3IPS
 
 | | X-ray structure of benzisoxazole synthetic agonist bound to the LXR-alpha | | 分子名称: | Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, SULFATE ION, ... | | 著者 | Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. | | 登録日 | 2009-08-18 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling.
J.Mol.Biol., 399, 2010
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3IPU
 | | X-ray structure of benzisoxazole urea synthetic agonist bound to the LXR-alpha | | 分子名称: | 4-{[methyl(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)carbamoyl]amino}benzoic acid, Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, ... | | 著者 | Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. | | 登録日 | 2009-08-18 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling.
J.Mol.Biol., 399, 2010
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3IPQ
 | | X-ray structure of GW3965 synthetic agonist bound to the LXR-alpha | | 分子名称: | Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, SULFATE ION, ... | | 著者 | Fradera, X, Vu, D, Nimz, O, Skene, R, Hosfield, D, Wijnands, R, Cooke, A.J, Haunso, A, King, A, Bennet, D.J, McGuire, R, Uitdehaag, J.C.M. | | 登録日 | 2009-08-18 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling.
J.Mol.Biol., 399, 2010
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5KVL
 | | Humanized 10G4 anti-leukotriene C4 antibody Fab fragment in complex with leukotriene C4 | | 分子名称: | (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-( 2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Huxford, T, King, A, Fleming, J.K, Wojciak, J.M. | | 登録日 | 2016-07-14 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Humanized 10G4 anti-leukotriene C4 antibody Fab fragment in complex with leukotriene C4
To Be Published
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2WZR
 | | The Structure of Foot and Mouth Disease Virus Serotype SAT1 | | 分子名称: | POLYPROTEIN | | 著者 | Adams, P, Lea, S, Newman, J, Blakemore, W, King, A, Stuart, D, Fry, E. | | 登録日 | 2009-12-02 | | 公開日 | 2010-12-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The Structure of Foot-and-Mouth Disease Virus Serotype Sat1.
To be Published
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2LXH
 | | NMR structure of the RING domain in ubiquitin ligase gp78 | | 分子名称: | E3 ubiquitin-protein ligase AMFR, ZINC ION | | 著者 | Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. | | 登録日 | 2012-08-27 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
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2LXP
 | | NMR structure of two domains in ubiquitin ligase gp78, RING and G2BR, bound to its conjugating enzyme Ube2g | | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2, ZINC ION | | 著者 | Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. | | 登録日 | 2012-08-30 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
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2LVN
 | | Structure of the gp78 CUE domain | | 分子名称: | E3 ubiquitin-protein ligase AMFR | | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | | 登録日 | 2012-07-09 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012
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2LVO
 | | Structure of the gp78CUE domain bound to monubiquitin | | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | | 登録日 | 2012-07-09 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012
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2LVP
 | | gp78CUE domain bound to the distal ubiquitin of K48-linked diubiquitin | | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | | 登録日 | 2012-07-09 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012
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2LVQ
 | | gp78CUE domain bound to the proximal ubiquitin of K48-linked diubiquitin | | 分子名称: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | | 著者 | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | | 登録日 | 2012-07-09 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012
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1TAM
 | | HUMAN IMMUNODEFICIENCY VIRUS, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | HIV-1 MATRIX PROTEIN | | 著者 | Matthews, S, Barlow, P, Clark, N, Kingsman, S, Kingsman, A, Campbell, I. | | 登録日 | 1996-02-07 | | 公開日 | 1996-07-11 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Refined solution structure of p17, the HIV matrix protein.
Biochem.Soc.Trans., 23, 1995
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1HEK
 | | Crystal structure of equine infectious anaemia virus matrix antigen (EIAV MA) | | 分子名称: | GAG POLYPROTEIN, CORE PROTEIN P15 | | 著者 | Hatanaka, H, Iourin, O, Rao, Z, Fry, E, Kingsman, A, Stuart, D.I. | | 登録日 | 2000-11-24 | | 公開日 | 2001-11-23 | | 最終更新日 | 2019-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of Equine Infectious Anemia Virus Matrix Protein.
J.Virol., 76, 2002
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1MN8
 | | Structure of Moloney Murine Leukaemia Virus Matrix Protein | | 分子名称: | Core protein p15 | | 著者 | Riffel, N, Harlos, K, Iourin, O, Rao, Z, Kingsman, A, Stuart, D, Fry, E. | | 登録日 | 2002-09-05 | | 公開日 | 2003-01-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Atomic resolution structure of Moloney murine leukaemia virus matrix protein and its relationship to other retroviral matrix proteins.
Structure, 10, 2002
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1SKV
 | | Crystal Structure of D-63 from Sulfolobus Spindle Virus 1 | | 分子名称: | Hypothetical 7.5 kDa protein | | 著者 | Kraft, P, Kummel, D, Oeckinghaus, A, Gauss, G.H, Wiedenheft, B, Young, M, Lawrence, C.M. | | 登録日 | 2004-03-05 | | 公開日 | 2004-07-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of d-63 from sulfolobus spindle-shaped virus 1: surface properties of the dimeric four-helix bundle suggest an adaptor protein function
J.Virol., 78, 2004
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1TBX
 | | Crystal structure of SSV1 F-93 | | 分子名称: | Hypothetical 11.0 kDa protein | | 著者 | Kraft, P, Oeckinghaus, A, Kummel, D, Gauss, G.H, Wiedenheft, B, Young, M, Lawrence, C.M. | | 登録日 | 2004-05-20 | | 公開日 | 2004-07-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of F-93 from Sulfolobus spindle-shaped virus 1, a winged-helix DNA binding protein.
J.Virol., 78, 2004
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3KWB
 | | Structure of CatK covalently bound to a dioxo-triazine inhibitor | | 分子名称: | 3,5-dioxo-4-(3-piperidin-1-ylpropyl)-2-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile, Cathepsin K | | 著者 | Uitdehaag, J.C.M, van Zeeland, M. | | 登録日 | 2009-12-01 | | 公開日 | 2010-04-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Dioxo-triazines as a novel series of cathepsin K inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
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1QQP
 | | FOOT-AND-MOUTH DISEASE VIRUS/ OLIGOSACCHARIDE RECEPTOR COMPLEX. | | 分子名称: | 2-O-sulfo-alpha-L-gulopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-gulopyranuronic acid, PROTEIN (GENOME POLYPROTEIN) | | 著者 | Fry, E.E, Lea, S.M, Jackson, T, Newman, J.W.I, Ellard, F.M, Blakemore, W.E, Abu-Ghazaleh, R, Samuel, A, King, A.M.Q, Stuart, D.I. | | 登録日 | 1999-05-20 | | 公開日 | 1999-06-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex.
EMBO J., 18, 1999
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5FCS
 | | Diabody | | 分子名称: | Diabody, SULFATE ION | | 著者 | Mosyak, L, Root, A. | | 登録日 | 2015-12-15 | | 公開日 | 2016-12-14 | | 最終更新日 | 2019-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer.
Antibodies, 5, 2016
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1FOD
 | | STRUCTURE OF A MAJOR IMMUNOGENIC SITE ON FOOT-AND-MOUTH DISEASE VIRUS | | 分子名称: | FOOT AND MOUTH DISEASE VIRUS | | 著者 | Logan, D.T, Lea, S, Lewis, R, Stuart, D, Fry, E. | | 登録日 | 1993-10-27 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of a major immunogenic site on foot-and-mouth disease virus.
Nature, 362, 1993
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1FMD
 | | THE STRUCTURE AND ANTIGENICITY OF A TYPE C FOOT-AND-MOUTH DISEASE VIRUS | | 分子名称: | FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP1), FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP2), FOOT-AND-MOUTH DISEASE VIRUS (SUBUNIT VP3), ... | | 著者 | Lea, S, Fry, E, Stuart, D. | | 登録日 | 1994-02-10 | | 公開日 | 1994-08-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The structure and antigenicity of a type C foot-and-mouth disease virus.
Structure, 2, 1994
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4LAD
 | | Crystal Structure of the Ube2g2:RING-G2BR complex | | 分子名称: | E3 ubiquitin-protein ligase AMFR, OXALATE ION, Ubiquitin-conjugating enzyme E2 G2, ... | | 著者 | Liang, Y.-H, Li, J, Das, R, Byrd, R.A, Ji, X. | | 登録日 | 2013-06-19 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
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1QGC
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4GH4
 | | Crystal Structure of Foot and Mouth Disease Virus A22 Serotype | | 分子名称: | capsid protein VP1, capsid protein VP2, capsid protein VP3, ... | | 著者 | Kotecha, A, Jinshan, R, Curry, S, Fry, E, Stuart, D. | | 登録日 | 2012-08-07 | | 公開日 | 2013-02-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Perturbations in the surface structure of A22 Iraq foot-and-mouth disease virus accompanying coupled changes in host cell specificity and antigenicity.
Structure, 4, 1996
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7M2N
 | | Crystal structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 | | 分子名称: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 5-[(5'-{1-(4-carboxy-1,3-thiazol-2-yl)-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-3-yl}-2'-fluoro[1,1'-biphenyl]-4-yl)oxy]-1H-1,2,3-triazole-4-carboxylic acid, ... | | 著者 | Gumpena, R, Ding, J, Powell, D.A, Lowther, W.T. | | 登録日 | 2021-03-17 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria
ACS Medicinal Chemistry Letters, 12, 2021
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