7DK1

Crystal structure of Zinc bound SARS-CoV-2 main protease

Summary for 7DK1

Entry DOI	10.2210/pdb7dk1/pdb
Descriptor	3C-like proteinase, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total)
Functional Keywords	sars-cov-2, main protease, zinc, mpro-zinc complex, peptide binding protein, hydrolase
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains	2
Total formula weight	68476.55
Authors	Sonkar, K.S.,Panchariya, L.,Kuila, S.,Khan, W.A.,Arockiasamy, A. (deposition date: 2020-11-22, release date: 2021-06-30, Last modification date: 2023-11-29)
Primary citation	Panchariya, L.,Khan, W.A.,Kuila, S.,Sonkar, K.,Sahoo, S.,Ghoshal, A.,Kumar, A.,Verma, D.K.,Hasan, A.,Khan, M.A.,Jain, N.,Mohapatra, A.K.,Das, S.,Thakur, J.K.,Maiti, S.,Nanda, R.K.,Halder, R.,Sunil, S.,Arockiasamy, A. Zinc 2+ ion inhibits SARS-CoV-2 main protease and viral replication in vitro. Chem.Commun.(Camb.), 57:10083-10086, 2021 Cited by PubMed: 34514483 DOI: 10.1039/d1cc03563k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.902 Å)

Structure validation