6B1Q
 
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6B1R
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8DLF
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6IJR
 | | Human PPARgamma ligand binding domain complexed with SB1495 | | Descriptor: | 16 mer peptide from Nuclear receptor coactivator 1, N-{[3-({[(1S,2R)-2-{[(2E)-2-cyano-4,4-dimethylpent-2-enoyl]amino}cyclopentyl]oxy}methyl)phenyl]methyl}-4-[(4-methylpiperazin-1-yl)methyl]benzamide, Peroxisome proliferator-activated receptor gamma | | Authors: | Jang, J.Y, Han, B.W. | | Deposit date: | 2018-10-11 | | Release date: | 2019-10-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPAR gamma phosphorylation.
Sci Rep, 9, 2019
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6IJS
 | | Human PPARgamma ligand binding domain complexed with SB1494 | | Descriptor: | 16-mer peptide from Nuclear receptor coactivator 1, N-{[3-({[(1R,2S)-2-{[(2E)-2-cyano-4,4-dimethylpent-2-enoyl]amino}cyclopentyl]oxy}methyl)phenyl]methyl}-4-[(4-methylpiperazin-1-yl)methyl]benzamide, Peroxisome proliferator-activated receptor gamma | | Authors: | Jang, J.Y, Han, B.W. | | Deposit date: | 2018-10-11 | | Release date: | 2019-10-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPAR gamma phosphorylation.
Sci Rep, 9, 2019
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6IY6
 | | Crystal structure of human cytosolic aspartyl-tRNA synthetase (DRS) in complex with glutathion-S transferase (GST) domains from Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) and glutamyl-prolyl-tRNA synthetase (EPRS) | | Descriptor: | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Aspartate--tRNA ligase, cytoplasmic, ... | | Authors: | Park, S.H, Hahn, H, Han, B.W. | | Deposit date: | 2018-12-13 | | Release date: | 2019-09-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | The DRS-AIMP2-EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex.
Iucrj, 6, 2019
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6JQ7
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6KZB
 | | Transglutaminase2 complexed with calcium | | Descriptor: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase 2 | | Authors: | Park, H.H, Kim, C.M. | | Deposit date: | 2019-09-23 | | Release date: | 2020-12-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.55 Å) | | Cite: | Competitive Binding of Magnesium to Calcium Binding Sites Reciprocally Regulates Transamidase and GTP Hydrolysis Activity of Transglutaminase 2.
Int J Mol Sci, 21, 2020
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6A0H
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6A0F
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6A0I
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6A0E
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5U9M
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6L4G
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6L4H
 | | Crystal structure of human NDRG3 C30S mutant | | Descriptor: | Protein NDRG3 | | Authors: | Kim, K.R, Han, B.W. | | Deposit date: | 2019-10-16 | | Release date: | 2020-08-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein.
Biomolecules, 10, 2020
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6L4B
 | | Crystal structure of human WT NDRG3 | | Descriptor: | Protein NDRG3 | | Authors: | Kim, K.R, Han, B.W. | | Deposit date: | 2019-10-16 | | Release date: | 2020-08-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein.
Biomolecules, 10, 2020
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7K01
 | | Structure of TFIIH in TFIIH/Rad4-Rad23-Rad33 DNA opening complex | | Descriptor: | DNA repair helicase RAD25, DNA repair helicase RAD3, General transcription and DNA repair factor IIH subunit SSL1, ... | | Authors: | van Eeuwen, T, Min, J.H, Murakami, K. | | Deposit date: | 2020-09-02 | | Release date: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.
Nat Commun, 12, 2021
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7K04
 | | Structure of TFIIH/Rad4-Rad23-Rad33/DNA in DNA opening | | Descriptor: | CALCIUM ION, DNA repair helicase RAD25, DNA repair helicase RAD3, ... | | Authors: | van Eeuwen, T, Min, J.H, Murakami, K. | | Deposit date: | 2020-09-03 | | Release date: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (9.25 Å) | | Cite: | Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.
Nat Commun, 12, 2021
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6MIH
 | | Crystal structure of host-guest complex with PC hachimoji DNA | | Descriptor: | DNA (5'-D(*CP*TP*TP*AP*(1WA)P*CP*(DB)P*T)-3'), DNA (5'-D(P*AP*(DS)P*GP*(1W5)P*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase | | Authors: | Georgiadis, M.M. | | Deposit date: | 2018-09-19 | | Release date: | 2019-02-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
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6MIG
 | | Crystal structure of host-guest complex with PB hachimoji DNA | | Descriptor: | DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), Gag-Pol polyprotein | | Authors: | Georgiadis, M.M. | | Deposit date: | 2018-09-19 | | Release date: | 2019-02-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
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6MIK
 | | Crystal structure of host-guest complex with PP hachimoji DNA | | Descriptor: | DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase | | Authors: | Georgiadis, M.M. | | Deposit date: | 2018-09-19 | | Release date: | 2019-02-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
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7KUE
 | | CryoEM structure of Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Cyclin CCL1, ... | | Authors: | van Eeuwen, T, Murakami, K, Li, T, Tsai, K.L. | | Deposit date: | 2020-11-24 | | Release date: | 2021-04-28 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure of TFIIK for phosphorylation of CTD of RNA polymerase II.
Sci Adv, 7, 2021
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7JTH
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7M2U
 | | Nucleotide Excision Repair complex TFIIH Rad4-33 | | Descriptor: | CALCIUM ION, DNA repair helicase RAD25, DNA repair helicase RAD3, ... | | Authors: | van Eeuwen, T, Murakami, K. | | Deposit date: | 2021-03-17 | | Release date: | 2021-07-28 | | Method: | ELECTRON MICROSCOPY (8.2 Å) | | Cite: | Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.
Nat Commun, 12, 2021
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7MKA
 | | Structure of EC+EC (leading EC-focused) | | Descriptor: | DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Yang, C, Murakami, K. | | Deposit date: | 2021-04-22 | | Release date: | 2022-04-27 | | Last modified: | 2023-05-17 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
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