6XSD
 
 | | Patient-derived B2GPI | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1 | | Authors: | Klenotic, P.A, Yu, E.W.Y. | | Deposit date: | 2020-07-15 | | Release date: | 2021-07-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | B2-Glycoprotein I and it's role in APS
To Be Published
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6XST
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7JIK
 | | Human recombinant Beta-2-Glycoprotein 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1, ... | | Authors: | Klenotic, P.A, Yu, E.W.Y. | | Deposit date: | 2020-07-23 | | Release date: | 2021-07-28 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Beta-2-Glycoprotein I and it's role in APS
To Be Published
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7KG4
 | | Recombinant Beta-2-Glycoprotein I antibody recognition loop mutant | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Klenotic, P.A, Yu, E.W. | | Deposit date: | 2020-10-15 | | Release date: | 2021-10-20 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Beta-2-Glycoprotein I and its role in APS
To be published
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3R6B
 | | Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3 | | Descriptor: | 1,2-ETHANEDIOL, Thrombospondin-1 | | Authors: | Page, R.C, Klenotic, P.A, Misra, S, Silverstein, R.L. | | Deposit date: | 2011-03-21 | | Release date: | 2011-08-10 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.
Protein Expr.Purif., 80, 2011
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8STE
 | | Cryo-EM structure of NKCC1 Fu_CTD | | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | | Authors: | Moseng, M.A. | | Deposit date: | 2023-05-10 | | Release date: | 2023-05-17 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.34 Å) | | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
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7SFL
 | | Human NKCC1 state Fu-II | | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | | Authors: | Moseng, M.A. | | Deposit date: | 2021-10-04 | | Release date: | 2022-09-28 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.87 Å) | | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
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7SMP
 | | CryoEM structure of NKCC1 Bu-I | | Descriptor: | 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, POTASSIUM ION, Solute carrier family 12 member 2 | | Authors: | Moseng, M.A. | | Deposit date: | 2021-10-26 | | Release date: | 2022-09-28 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
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6OR2
 | | MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine | | Descriptor: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, DODECYL-BETA-D-MALTOSIDE, Membrane protein, ... | | Authors: | Su, C.-C. | | Deposit date: | 2019-04-29 | | Release date: | 2019-05-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7N6B
 | | Structure of MmpL3 reconstituted into lipid nanodisc in the TMM bound state | | Descriptor: | 6-O-[(2S)-2-{(1S)-18-[(1R,2R)-2-hexylcyclopropyl]-1-hydroxyoctadecyl}tricosanoyl]-alpha-D-glucopyranosyl alpha-D-glucopyranoside, MmpL3 transporter | | Authors: | Su, C.C, Yu, E. | | Deposit date: | 2021-06-08 | | Release date: | 2021-09-01 | | Method: | ELECTRON MICROSCOPY (2.66 Å) | | Cite: | Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport.
Plos Biol., 19, 2021
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7MXO
 | | CryoEM structure of human NKCC1 | | Descriptor: | CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 2 | | Authors: | Moseng, M.A. | | Deposit date: | 2021-05-19 | | Release date: | 2022-09-28 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
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7N3N
 | | CryoEM structure of human NKCC1 state Fu-I | | Descriptor: | 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2 | | Authors: | Moseng, M.A. | | Deposit date: | 2021-06-01 | | Release date: | 2022-09-28 | | Last modified: | 2023-05-31 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
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7K8B
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7K8C
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7K8A
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7K8D
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7K7M
 | | Crystal Structure of a membrane protein | | Descriptor: | Drug exporters of the RND superfamily-like protein, alpha-D-glucopyranose-(1-1)-6-O-decanoyl-alpha-D-glucopyranose | | Authors: | Su, C.-C. | | Deposit date: | 2020-09-23 | | Release date: | 2021-09-22 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.33 Å) | | Cite: | Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport.
Plos Biol., 19, 2021
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