8LPR
 
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7LPR
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5LPR
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4APE
 | | THE ACTIVE SITE OF ASPARTIC PROTEINASES | | 分子名称: | ENDOTHIAPEPSIN | | 著者 | Pearl, L.H, Sewell, B.T, Jenkins, J.A, Cooper, J.B, Blundell, T.L. | | 登録日 | 1986-06-09 | | 公開日 | 1986-07-14 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984
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1DS3
 | | CRYSTAL STRUCTURE OF OMTKY3-CH2-ASP19I | | 分子名称: | OVOMUCOID | | 著者 | Bateman, K.S, Huang, K, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | 登録日 | 2000-01-06 | | 公開日 | 2001-01-31 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
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1DS2
 | | CRYSTAL STRUCTURE OF SGPB:OMTKY3-COO-LEU18I | | 分子名称: | OVOMUCOID, PROTEINASE B (SGPB) | | 著者 | Bateman, K.S, Huang, K, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | 登録日 | 2000-01-06 | | 公開日 | 2001-01-31 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
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1EUD
 | | CRYSTAL STRUCTURE OF PHOSPHORYLATED PIG HEART, GTP-SPECIFIC SUCCINYL-COA SYNTHETASE | | 分子名称: | SUCCINYL-COA SYNTHETASE, ALPHA CHAIN, BETA CHAIN, ... | | 著者 | Fraser, M.E, James, M.N.G, Bridger, W.A, Wolodko, W.T. | | 登録日 | 2000-04-14 | | 公開日 | 2000-07-27 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase.
J.Mol.Biol., 299, 2000
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1EAI
 | | COMPLEX OF ASCARIS CHYMOTRPSIN/ELASTASE INHIBITOR WITH PORCINE ELASTASE | | 分子名称: | PROTEIN (CHYMOTRYPSIN/ELASTASE ISOINHIBITOR 1), PROTEIN (ELASTASE) | | 著者 | Huang, K, Strynadka, N.C.J, Bernard, V.D, Peanasky, R.J, James, M.N.G. | | 登録日 | 1999-03-25 | | 公開日 | 1999-04-05 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase.
Structure, 2, 1994
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1NFP
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3LPR
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3KPK
 | | Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans, C160A mutant | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ... | | 著者 | Cherney, M.M, Zhang, Y, Solomonson, M, Weiner, J.H, James, M.N.G. | | 登録日 | 2009-11-16 | | 公開日 | 2010-04-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans: insights into sulfidotrophic respiration and detoxification.
J.Mol.Biol., 398, 2010
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3LPN
 | | Crystal structure of the phosphoribosylpyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with an ATP analog (AMPCPP). | | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Ribose-phosphate pyrophosphokinase, SULFATE ION | | 著者 | Cherney, M.M, Cherney, L.T, Garen, C.R, James, M.N.G. | | 登録日 | 2010-02-05 | | 公開日 | 2011-02-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs.
J.Mol.Biol., 413, 2011
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3LAP
 | | The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-canavanine. | | 分子名称: | 5'-D(*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*A)-3', 5'-D(*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*A)-3', Arginine repressor, ... | | 著者 | Cherney, L.T, Cherney, M.M, Garen, C.R, James, M.N.G, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2010-01-06 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression.
J.Mol.Biol., 399, 2010
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3LAJ
 | | The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-arginine. | | 分子名称: | 5'-D(*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*A)-3', 5'-D(*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*A)-3', ARGININE, ... | | 著者 | Cherney, L.T, Cherney, M.M, Garen, C.R, James, M.N.G, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | | 登録日 | 2010-01-06 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.306 Å) | | 主引用文献 | crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression.
J.Mol.Biol., 399, 2010
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3LRT
 | | Crystal structure of the phosphoribosyl pyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with ADP. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Ribose-phosphate pyrophosphokinase, SULFATE ION | | 著者 | Cherney, M.M, Cherney, L.T, Garen, C.R, James, M.N.G. | | 登録日 | 2010-02-11 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | | 主引用文献 | The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs.
J.Mol.Biol., 413, 2011
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3MBI
 | | Crystal structure of the phosphoribosylpyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with ADP-Mg2+ and ribose 5-phosphate | | 分子名称: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Cherney, L.T, Cherney, M.M, Garen, C.R, James, M.N.G. | | 登録日 | 2010-03-25 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs.
J.Mol.Biol., 413, 2011
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3NAG
 | | Crystal structure of the phosphoribosylpyrophosphate (PRPP) synthetase from Thermoplasma Volcanium in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribose-phosphate pyrophosphokinase, ... | | 著者 | Cherney, M.M, Cherney, L.T, Garen, C.R, James, M.N.G. | | 登録日 | 2010-06-02 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs.
J.Mol.Biol., 413, 2011
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4YX2
 | | Crystal structure of Bovine prion protein complexed with POM1 FAB | | 分子名称: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2015-03-22 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.194 Å) | | 主引用文献 | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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4YXL
 | | Crystal structure of Syrian hamster prion protein complexed with POM1 FAB | | 分子名称: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2015-03-23 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | | 主引用文献 | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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4YXH
 | | Crystal structure of Deer prion protein complexed with POM1 FAB | | 分子名称: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2015-03-23 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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4YXK
 | | Crystal structure of Elk prion protein complexed with POM1 FAB | | 分子名称: | Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ... | | 著者 | Baral, P.K, Swayampakula, M, James, M.N.G. | | 登録日 | 2015-03-23 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
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4J8R
 | | Structure of an octapeptide repeat of the prion protein bound to the POM2 Fab antibody fragment | | 分子名称: | Heavy chain of POM2 Fab, Light chain of POM2 Fab, Major prion protein | | 著者 | Swayampakula, M, Baral, P.K, Kav, N.N.V, Aguzzi, A, James, M.N.G. | | 登録日 | 2013-02-14 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody.
Protein Sci., 22, 2013
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4KGJ
 | | Crystal structure of human alpha-L-iduronidase complex with 5-fluoro-alpha-L-idopyranosyluronic acid fluoride | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-fluoro-alpha-L-idopyranosyluronic acid fluoride, ... | | 著者 | Bie, H, Yin, J, He, X, Kermode, A.R, Goddard-Borger, E.D, Withers, S.G, James, M.N.G. | | 登録日 | 2013-04-29 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Insights into mucopolysaccharidosis I from the structure and action of alpha-L-iduronidase.
Nat.Chem.Biol., 9, 2013
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4KH2
 | | Crystal structure of human alpha-L-iduronidase complex with 2-deoxy-2-fluoro-alpha-L-idopyranosyluronic acid fluoride | | 分子名称: | 2,6-anhydro-5-deoxy-5-fluoro-L-idonic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Bie, H, Yin, J, He, X, Kermode, A.R, Goddard-Borger, E.D, Withers, S.G, James, M.N.G. | | 登録日 | 2013-04-29 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Insights into mucopolysaccharidosis I from the structure and action of alpha-L-iduronidase.
Nat.Chem.Biol., 9, 2013
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4KGL
 | | Crystal structure of human alpha-L-iduronidase complex with [2R,3R,4R,5S]-2-carboxy-3,4,5-trihydroxy-piperidine | | 分子名称: | (2R,3R,4R,5S)-3,4,5-trihydroxypiperidine-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Bie, H, Yin, J, He, X, Kermode, A.R, Goddard-Borger, E.D, Withers, S.G, James, M.N.G. | | 登録日 | 2013-04-29 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Insights into mucopolysaccharidosis I from the structure and action of alpha-L-iduronidase.
Nat.Chem.Biol., 9, 2013
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