6FSN

Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 1)

Summary for 6FSN

Entry DOI	10.2210/pdb6fsn/pdb
Related	5MU1 5MZO 5N2J 5NV4
Descriptor	UDP-glucose-glycoprotein glucosyltransferase-like protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total)
Functional Keywords	glycoprotein, misfolding, transferase, endoplasmic reticulum. udp-glucose, gt24
Biological source	Chaetomium thermophilum
Total number of polymer chains	1
Total formula weight	36527.20
Authors	Roversi, P.,Le Cornu, J.D.,Hill, J.,Alonzi, D.S.,Zitzmann, N. (deposition date: 2018-02-19, release date: 2019-03-20, Last modification date: 2024-10-16)
Primary citation	Caputo, A.T.,Ibba, R.,Le Cornu, J.D.,Darlot, B.,Hensen, M.,Lipp, C.B.,Marciano, G.,Vasiljevic, S.,Zitzmann, N.,Roversi, P. Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint. Front Mol Biosci, 2022 Cited by DOI: 10.3389/fmolb.2022.960248 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.19 Å)

Structure validation