7OPB
 
 | | IL7R in complex with an antagonist | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ... | | 著者 | Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N. | | 登録日 | 2021-05-31 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.144 Å) | | 主引用文献 | Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
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5IWL
 | | CD47-diabody complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5F9 diabody, Leukocyte surface antigen CD47, ... | | 著者 | Di, W, Jude, K.M, Garcia, K.C. | | 登録日 | 2016-03-22 | | 公開日 | 2016-06-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer.
J.Clin.Invest., 126, 2016
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7N1J
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7N1K
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5E4E
 | | Engineered Interleukin-13 bound to receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ... | | 著者 | Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C. | | 登録日 | 2015-10-05 | | 公開日 | 2015-12-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.
Sci.Signal., 8, 2015
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7RKF
 | | Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody fragment scFv16, Fractalkine, ... | | 著者 | Tsutsumi, N, Maeda, S, Qu, Q, Skiniotis, G, Kobilka, B.K, Garcia, K.C. | | 登録日 | 2021-07-22 | | 公開日 | 2022-01-26 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
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7RDH
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7S5B
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7UQC
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4Y5Y
 | | Diabody 330 complex with EpoR | | 分子名称: | Erythropoietin receptor, GLYCEROL, diabody 330 VH domain, ... | | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | | 登録日 | 2015-02-12 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
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4Y5X
 | | Diabody 305 complex with EpoR | | 分子名称: | CITRATE ANION, DI(HYDROXYETHYL)ETHER, Erythropoietin receptor, ... | | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | | 登録日 | 2015-02-12 | | 公開日 | 2015-03-18 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
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4Y5V
 | | Diabody 305 complex with EpoR | | 分子名称: | DI(HYDROXYETHYL)ETHER, Diabody 305 VL domain, Erythropoietin receptor, ... | | 著者 | Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C. | | 登録日 | 2015-02-12 | | 公開日 | 2015-04-29 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
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5UN6
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