4MA7
 
 | | Crystal structure of mouse prion protein complexed with Promazine | | 分子名称: | Major prion protein, POM1 heavy chain, POM1 light chain, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2013-08-15 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural basis of prion inhibition by phenothiazine compounds.
Structure, 22, 2014
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4MA8
 | | Crystal structure of mouse prion protein complexed with Chlorpromazine | | 分子名称: | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, Major prion protein, POM1 heavy chain, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2013-08-15 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of prion inhibition by phenothiazine compounds.
Structure, 22, 2014
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4M1U
 | | The crystal structure of Stx2 and a disaccharide ligand | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-methyl beta-D-galactopyranoside, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Shiga toxin 2 A-subunit, ... | | 著者 | Yin, J, James, M.N.G, Jacobson, J.M, Kitov, P.I, Bundle, D.R, Mulvey, G, Armstrong, G. | | 登録日 | 2013-08-04 | | 公開日 | 2013-11-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | The crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor.
J.Biol.Chem., 289, 2014
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4MJ4
 | | Human iduronidase apo structure P21 form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-L-iduronidase, CHLORIDE ION, ... | | 著者 | Bie, H, Yin, J, He, X, Kermode, A.R, Goddard-Borger, E.D, Withers, S.G, James, M.N.G. | | 登録日 | 2013-09-03 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.172 Å) | | 主引用文献 | Insights into mucopolysaccharidosis I from the structure and action of alpha-L-iduronidase.
Nat.Chem.Biol., 9, 2013
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4MJ2
 | | Crystal structure of apo-iduronidase in the R3 form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-L-iduronidase, ... | | 著者 | Bie, H, Yin, J, He, X, Kermode, A.R, Goddard-Borger, E.D, Withers, S.G, James, M.N.G. | | 登録日 | 2013-09-03 | | 公開日 | 2013-09-18 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Insights into mucopolysaccharidosis I from the structure and action of alpha-L-iduronidase.
Nat.Chem.Biol., 9, 2013
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2GTB
 | | Crystal structure of SARS coronavirus main peptidase (with an additional Ala at the N-terminus of each protomer) inhibited by an aza-peptide epoxide in the space group P43212 | | 分子名称: | (5S,8S,14R)-ETHYL 11-(3-AMINO-3-OXOPROPYL)-8-BENZYL-14-HYDROXY-5-ISOBUTYL-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,11-TETRAAZAPENTADECAN-15-OATE, 3C-like proteinase, ACETIC ACID | | 著者 | Lee, T.-W, Cherney, M.M, Huitema, C, Liu, J, James, K.E, Powers, J.C. | | 登録日 | 2006-04-27 | | 公開日 | 2006-12-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures Reveal an Induced-fit Binding of a Substrate-like Aza-peptide Epoxide to SARS Coronavirus Main Peptidase.
J.Mol.Biol., 366, 2007
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1YU6
 | | Crystal Structure of the Subtilisin Carlsberg:OMTKY3 Complex | | 分子名称: | CALCIUM ION, Ovomucoid, Subtilisin Carlsberg | | 著者 | Maynes, J.T, Cherney, M.M, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | 登録日 | 2005-02-11 | | 公開日 | 2005-05-03 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations.
Acta Crystallogr.,Sect.D, 61, 2005
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3SY4
 | | Crystal structure of sulfide:quinone oxidoreductase Ser126Ala variant from Acidithiobacillus ferrooxidans | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-15 | | 公開日 | 2012-05-16 | | 最終更新日 | 2012-06-13 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3SYI
 | | Crystal structure of sulfide:quinone oxidoreductase Ser126Ala variant from Acidithiobacillus ferrooxidans using 7.0 keV diffraction data | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-17 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2001 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3SZF
 | | Crystal structure of sulfide:quinone oxidoreductase H198A variant from Acidithiobacillus ferrooxidans in complex with bound trisulfide and decylubiquinone | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-18 | | 公開日 | 2012-05-16 | | 最終更新日 | 2014-05-07 | | 実験手法 | X-RAY DIFFRACTION (2.0994 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3SZW
 | | Crystal structure of sulfide:quinone oxidoreductase Cys128Ser variant from Acidithiobacillus ferrooxidans in complex with decylubiquinone | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-19 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3SX6
 | | Crystal structure of sulfide:quinone oxidoreductase Cys356Ala variant from Acidithiobacillus ferrooxidans complexed with decylubiquinone | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-14 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7955 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3SXI
 | | Crystal structure of sulfide:quinone oxidoreductase Cys128Ala variant from Acidithiobacillus ferrooxidans complexed with decylubiquinone | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-14 | | 公開日 | 2012-05-16 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1792 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3T2K
 | | Crystal structure of sulfide:quinone oxidoreductase Cys128Ala variant from Acidithiobacillus ferrooxidans with bound trisulfane | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-22 | | 公開日 | 2012-05-16 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3501 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3T0K
 | | Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans with bound trisulfide and decylubiquinone | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-20 | | 公開日 | 2012-05-16 | | 最終更新日 | 2014-05-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3SZ0
 | | Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans in complex with sodium selenide | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, SELENIUM ATOM, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-18 | | 公開日 | 2012-05-16 | | 最終更新日 | 2012-07-25 | | 実験手法 | X-RAY DIFFRACTION (2.1501 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3SZC
 | | Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans in complex with gold (I) cyanide | | 分子名称: | 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-18 | | 公開日 | 2012-05-16 | | 最終更新日 | 2013-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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3T2Y
 | | Crystal structure of sulfide:quinone oxidoreductase His132Ala variant from Acidithiobacillus ferrooxidans with bound disulfide | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-23 | | 公開日 | 2012-05-16 | | 最終更新日 | 2012-06-13 | | 実験手法 | X-RAY DIFFRACTION (2.5001 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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2ATO
 | | Crystal structure of Human Cathepsin K in complex with myocrisin | | 分子名称: | (S)-(1,2-DICARBOXYETHYLTHIO)GOLD, Cathepsin K, SULFATE ION | | 著者 | Weidauer, E, Yasuda, Y, Biswal, B.K, Kerr, L.D, Cherney, M.M, Gordon, R.E, James, M.N.G, Bromme, D. | | 登録日 | 2005-08-25 | | 公開日 | 2006-08-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S.
Biol.Chem., 388, 2007
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3T14
 | | Crystal structure of sulfide:quinone oxidoreductase Cys128Ala variant from Acidithiobacillus ferrooxidans with bound disulfide | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ... | | 著者 | Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. | | 登録日 | 2011-07-21 | | 公開日 | 2012-05-16 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
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2ZKU
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5ER2
 | | High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor. the analysis of the inhibitor binding and description of the rigid body shift in the enzyme | | 分子名称: | 6-ammonio-N-{[(2R,3R)-3-{[N-(tert-butoxycarbonyl)-L-phenylalanyl-3-(1H-imidazol-3-ium-4-yl)-L-alanyl]amino}-4-cyclohexyl-2-hydroxybutyl](2-methylpropyl)carbamoyl}-L-norleucyl-L-phenylalanine, ENDOTHIAPEPSIN | | 著者 | Sali, A, Veerapandian, B, Cooper, J.B, Foundling, S.I, Hoover, D.J, Blundell, T.L. | | 登録日 | 1991-01-02 | | 公開日 | 1991-04-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor: the analysis of the inhibitor binding and description of the rigid body shift in the enzyme.
EMBO J., 8, 1989
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3EI9
 | | Crystal structure of K270N variant of LL-diaminopimelate aminotransferase from Arabidopsis thaliana complexed with L-Glu: External aldimine form | | 分子名称: | (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-glutamic acid, GLYCEROL, LL-diaminopimelate aminotransferase, ... | | 著者 | Watanabe, N, Clay, M.D, van Belkum, M.J, Cherney, M.M, Vederas, J.C, James, M.N.G. | | 登録日 | 2008-09-15 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
J.Mol.Biol., 384, 2008
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3EI8
 | | Crystal structure of K270N variant of LL-diaminopimelate aminotransferase from Arabidopsis thaliana complexed with LL-DAP: External aldimine form | | 分子名称: | (2S,6S)-2-amino-6-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}heptanedioic acid, GLYCEROL, LL-diaminopimelate aminotransferase, ... | | 著者 | Watanabe, N, Clay, M.D, van Belkum, M.J, Cherney, M.M, Vederas, J.C, James, M.N.G. | | 登録日 | 2008-09-15 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
J.Mol.Biol., 384, 2008
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3EIB
 | | Crystal structure of K270N variant of LL-diaminopimelate aminotransferase from Arabidopsis thaliana | | 分子名称: | GLYCEROL, LL-diaminopimelate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Watanabe, N, Clay, M.D, van Belkum, M.J, Cherney, M.M, Vederas, J.C, James, M.N.G. | | 登録日 | 2008-09-15 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
J.Mol.Biol., 384, 2008
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