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5UN6
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BU of 5un6 by Molmil
Frizzled-8 complex with designed surrogate Wnt agonist, A1 dataset
Descriptor: Designed Wnt agonist B12, Frizzled-8
Authors:Janda, C.Y, Garcia, K.C, Jude, K.M.
Deposit date:2017-01-30
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling.
Nature, 545, 2017
7RKF
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BU of 7rkf by Molmil
Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody fragment scFv16, Fractalkine, ...
Authors:Tsutsumi, N, Maeda, S, Qu, Q, Skiniotis, G, Kobilka, B.K, Garcia, K.C.
Deposit date:2021-07-22
Release date:2022-01-26
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RDH
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BU of 7rdh by Molmil
Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ...
Authors:Kadam, R.U, Wilson, I.A.
Deposit date:2021-07-09
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7S5B
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BU of 7s5b by Molmil
Unbound State of a De novo designed Protein Binder to the Human Interleukin-7 Receptor
Descriptor: Miniprotein Binder
Authors:Walsh, S.T.R, Cao, L, Baker, D.
Deposit date:2021-09-10
Release date:2022-05-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7N1J
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BU of 7n1j by Molmil
Crystal structure of FGFR4 domain 3 in complex with a de novo-designed mini-binder
Descriptor: Binder, Fibroblast growth factor receptor 4
Authors:Park, J.S, Lee, S.
Deposit date:2021-05-27
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7N1K
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BU of 7n1k by Molmil
Crystal structure of a de novo-designed mini-protein targeting FGFR
Descriptor: Binder
Authors:Park, J.S, Lee, S.
Deposit date:2021-05-27
Release date:2022-04-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
7OPB
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BU of 7opb by Molmil
IL7R in complex with an antagonist
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ...
Authors:Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N.
Deposit date:2021-05-31
Release date:2022-05-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.144 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
4Y5Y
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BU of 4y5y by Molmil
Diabody 330 complex with EpoR
Descriptor: Erythropoietin receptor, GLYCEROL, diabody 330 VH domain, ...
Authors:Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
Deposit date:2015-02-12
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
4Y5X
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BU of 4y5x by Molmil
Diabody 305 complex with EpoR
Descriptor: CITRATE ANION, DI(HYDROXYETHYL)ETHER, Erythropoietin receptor, ...
Authors:Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
Deposit date:2015-02-12
Release date:2015-03-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
4Y5V
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BU of 4y5v by Molmil
Diabody 305 complex with EpoR
Descriptor: DI(HYDROXYETHYL)ETHER, Diabody 305 VL domain, Erythropoietin receptor, ...
Authors:Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
Deposit date:2015-02-12
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
7UQC
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BU of 7uqc by Molmil
phospho-GlialCAM peptide AA370-389 with Fab MS39p2w174
Descriptor: CHLORIDE ION, Fab MS39p2w174 Heavy Chain, Fab MS39p2w174 Light Chain, ...
Authors:Lanz, T.V, Robinson, W.H, Fernandez, D.
Deposit date:2022-04-19
Release date:2023-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Evolution of Antibody Reactivity against EBV EBNA1 to Molecular Mimicry with GlialCAM
To Be Published

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PDB entries from 2024-05-01

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