy by Molmil
Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125, p212121 crystal form
Descriptor: Cytochrome P450 CYP125, PROTOPORPHYRIN IX CONTAINING FE
Authors:McLean, K.J, Levy, C, Munro, A.W, Leys, D.
Deposit date:2009-09-02
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.352 Å)
Cite:The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection.
J.Biol.Chem., 284, 2009
3IW2
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BU of 3iw2 by Molmil
Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with econazole
Descriptor: 4-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Cytochrome P450 CYP125, PROTOPORPHYRIN IX CONTAINING FE
Authors:McLean, K.J, Levy, C, Munro, A.W, Leys, D.
Deposit date:2009-09-02
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection.
J.Biol.Chem., 284, 2009
3IW0
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BU of 3iw0 by Molmil
Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125, C2221 crystal form
Descriptor: Cytochrome P450 CYP125, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:McLean, K.J, Levy, C, Munro, A.W, Leys, D.
Deposit date:2009-09-02
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection.
J.Biol.Chem., 284, 2009
3IW1
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BU of 3iw1 by Molmil
Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with androstenedione
Descriptor: 4-ANDROSTENE-3-17-DIONE, Cytochrome P450 CYP125, PROTOPORPHYRIN IX CONTAINING FE
Authors:McLean, K.J, Levy, C, Munro, A.W, Leys, D.
Deposit date:2009-09-02
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection.
J.Biol.Chem., 284, 2009
4EPQ
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BU of 4epq by Molmil
canonical poly(ADP-ribose) glycohydrolase RBPI inhibitor complex from Tetrahymena thermophila
Descriptor: 3-{(5Z)-5-[5-chloro-1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}propanoic acid, Poly(ADP-ribose) glycohydrolase
Authors:Dunstan, M.S, Leys, D.
Deposit date:2012-04-17
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase.
Nat Commun, 3, 2012
4EPP
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BU of 4epp by Molmil
Canonical poly(ADP-ribose) glycohydrolase from Tetrahymena thermophila.
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Poly(ADP-ribose) glycohydrolase
Authors:Dunstan, M.S, Leys, D.
Deposit date:2012-04-17
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase.
Nat Commun, 3, 2012
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