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6XGC
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BU of 6xgc by Molmil
CryoEM structure of influenza hemagglutinin A/Michigan/45/2015 in complex with cyno antibody 1C4
分子名称: 1C4 Fab heavy chain, 1C4 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Qiu, Y, Zhou, Y.
登録日2020-06-17
公開日2021-03-10
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.
Sci Transl Med, 13, 2021
7S08
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BU of 7s08 by Molmil
Crystal structure of Epstein-Barr virus gH/gL targeting antibody 770F7
分子名称: 770F7 Fab Heavy chain, 770F7 Fab Light chain, GLYCEROL
著者Chen, W.-H, Joyce, M.G.
登録日2021-08-30
公開日2022-11-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.
Immunity, 55, 2022
4ZPV
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BU of 4zpv by Molmil
Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D12 Fab Heavy chain, D12 Fab light chain, ...
著者Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
登録日2015-05-08
公開日2015-10-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Evaluation of candidate vaccine approaches for MERS-CoV.
Nat Commun, 6, 2015
4ZPW
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BU of 4zpw by Molmil
Structure of unbound MERS-CoV spike receptor-binding domain (England1 strain).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Spike glycoprotein
著者Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
登録日2015-05-08
公開日2015-08-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.023 Å)
主引用文献Evaluation of candidate vaccine approaches for MERS-CoV.
Nat Commun, 6, 2015
5W23
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BU of 5w23 by Molmil
Crystal Structure of RSV F in complex with 5C4 Fab
分子名称: 5C4 Fab heavy chain, 5C4 Fab light chain, Fusion glycoprotein F0, ...
著者Battles, M.B, McLellan, J.S.
登録日2017-06-05
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.
Nat Commun, 8, 2017
5W24
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BU of 5w24 by Molmil
Crystal Structure of 5C4 Fab
分子名称: (R,R)-2,3-BUTANEDIOL, 5C4 Fab Heavy Chain, 5C4 Fab Light Chain
著者Battles, M.B, McLellan, J.S, Taher, N.M.
登録日2017-06-05
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein.
Nat Commun, 8, 2017
6B5P
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BU of 6b5p by Molmil
Structure of PfCSP peptide 20 with human antibody CIS42
分子名称: CIS42 Fab Heavy chain, CIS42 Fab Light chain, pfCSP peptide 20: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (2.297 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5R
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BU of 6b5r by Molmil
Structure of PfCSP peptide 21 with human antibody CIS42
分子名称: CIS42 Fab Heavy chain, CIS42 Fab Light chain, PfCSP peptide 21: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (1.775 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5M
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BU of 6b5m by Molmil
Structure of PfCSP peptide 21 with human protective antibody CIS43
分子名称: 1,2-ETHANEDIOL, CIS43 Fab Heavy chain, CIS43 Fab Light chain, ...
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5T
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BU of 6b5t by Molmil
Structure of PfCSP peptide 29 with human antibody CIS42
分子名称: AMMONIUM ION, CIS42 Fab Heavy chain, CIS42 Fab Light chain, ...
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (2.222 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5N
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BU of 6b5n by Molmil
Structure of PfCSP peptide 25 with human protective antibody CIS43
分子名称: CIS43 Fab Heavy chain, CIS43 Fab Light chain, pfCSP peptide 25: ASN-VAL-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5O
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BU of 6b5o by Molmil
Structure of PfCSP peptide 29 with human protective antibody CIS43
分子名称: CIS43 Fab Heavy chain, CIS43 Fab Light chain, PfCSP peptide 29: ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-ASN
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5L
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BU of 6b5l by Molmil
Structure of PfCSP peptide 20 with human protective antibody CIS43
分子名称: CIS43 Fab Heavy chain, CIS43 Fab Light Chain, PfCSP peptide 20: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5S
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BU of 6b5s by Molmil
Structure of PfCSP peptide 25 with human antibody CIS42
分子名称: AMMONIUM ION, CIS42 Fab Heavy chain, CIS42 Fab Light chain, ...
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2019-01-09
実験手法X-RAY DIFFRACTION (1.983 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
5TOJ
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BU of 5toj by Molmil
Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ...
著者Gilman, M.S.A, Kabeche, S.C, McLellan, J.S.
登録日2016-10-17
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
5TP3
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BU of 5tp3 by Molmil
Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4
分子名称: F-VHH-4
著者Wrapp, D, Gilman, M.S.A, McLellan, J.S.
登録日2016-10-19
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.874 Å)
主引用文献Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
5TOK
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BU of 5tok by Molmil
Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-L66
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ...
著者Gilman, M.S.A, Kabeche, S.C, McLellan, J.S.
登録日2016-10-17
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
6VFH
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BU of 6vfh by Molmil
De novo designed tetrahedral nanoparticle T33_dn10
分子名称: T33_dn10A, T33_dn10B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFJ
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BU of 6vfj by Molmil
De novo designed icosahedral nanoparticle I53_dn5
分子名称: I53_dn5A, I53_dn5B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.35 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFI
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BU of 6vfi by Molmil
De novo designed octahedral nanoparticle O43_dn18
分子名称: O43_dn18A, O43_dn18B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-08-12
最終更新日2020-08-19
実験手法ELECTRON MICROSCOPY (4.54 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6V8E
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BU of 6v8e by Molmil
Computationally designed C3-symmetric homotrimer from TPR repeat protein
分子名称: Designed protein
著者Sankaran, B, Ueda, G, Zwart, P.H, Baker, D.
登録日2019-12-10
公開日2020-08-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VEH
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BU of 6veh by Molmil
Computationally designed C3-symmetric homotrimer from HEAT repeat protein
分子名称: HEAT repeat domain-containing protein
著者Bick, M.J, Ueda, G, Baker, D.
登録日2020-01-02
公開日2020-08-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
5C0S
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BU of 5c0s by Molmil
Crystal structure of a generation 4 influenza hemagglutinin stabilized stem in complex with the broadly neutralizing antibody CR6261
分子名称: CR6261 antibody heavy chain, CR6261 antibody light chain, Hemagglutinin, ...
著者Boyington, J.C, Kwong, P.D, Nabel, G.J, Mascola, J.R.
登録日2015-06-12
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection.
Nat. Med., 21, 2015
5C0R
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BU of 5c0r by Molmil
Crystal Structure of a Generation 3 Influenza Hemagglutinin Stabilized Stem Complexed with the Broadly Neutralizing Antibody C179
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C179 Fab heavy chain, ...
著者Boyington, J.C, kwong, P.D, Nabel, G.J, Mascola, J.R.
登録日2015-06-12
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.188 Å)
主引用文献Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection.
Nat. Med., 21, 2015
8UR7
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BU of 8ur7 by Molmil
I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-6heptad-I53_dn5 (local refinement of TH-6heptad)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Trimer head HA,Hemagglutinin HA1 chain
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-10-25
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Antigen spacing on protein nanoparticles influences antibody responses to vaccination.
Cell Rep, 42, 2023

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