9ICJ
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9ICE
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9ICI
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9ICB
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5EVO
| Structure of Dehydroascrobate Reductase from Pennisetum Americanum in complex with two non-native ligands, Acetate in the G-site and Glycerol in the H-site | 分子名称: | ACETATE ION, Dehydroascorbate reductase, GLYCEROL | 著者 | Kumar, A.O, Das, B.K, Arockiasamy, A. | 登録日 | 2015-11-20 | 公開日 | 2016-05-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Non-native ligands define the active site of Pennisetum glaucum (L.) R. Br dehydroascorbate reductase. Biochem.Biophys.Res.Commun., 473, 2016
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5MU1
| UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum soaked with K2PtI6 | 分子名称: | CALCIUM ION, IODIDE ION, PLATINUM (II) ION, ... | 著者 | Roversi, P, Caputo, A.T, Hill, J, Alonzi, D.S, Zitzmann, N. | 登録日 | 2017-01-11 | 公開日 | 2017-07-26 | 最終更新日 | 2023-03-08 | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | 主引用文献 | Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MZO
| UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (open conformation) | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Roversi, P, Caputo, A.T, Hill, J, Alonzi, D.S, Zitzmann, N. | 登録日 | 2017-02-01 | 公開日 | 2017-07-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | 主引用文献 | Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5N2J
| UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (closed form) | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Roversi, P, Caputo, A.T, Hill, J, Alonzi, D.S, Zitzmann, N. | 登録日 | 2017-02-07 | 公開日 | 2017-07-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NV4
| UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum double mutant D611C:G1050C | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FORMIC ACID, UDP-glucose-glycoprotein glucosyltransferase-like protein, ... | 著者 | Roversi, P, Caputo, A.T, Hill, J, Alonzi, D.S, Zitzmann, N. | 登録日 | 2017-05-03 | 公開日 | 2017-07-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8IVX
| Crystal structure of NRP2 in complex with aNRP2-14 Fab fragment | 分子名称: | 1,2-ETHANEDIOL, Heavy chain of antibody 14V4 Fab fragment, Light chain of antibody 14V4 Fab fragment, ... | 著者 | Geng, Y, Zhai, L. | 登録日 | 2023-03-29 | 公開日 | 2023-07-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer. Sci Transl Med, 15, 2023
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8IVW
| Crystal structure of NRP2 in complex with aNRP2-10 Fab fragment | 分子名称: | Heavy chian of antibody 10V8 Fab fragment, Light chain of antibody 10V8 Fab fragment, Neuropilin-2 | 著者 | Geng, Y, Zhai, L. | 登録日 | 2023-03-29 | 公開日 | 2023-07-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.205 Å) | 主引用文献 | Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer. Sci Transl Med, 15, 2023
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7BWE
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7BWO
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7DK1
| Crystal structure of Zinc bound SARS-CoV-2 main protease | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3C-like proteinase, CHLORIDE ION, ... | 著者 | Sonkar, K.S, Panchariya, L, Kuila, S, Khan, W.A, Arockiasamy, A. | 登録日 | 2020-11-22 | 公開日 | 2021-06-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | 主引用文献 | Zinc 2+ ion inhibits SARS-CoV-2 main protease and viral replication in vitro. Chem.Commun.(Camb.), 57, 2021
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5F9O
| Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235.09 in complex with HIV-1 clade A/E 93TH057 gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CH235.09 Light chain, ... | 著者 | Joyce, M.G, Mascola, J.R, Kwong, P.D. | 登録日 | 2015-12-10 | 公開日 | 2016-03-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody. Cell, 165, 2016
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5F9W
| Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235 in complex with HIV-1 clade A/E 93TH057 gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of CH235-lineage antibody CH235, Light chain of CH235-lineage antibody CH235, ... | 著者 | Chen, L, Zhou, T, Kwong, P.D. | 登録日 | 2015-12-10 | 公開日 | 2016-03-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.8911 Å) | 主引用文献 | Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody. Cell, 165, 2016
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5F96
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2MI1
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6HTN
| Structure of a fucose lectin from Kordia zhangzhouensis in complex with methyl-fucoside | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | 著者 | Varrot, A. | 登録日 | 2018-10-04 | 公開日 | 2019-01-23 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Architecture and Evolution of Blade Assembly in beta-propeller Lectins. Structure, 27, 2019
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6TS8
| Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) double cysteine mutant G177C/A786C. | 分子名称: | UDP-glucose-glycoprotein glucosyltransferase-like protein | 著者 | Roversi, P, Zitzmann, N, Ibba, R, Hensen, M, Chandran, A. | 登録日 | 2019-12-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (4.6 Å) | 主引用文献 | Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase. Structure, 29, 2021
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6TRT
| Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) double cysteine mutant S180C/T742C. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TERBIUM(III) ION, UDP-glucose-glycoprotein glucosyltransferase-like protein, ... | 著者 | Roversi, P, Zitzmann, N, Ibba, R, Hensen, M. | 登録日 | 2019-12-19 | 公開日 | 2020-01-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (4.58 Å) | 主引用文献 | Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase. Structure, 29, 2021
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6TRF
| Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) purified from cells treated with kifunensine. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, UDP-glucose-glycoprotein glucosyltransferase-like protein, ... | 著者 | Roversi, P, Zitzmann, N. | 登録日 | 2019-12-18 | 公開日 | 2020-01-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (4.106 Å) | 主引用文献 | Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase. Structure, 29, 2021
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6TS2
| Truncated version of Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) lacking domain TRXL2 (417-650). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, UDP-glucose-glycoprotein glucosyltransferase-like protein,UDP-glucose-glycoprotein glucosyltransferase-like protein, ... | 著者 | Roversi, P, Zitzmann, N. | 登録日 | 2019-12-19 | 公開日 | 2020-01-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (5.74 Å) | 主引用文献 | Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase. Structure, 29, 2021
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3K5J
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3KK7
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