The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-arginine.

Summary for 3LAJ

Related3bue 2zfz 3cag 3ere 3fhz 3LAP
DescriptorArginine repressor, 5'-D(*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*A)-3', 5'-D(*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*A)-3', ... (5 entities in total)
Functional Keywordsmycobacterium tuberculosis; arginine repressor, dna binding, argr-dna complex, structural genomics, mycobacterium tuberculosis structural proteomics project, xmtb, amino-acid biosynthesis, arginine biosynthesis, cytoplasm, dna-binding, repressor, transcription, transcription regulator
Biological sourceMycobacterium tuberculosis
Cellular locationCytoplasm (Probable) P0A4Y8
Total number of polymer chains12
Total molecular weight134634.28
Cherney, L.T.,Cherney, M.M.,Garen, C.R.,James, M.N.G.,Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) (deposition date: 2010-01-06, release date: 2010-05-05, Last modification date: 2011-07-13)
Primary citation
Cherney, L.T.,Cherney, M.M.,Garen, C.R.,James, M.N.
crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression.
J.Mol.Biol., 399:240-254, 2010
PubMed: 20382162 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2010.03.065
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.202100.7%8.4%4.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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