6TRT

Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) double cysteine mutant S180C/T742C.

Summary for 6TRT

• Entry DOI: 10.2210/pdb6trt/pdb
• Related: 3WZS 3WZT 5MU1 5MZO 5N2J 5NV4 6FSN 6TRF
• Descriptor: UDP-glucose-glycoprotein glucosyltransferase-like protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: endoplasmic reticulum, glycoprotein folding, erqc, uggt, terbium, protein binding
• Biological source: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
• Total number of polymer chains: 1
• Total formula weight: 173145.96

Authors

Roversi, P.,Zitzmann, N.,Ibba, R.,Hensen, M. (deposition date: 2019-12-19, release date: 2020-01-08, Last modification date: 2024-01-24)

• Primary citation: Modenutti, C.P.,Blanco Capurro, J.I.,Ibba, R.,Alonzi, D.S.,Song, M.N.,Vasiljevic, S.,Kumar, A.,Chandran, A.V.,Tax, G.,Marti, L.,Hill, J.C.,Lia, A.,Hensen, M.,Waksman, T.,Rushton, J.,Rubichi, S.,Santino, A.,Marti, M.A.,Zitzmann, N.,Roversi, P.; Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase.; Structure, 29:357-, 2021; PubMed: 33352114; DOI: 10.1016/j.str.2020.11.017

Experimental method

X-RAY DIFFRACTION (4.58 Å)