4M1U
The crystal structure of Stx2 and a disaccharide ligand
Summary for 4M1U
Entry DOI | 10.2210/pdb4m1u/pdb |
Related | 1BOS 1R4P |
Descriptor | Shiga toxin 2 A-subunit, Shiga toxin 2 B subunit, 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-4)-methyl beta-D-galactopyranoside, ... (5 entities in total) |
Functional Keywords | rrna n-glycosylase, hydrolase |
Biological source | Escherichia coli O157:H7 More |
Total number of polymer chains | 6 |
Total formula weight | 73749.64 |
Authors | Yin, J.,James, M.N.G.,Jacobson, J.M.,Kitov, P.I.,Bundle, D.R.,Mulvey, G.,Armstrong, G. (deposition date: 2013-08-04, release date: 2013-11-20, Last modification date: 2023-09-20) |
Primary citation | Jacobson, J.M.,Yin, J.,Kitov, P.I.,Mulvey, G.,Griener, T.P.,James, M.N.,Armstrong, G.,Bundle, D.R. The crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor. J.Biol.Chem., 289:885-894, 2014 Cited by PubMed: 24225957DOI: 10.1074/jbc.M113.518886 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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