3IVY

Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125, p212121 crystal form

Summary for 3IVY

Entry DOI	10.2210/pdb3ivy/pdb
Related	3IW0 3IW1 3IW2
Descriptor	Cytochrome P450 CYP125, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	cholesterol, cytochrome p450, tuberculosis, monooxygenase, heme, iron, metal-binding, oxidoreductase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	49107.98
Authors	McLean, K.J.,Levy, C.,Munro, A.W.,Leys, D. (deposition date: 2009-09-02, release date: 2009-11-03, Last modification date: 2023-09-06)
Primary citation	McLean, K.J.,Lafite, P.,Levy, C.,Cheesman, M.R.,Mast, N.,Pikuleva, I.A.,Leys, D.,Munro, A.W. The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection. J.Biol.Chem., 284:35524-35533, 2009 Cited by PubMed: 19846552 DOI: 10.1074/jbc.M109.032706 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.352 Å)

Structure validation