3LPN

Crystal structure of the phosphoribosylpyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with an ATP analog (AMPCPP).

Summary for 3LPN

Entry DOI	10.2210/pdb3lpn/pdb
Related	1IBS 1U9Y 1U9Z 2H06 2HCR
Descriptor	Ribose-phosphate pyrophosphokinase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, SULFATE ION, ... (4 entities in total)
Functional Keywords	phosphoribosyltransferase, atp analog binding, atp-binding, kinase, metal-binding, nucleotide biosynthesis, nucleotide-binding, transferase
Biological source	Thermoplasma volcanium
Cellular location	Cytoplasm : Q97CA5
Total number of polymer chains	2
Total formula weight	65933.61
Authors	Cherney, M.M.,Cherney, L.T.,Garen, C.R.,James, M.N.G. (deposition date: 2010-02-05, release date: 2011-02-09, Last modification date: 2023-09-06)
Primary citation	Cherney, M.M.,Cherney, L.T.,Garen, C.R.,James, M.N. The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs. J.Mol.Biol., 413:844-856, 2011 Cited by PubMed: 21963988 DOI: 10.1016/j.jmb.2011.09.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation