7C0M
| Human cGAS-nucleosome complex | 分子名称: | Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1-B/E, ... | 著者 | Kujirai, T, Zierhut, C, Takizawa, Y, Kim, R, Negishi, L, Uruma, N, Hirai, S, Funabiki, H, Kurumizaka, H. | 登録日 | 2020-05-01 | 公開日 | 2020-09-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis for the inhibition of cGAS by nucleosomes. Science, 370, 2020
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5AY8
| Crystal structure of human nucleosome containing H3.Y | 分子名称: | CHLORIDE ION, DNA (146-MER), H3.Y, ... | 著者 | Kujirai, T, Horikoshi, N, Sato, K, Maehara, K, Machida, S, Osakabe, A, Kimura, H, Ohkawa, Y, Kurumizaka, H. | 登録日 | 2015-08-10 | 公開日 | 2016-04-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure and function of human histone H3.Y nucleosome Nucleic Acids Res., 44, 2016
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6A5L
| RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA | 分子名称: | DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-24 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5R
| RNA polymerase II elongation complex stalled at SHL(-2) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-25 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5T
| RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-25 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5U
| RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation | 分子名称: | DNA (198-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-25 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5P
| RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-25 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5O
| RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-06-25 | 公開日 | 2018-10-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (9.9 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6INQ
| RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA (+1 position) | 分子名称: | DNA (198-MER), DNA (31-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | 登録日 | 2018-10-26 | 公開日 | 2019-04-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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5B3N
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8JL9
| Cryo-EM structure of the human nucleosome with scFv | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-06-02 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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8JLD
| Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-06-02 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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8JLB
| Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-06-02 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.36 Å) | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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8JLA
| Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4 | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-06-02 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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8JH2
| RNA polymerase II elongation complex bound with Elf1, Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome | 分子名称: | DNA (218-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H. | 登録日 | 2023-05-22 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | 主引用文献 | Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA. J.Biol.Chem., 299, 2023
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8JH4
| RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H. | 登録日 | 2023-05-22 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA. J.Biol.Chem., 299, 2023
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8JH3
| RNA polymerase II elongation complex containing 40 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H. | 登録日 | 2023-05-22 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA. J.Biol.Chem., 299, 2023
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7DBH
| The mouse nucleosome structure containing H3mm18 | 分子名称: | DNA (126-MER), Histone H2A type 1-B, Histone H2B type 3-A, ... | 著者 | Hirai, S, Takizawa, Y, Kujirai, T, Kurumizaka, H. | 登録日 | 2020-10-20 | 公開日 | 2022-01-19 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant. Nucleic Acids Res., 50, 2022
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6KXV
| Crystal structure of a nucleosome containing Leishmania histone H3 | 分子名称: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Dacher, M, Taguchi, H, Kujirai, T, Kurumizaka, H. | 登録日 | 2019-09-13 | 公開日 | 2020-07-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.63 Å) | 主引用文献 | Incorporation and influence of Leishmania histone H3 in chromatin. Nucleic Acids Res., 47, 2019
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6KVD
| Crystal structure of human nucleosome containing H2A.J | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A.J, ... | 著者 | Tanaka, H, Koyama, M, Sato, S, Kujirai, T, Kurumizaka, H. | 登録日 | 2019-09-04 | 公開日 | 2019-12-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Biochemical and structural analyses of the nucleosome containing human histone H2A.J. J.Biochem., 167, 2020
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8KB5
| Cryo-EM structure of the human nucleosome containing H3.8 | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Hirai, H, Kujirai, T, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-08-03 | 公開日 | 2023-10-18 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.26133 Å) | 主引用文献 | Cryo-EM and biochemical analyses of the nucleosome containing the human histone H3 variant H3.8. J.Biochem., 174, 2023
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8HE5
| RNA polymerase II elongation complex bound with Rad26 and Elf1, stalled at SHL(-3.5) of the nucleosome | 分子名称: | DNA (198-MER), DNA repair protein, DNA-directed RNA polymerase subunit, ... | 著者 | Osumi, K, Kujirai, T, Ehara, H, Kinoshita, C, Saotome, M, Kagawa, W, Sekine, S, Takizawa, Y, Kurumizaka, H. | 登録日 | 2022-11-07 | 公開日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (6.95 Å) | 主引用文献 | Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
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7VBM
| The mouse nucleosome structure containing H3mm18 aided by PL2-6 scFv | 分子名称: | DNA (126-MER), Histone H2A type 1-B, Histone H2B type 3-A, ... | 著者 | Hirai, S, Takizawa, Y, Kujirai, T, Kurumizaka, H. | 登録日 | 2021-08-31 | 公開日 | 2022-01-19 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant. Nucleic Acids Res., 50, 2022
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6IR9
| RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | 登録日 | 2018-11-12 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors. Science, 363, 2019
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6J50
| RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome (tilted conformation) | 分子名称: | DNA (198-MER), DNA (41-MER), DNA-directed RNA polymerase subunit, ... | 著者 | Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. | 登録日 | 2019-01-10 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structural insight into nucleosome transcription by RNA polymerase II with elongation factors. Science, 363, 2019
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