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7CPV
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BU of 7cpv by Molmil
Cryo-EM structure of 80S ribosome from mouse testis
Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ...
Authors:Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H.
Deposit date:2020-08-08
Release date:2022-02-02
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:A male germ-cell-specific ribosome controls male fertility.
Nature, 612, 2022
7CPU
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BU of 7cpu by Molmil
Cryo-EM structure of 80S ribosome from mouse kidney
Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ...
Authors:Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H.
Deposit date:2020-08-08
Release date:2022-02-02
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:A male germ-cell-specific ribosome controls male fertility.
Nature, 612, 2022
7XWY
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BU of 7xwy by Molmil
Crystal structure of spFft3 N-terminal truncation
Descriptor: ATP-dependent helicase fft3, SULFATE ION
Authors:Zhang, N, Jiang, T, Huo, Y.
Deposit date:2022-05-27
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of spFft3 N-terminal truncation
To Be Published
7YND
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BU of 7ynd by Molmil
Cryo-EM structure of Cas7-11-crRNA-Csx29 ternary complex
Descriptor: CHAT domain-containing protein, CRISPR-associated RAMP family protein, crRNA (38-MER)
Authors:Huo, Y, Dong, Q, Zhao, H, Jiang, T.
Deposit date:2022-07-30
Release date:2023-02-01
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Nat Microbiol, 8, 2023
7YN9
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BU of 7yn9 by Molmil
Cryo-EM structure of Cas7-11-crRNA binary complex
Descriptor: CRISPR-associated RAMP family protein, crRNA
Authors:Huo, Y, Dong, Q, Zhao, H, Jiang, T.
Deposit date:2022-07-30
Release date:2023-02-01
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Nat Microbiol, 8, 2023
7YNA
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BU of 7yna by Molmil
Cryo-EM structure of Cas7-11-crRNA bound to target RNA-1
Descriptor: CRISPR-associated RAMP family protein, Target RNA-1 (25-MER), crRNA (38-MER)
Authors:Huo, Y, Dong, Q, Zhao, H, Jiang, T.
Deposit date:2022-07-30
Release date:2023-02-01
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Nat Microbiol, 8, 2023
7YNB
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BU of 7ynb by Molmil
Cryo-EM structure of Cas7-11-crRNA bound to target RNA-2
Descriptor: CRISPR-associated RAMP family protein, Target RNA-2 (28-MER), crRNA (38-MER)
Authors:Huo, Y, Dong, Q, Zhao, H, Jiang, T.
Deposit date:2022-07-30
Release date:2023-02-01
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Nat Microbiol, 8, 2023
7YNC
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BU of 7ync by Molmil
Cryo-EM structure of Cas7-11-crRNA bound to target RNA-3
Descriptor: CRISPR-associated RAMP family protein, Target RNA-3 (28-MER), crRNA (38-MER)
Authors:Huo, Y, Dong, Q, Zhao, H, Jiang, T.
Deposit date:2022-07-30
Release date:2023-02-01
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Nat Microbiol, 8, 2023
2HVC
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BU of 2hvc by Molmil
The Crystal Structure of Ligand-binding Domain (LBD) of human Androgen Receptor in Complex with a selective modulator LGD2226
Descriptor: 6-[BIS(2,2,2-TRIFLUOROETHYL)AMINO]-4-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE, Androgen receptor
Authors:Wang, F, Liu, X.-Q, Li, H, Liang, K.-N, Miner, J.N, Hong, M, Kallel, E.A, van Oeveren, A, Zhi, L, Jiang, T.
Deposit date:2006-07-28
Release date:2007-07-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
6KFM
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BU of 6kfm by Molmil
Amino-transferase (AMT) Domain of Hybrid Polyketide/Non-Ribosomal Peptide Synthetase
Descriptor: GLYCEROL, Mycosubtilin synthase subunit A, PYRIDOXAL-5'-PHOSPHATE
Authors:Tian, Q.W, Jiang, T.
Deposit date:2019-07-08
Release date:2019-09-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure Insights into the Molecular Mechanism of Two Tailoring Domains of Hybrid Polyketide/Non-Ribosomal Peptide Synthetase
To Be Published
6KFR
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BU of 6kfr by Molmil
Amino-transferase (AMT) Domain - Arg Complex of Hybrid Polyketide/Non-Ribosomal Peptide Synthetase
Descriptor: ARGININE, Mycosubtilin synthase subunit A, PYRIDOXAL-5'-PHOSPHATE
Authors:Tian, Q.W, Jiang, T.
Deposit date:2019-07-08
Release date:2019-09-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure Insights into the Molecular Mechanism of Two Tailoring Domains of Hybrid Polyketide/Non-Ribosomal Peptide Synthetase
To Be Published
6KFU
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BU of 6kfu by Molmil
A ACP-AMT Fusion Protein of Hybrid Polyketide/Non-Ribosomal Peptide Synthetase
Descriptor: GLYCEROL, Mycosubtilin synthase subunit A,Mycosubtilin synthase subunit A, PYRIDOXAL-5'-PHOSPHATE
Authors:Tian, Q.W, Jiang, T.
Deposit date:2019-07-08
Release date:2019-09-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure Insights into the Molecular Mechanism of Two Tailoring Domains of Hybrid Polyketide/Non-Ribosomal Peptide Synthetase
To Be Published
6KET
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BU of 6ket by Molmil
Flavin-utilizing Monooxygenase (OX) Domain of Hybrid Polyketide/Non-Ribosomal Peptide Synthetase
Descriptor: PuwE
Authors:Tian, Q.W, Jiang, T.
Deposit date:2019-07-05
Release date:2019-09-25
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure Insights into the Molecular Mechanism of Two Tailoring Domains of Hybrid Polyketide/Non-Ribosomal Peptide Synthetase
To Be Published
5Y62
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BU of 5y62 by Molmil
YfiR complexed with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, YfiR
Authors:Zhou, L, Xu, M, Jiang, T.
Deposit date:2017-08-10
Release date:2017-09-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into the functional role of GMP in modulating the YfiBNR system
Biochem. Biophys. Res. Commun., 493, 2017
5Y61
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BU of 5y61 by Molmil
YfiB-YfiR complexed with GMP
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, YfiB, YfiR
Authors:Zhou, L, Xu, M, Jiang, T.
Deposit date:2017-08-10
Release date:2017-09-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural insights into the functional role of GMP in modulating the YfiBNR system
Biochem. Biophys. Res. Commun., 493, 2017
5W5O
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BU of 5w5o by Molmil
Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases.
Descriptor: 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine, Receptor-interacting serine/threonine-protein kinase 2
Authors:Kreusch, A, Spraggon, G.
Deposit date:2017-06-15
Release date:2017-10-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017
5W5J
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BU of 5w5j by Molmil
Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases
Descriptor: N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 2, SULFATE ION
Authors:Kreusch, A, Spraggon, G.
Deposit date:2017-06-15
Release date:2017-10-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017
4Z55
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BU of 4z55 by Molmil
Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
Descriptor: ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Authors:Lee, C.C, Spraggon, G.
Deposit date:2015-04-02
Release date:2016-02-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
6V2J
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BU of 6v2j by Molmil
Crystal structure of ClC-ec1 triple mutant (E113Q, E148Q, E203Q)
Descriptor: CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA
Authors:Maduke, M, Mathews, I.I, Chavan, T.S.
Deposit date:2019-11-24
Release date:2020-05-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl - /H + transport cycle.
Elife, 9, 2020
4R8W
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BU of 4r8w by Molmil
Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a neutralizing antibody CT149
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of neutralizing antibody CT149, Hemagglutinin, ...
Authors:Wu, Y, Shi, Y, Qi, J, Gao, G.F.
Deposit date:2014-09-03
Release date:2015-08-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus
Nat Commun, 6, 2015
7CWO
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BU of 7cwo by Molmil
SARS-CoV-2 spike protein RBD and P17 fab complex
Descriptor: Spike glycoprotein, heavy chain of P17 Fab, light chain of P17 Fab
Authors:Wang, X, Wang, N.
Deposit date:2020-08-29
Release date:2020-12-16
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7CWL
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BU of 7cwl by Molmil
SARS-CoV-2 spike protein and P17 fab complex with one RBD in close state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab P17 heavy chain, Fab P17 light chain, ...
Authors:Wang, X, Wang, N.
Deposit date:2020-08-29
Release date:2021-01-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7CWM
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BU of 7cwm by Molmil
Complex of SARS-CoV-2 spike protein and Fab P17 with one RBD in open state and two RBD in closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P17 heavy chain, ...
Authors:Wang, N, Wang, X.
Deposit date:2020-08-29
Release date:2020-12-16
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
7CWN
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BU of 7cwn by Molmil
P17-H014 Fab cocktail in complex with SARS-CoV-2 spike protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Wang, N, Wang, X.
Deposit date:2020-08-29
Release date:2020-12-16
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
4UBD
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BU of 4ubd by Molmil
Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Shore, D.A, Yang, H, Cho, M, Donis, R.O, Stevens, J.
Deposit date:2014-08-12
Release date:2015-06-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus.
Nat Commun, 6, 2015

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