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3IYA
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BU of 3iya by Molmil
Association of the pr peptides with dengue virus blocks membrane fusion at acidic pH
Descriptor: Envelope protein, prM protein
Authors:Yu, I, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Rossmann, M.G, Chen, J.
Deposit date:2009-06-01
Release date:2010-04-14
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (22 Å)
Cite:Association of the pr peptides with dengue virus at acidic pH blocks membrane fusion.
J.Virol., 83, 2009
1DGI
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BU of 1dgi by Molmil
Cryo-EM structure of human poliovirus(serotype 1)complexed with three domain CD155
Descriptor: POLIOVIRUS RECEPTOR, VP1, VP2, ...
Authors:He, Y, Bowman, V.D, Mueller, S, Bator, C.M, Bella, J, Peng, X, Baker, T.S, Wimmer, E, Kuhn, R.J, Rossmann, M.G.
Deposit date:1999-11-24
Release date:2000-01-24
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (22 Å)
Cite:Interaction of the poliovirus receptor with poliovirus.
Proc.Natl.Acad.Sci.USA, 97, 2000
6W2U
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BU of 6w2u by Molmil
Mayaro Virus glycoprotein E1 ectodomain and glycoportien E2 ectodomain asymmetric unit
Descriptor: Spike glycoprotein E1, Spike glycoprotein E2
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-03-08
Release date:2020-10-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6W09
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BU of 6w09 by Molmil
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Descriptor: E1 glycoprotein, E2 glycoprotein, E3, ...
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-02-29
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6W1C
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BU of 6w1c by Molmil
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Descriptor: E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ...
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-03-04
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6VYV
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BU of 6vyv by Molmil
Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Descriptor: E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ...
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2020-02-27
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.33 Å)
Cite:Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6WDT
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BU of 6wdt by Molmil
Enterovirus D68 in complex with human monoclonal antibody EV68-228
Descriptor: EV68-228 heavy chain, EV68-228 light chain, viral protein 1, ...
Authors:Fu, J, Vogt, M.R, Klose, T, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-04-01
Release date:2020-07-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
6WDS
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BU of 6wds by Molmil
Enterovirus D68 in complex with human monoclonal antibody EV68-159
Descriptor: EV68-159 heavy chain, EV68-159 light chain, viral protein 1, ...
Authors:Fu, J, Klose, T, Vogt, M.R, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-04-01
Release date:2020-07-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
1THD
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BU of 1thd by Molmil
COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION
Descriptor: Major envelope protein E
Authors:Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2004-06-01
Release date:2004-09-28
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Conformational changes of the flavivirus e glycoprotein
Structure, 12, 2004
1WYK
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BU of 1wyk by Molmil
SINDBIS VIRUS CAPSID PROTEIN (114-264)
Descriptor: 1,4-DIETHYLENE DIOXIDE, FORMYL GROUP, SINDBIS VIRUS CAPSID PROTEIN
Authors:Lee, S, Kuhn, R.J, Rossmann, M.G.
Deposit date:1998-01-12
Release date:1998-04-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Probing the potential glycoprotein binding site of sindbis virus capsid protein with dioxane and model building.
Proteins, 33, 1998
3J0F
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BU of 3j0f by Molmil
Sindbis virion
Descriptor: Capsid protein, E1 envelope glycoprotein, E2 envelope glycoprotein
Authors:Tang, J, Jose, J, Zhang, W, Chipman, P, Kuhn, R.J, Baker, T.S.
Deposit date:2011-07-08
Release date:2011-10-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Molecular Links between the E2 Envelope Glycoprotein and Nucleocapsid Core in Sindbis Virus.
J.Mol.Biol., 414, 2011
3IXY
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BU of 3ixy by Molmil
The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
Descriptor: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ...
Authors:Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H.
Deposit date:2009-02-26
Release date:2009-10-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody
Embo J., 28, 2009
3IXX
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BU of 3ixx by Molmil
The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53
Descriptor: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ...
Authors:Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H.
Deposit date:2009-02-26
Release date:2009-10-27
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody
Embo J., 28, 2009
3J0B
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BU of 3j0b by Molmil
cryo-EM reconstruction of West Nile virus
Descriptor: envelope glycoprotein E
Authors:Zhang, W, Kaufmann, B, Chipman, P.R, Kuhn, R.J, Rossmann, M.G.
Deposit date:2011-06-15
Release date:2012-12-19
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (10.3 Å)
Cite:Membrane curvature in flaviviruses.
J.Struct.Biol., 183, 2013
3J8D
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BU of 3j8d by Molmil
Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5
Descriptor: Envelope protein E, antibody E111 Fab fragment, glycoprotein DIII
Authors:Zhang, X.Z, Sheng, J, Austin, S.K, Hoornweg, T, Smit, J.M, Kuhn, R.J, Diamond, M.S, Rossmann, M.G.
Deposit date:2014-10-13
Release date:2014-11-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (26 Å)
Cite:Structure of Acidic pH Dengue Virus Showing the Fusogenic Glycoprotein Trimers.
J.Virol., 89, 2015
3J35
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BU of 3j35 by Molmil
Cryo-EM reconstruction of Dengue virus at 37 C
Descriptor: envelope protein
Authors:Zhang, X.Z, Sheng, J, Plevka, P, Kuhn, R.J, Diamond, M.S, Rossmann, M.G.
Deposit date:2013-02-24
Release date:2013-04-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Dengue structure differs at the temperatures of its human and mosquito hosts.
Proc.Natl.Acad.Sci.USA, 110, 2013
2OF6
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BU of 2of6 by Molmil
Structure of immature West Nile virus
Descriptor: envelope glycoprotein E
Authors:Zhang, Y, Kaufmann, B, Chipman, P.R, Kuhn, R.J, Rossmann, M.G.
Deposit date:2007-01-02
Release date:2007-04-03
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (24 Å)
Cite:Structure of immature west nile virus.
J.Virol., 81, 2007
2R29
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BU of 2r29 by Molmil
Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography
Descriptor: Envelope protein E, Heavy chain of Fab 1A1D-2, Light chain of Fab 1A1D-2
Authors:Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2007-08-24
Release date:2007-12-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
2R69
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BU of 2r69 by Molmil
Crystal structure of Fab 1A1D-2 complexed with E-DIII of Dengue virus at 3.8 angstrom resolution
Descriptor: Heavy chain of 1A1D-2, Light chain of 1A1D-2, Major envelope protein E
Authors:Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
Deposit date:2007-09-05
Release date:2007-12-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
2R6P
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BU of 2r6p by Molmil
Fit of E protein and Fab 1A1D-2 into 24 angstrom resolution cryoEM map of Fab complexed with dengue 2 virus.
Descriptor: Heavy chain of 1A1D-2, Light chain of 1A1D-2, Major envelope protein E
Authors:Lok, S.M, Kostyuchenko, V.K, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Rossmann, M.G.
Deposit date:2007-09-06
Release date:2007-12-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (24 Å)
Cite:Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
3ZFF
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BU of 3zff by Molmil
Human enterovirus 71 in complex with capsid binding inhibitor WIN51711
Descriptor: 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, VP1, VP2, ...
Authors:Plevka, P, Perera, R, Yap, M.L, Cardosa, J, Kuhn, R.J, Rossmann, M.G.
Deposit date:2012-12-11
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of Human Enterovirus 71 in Complex with a Capsid-Binding Inhibitor.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZFG
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BU of 3zfg by Molmil
Human enterovirus 71 in complex with capsid binding inhibitor WIN51711
Descriptor: 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, VP1, VP2, ...
Authors:Plevka, P, Perera, R, Yap, M.L, Cardosa, J, Kuhn, R.J, Rossmann, M.G.
Deposit date:2012-12-11
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Human Enterovirus 71 in Complex with a Capsid-Binding Inhibitor.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZFE
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BU of 3zfe by Molmil
Human enterovirus 71 in complex with capsid binding inhibitor WIN51711
Descriptor: CHLORIDE ION, SODIUM ION, SPHINGOSINE, ...
Authors:Plevka, P, Perera, R, Yap, M.L, Cardosa, J, Kuhn, R.J, Rossmann, M.G.
Deposit date:2012-12-11
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Human Enterovirus 71 in Complex with a Capsid-Binding Inhibitor.
Proc.Natl.Acad.Sci.USA, 110, 2013
4AED
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BU of 4aed by Molmil
Crystal structure of Human enterovirus 71
Descriptor: CALCIUM ION, LAURIC ACID, VP1, ...
Authors:Plevka, P, Perera, R, Kuhn, R.J, Rossmann, M.G.
Deposit date:2012-01-09
Release date:2012-04-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal Structure of Human Enterovirus 71.
Science, 336, 2012
4C0Y
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BU of 4c0y by Molmil
Cryo-EM reconstruction of empty enterovirus 71 in complex with a neutralizing antibody E18
Descriptor: FAB EV18 4 D6-1 F1 G9, VP1, VP2, ...
Authors:Plevka, P, Perera, R, Cardosa, J, Suksatu, A, Kuhn, R.J, Rossmann, M.G.
Deposit date:2013-08-08
Release date:2014-02-05
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Neutralizing Antibodies Can Initiate Genome Release from Human Enterovirus 71.
Proc.Natl.Acad.Sci.USA, 111, 2014

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