8C9H
 
 | | AQP7_inhibitor | | 分子名称: | Aquaporin-7, ethyl 4-[(4-pyrazol-1-ylphenyl)methylcarbamoylamino]benzoate | | 著者 | Huang, P, Venskutonyte, R, Gourdon, P, Lindkvist-Petersson, K. | | 登録日 | 2023-01-22 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular basis for human aquaporin inhibition.
Proc.Natl.Acad.Sci.USA, 121, 2024
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5KZV
 | | Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in complex with 20(S)-hydroxycholesterol | | 分子名称: | (3alpha,8alpha)-cholest-5-ene-3,20-diol, Smoothened | | 著者 | Huang, P, Kim, Y, Salic, A. | | 登録日 | 2016-07-25 | | 公開日 | 2016-08-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.616 Å) | | 主引用文献 | Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Cell, 166, 2016
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5KZY
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5KZZ
 | | Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in its apo-form | | 分子名称: | ACETATE ION, GLYCEROL, Smoothened, ... | | 著者 | Huang, P, Kim, Y, Salic, A. | | 登録日 | 2016-07-25 | | 公開日 | 2016-08-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.332 Å) | | 主引用文献 | Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Cell, 166, 2016
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6D35
 | | Crystal structure of Xenopus Smoothened in complex with cholesterol | | 分子名称: | CHOLESTEROL, Smoothened,Soluble cytochrome b562,Smoothened | | 著者 | Huang, P, Zheng, S, Kim, Y, Kruse, A.C, Salic, A. | | 登録日 | 2018-04-14 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structural Basis of Smoothened Activation in Hedgehog Signaling.
Cell, 174, 2018
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6D32
 | | Crystal structure of Xenopus Smoothened in complex with cyclopamine | | 分子名称: | Cyclopamine, Smoothened,Soluble cytochrome b562,Smoothened | | 著者 | Huang, P, Zheng, S, Kim, Y, Kruse, A.C, Salic, A. | | 登録日 | 2018-04-14 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.751 Å) | | 主引用文献 | Structural Basis of Smoothened Activation in Hedgehog Signaling.
Cell, 174, 2018
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7RHR
 | | Cryo-EM structure of Xenopus Patched-1 in nanodisc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Huang, P, Lian, T, Jiang, J, Salic, A. | | 登録日 | 2021-07-18 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex.
Dev.Cell, 57, 2022
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7RHQ
 | | Cryo-EM structure of Xenopus Patched-1 in complex with GAS1 and Sonic Hedgehog | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Huang, P, Lian, T, Wierbowski, B, Garcia-Linares, S, Jiang, J, Salic, A. | | 登録日 | 2021-07-18 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex.
Dev.Cell, 57, 2022
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5K3N
 | | Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with ML209 | | 分子名称: | (3S)-3-(2H-1,3-benzodioxol-5-yl)-1-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-3-(2-hydroxy-4,6-dimethoxyphenyl)propan-1-one, Nuclear receptor ROR-gamma | | 著者 | Huang, P, Rastinejad, F, Lu, J. | | 登録日 | 2016-05-19 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.666 Å) | | 主引用文献 | Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with ML209
To be published
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8AMW
 | | AQP7 dimer of tetramers_C1 | | 分子名称: | Aquaporin-7, GLYCEROL | | 著者 | Huang, P, Venskutonyte, R, Fan, X, Li, P, Yan, N, Gourdon, P, Lindkvist-Petersson, K. | | 登録日 | 2022-08-04 | | 公開日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM structure supports a role of AQP7 as a junction protein.
Nat Commun, 14, 2023
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8AMX
 | | AQP7 dimer of tetramers_D4 | | 分子名称: | Aquaporin-7 | | 著者 | Huang, P, Venskutonyte, R, Fan, X, Li, P, Yan, N, Gourdon, P, Lindkvist-Petersson, K. | | 登録日 | 2022-08-04 | | 公開日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | | 主引用文献 | Cryo-EM structure supports a role of AQP7 as a junction protein.
Nat Commun, 14, 2023
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7VGB
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7VGC
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7Y1S
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7Y1X
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6OMT
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4S14
 | | Crystal structure of the orphan nuclear receptor RORgamma ligand-binding domain in complex with 4alpha-caboxyl, 4beta-methyl-zymosterol (4ACD8) | | 分子名称: | (3beta,4alpha,5beta,14beta)-3-hydroxy-4-methylcholesta-8,24-diene-4-carboxylic acid, Nuclear receptor ROR-gamma, Nuclear receptor-interacting protein 1 | | 著者 | Huang, P, Santori, F.R, Littman, D.R, Rastinejad, F. | | 登録日 | 2015-01-07 | | 公開日 | 2015-02-11 | | 最終更新日 | 2015-02-25 | | 実験手法 | X-RAY DIFFRACTION (3.542 Å) | | 主引用文献 | Identification of Natural ROR gamma Ligands that Regulate the Development of Lymphoid Cells.
Cell Metab, 21, 2015
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4S15
 | | Crystal structure of the orphan nuclear receptor RORalpha ligand-binding domain in complex with 4alpha-caboxyl, 4beta-methyl-zymosterol (4ACD8) | | 分子名称: | (3beta,4alpha,5beta,14beta)-3-hydroxy-4-methylcholesta-8,24-diene-4-carboxylic acid, GLYCEROL, Nuclear receptor ROR-alpha, ... | | 著者 | Huang, P, Santori, F.R, Littman, D.R, Rastinejad, F. | | 登録日 | 2015-01-08 | | 公開日 | 2015-02-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | | 主引用文献 | Identification of Natural ROR gamma Ligands that Regulate the Development of Lymphoid Cells.
Cell Metab, 21, 2015
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4UOT
 | | Thermodynamic hyperstability in parametrically designed helical bundles | | 分子名称: | DESIGNED HELICAL BUNDLE 5H2L | | 著者 | Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D. | | 登録日 | 2014-06-09 | | 公開日 | 2014-11-05 | | 最終更新日 | 2014-11-19 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | High Thermodynamic Stability of Parametrically Designed Helical Bundles
Science, 346, 2014
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4UOS
 | | Thermodynamic hyperstability in parametrically designed helical bundles | | 分子名称: | DESIGNED HELICAL BUNDLE | | 著者 | Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D. | | 登録日 | 2014-06-09 | | 公開日 | 2014-11-05 | | 最終更新日 | 2016-12-14 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | High Thermodynamic Stability of Parametrically Designed Helical Bundles
Science, 346, 2014
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5WUG
 | | Expression, characterization and crystal structure of a novel beta-glucosidase from Paenibacillus barengoltzii | | 分子名称: | Beta-glucosidase | | 著者 | Jiang, Z, Wu, S, Yang, D, Qin, Z, You, X, Huang, P. | | 登録日 | 2016-12-17 | | 公開日 | 2018-01-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.216 Å) | | 主引用文献 | Expression, Biochemical Characterization and Structure Resolution of beta-glucosidase from Paenibacillus barengoltzii
J Food Sci Technol(China), 2019
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6JFX
 | | Crystal structure of Pullulanase from Paenibacillus barengoltzii complex with maltopentaose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Wu, S.W, Yang, S.Q, Qin, Z, You, X, Huang, P, Jiang, Z.Q. | | 登録日 | 2019-02-12 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | | 主引用文献 | Structural basis of carbohydrate binding in domain C of a type I pullulanase from Paenibacillus barengoltzii.
Acta Crystallogr D Struct Biol, 76, 2020
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6JHF
 | | Crystal structure of apo Pullulanase from Paenibacillus barengoltzii | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Wu, S.W, Yang, S.Q, Qin, Z, You, X, Huang, P, Jiang, Z.Q. | | 登録日 | 2019-02-18 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Structural basis of carbohydrate binding in domain C of a type I pullulanase from Paenibacillus barengoltzii.
Acta Crystallogr D Struct Biol, 76, 2020
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6JEQ
 | | Crystal structure of Pullulanase from Paenibacillus barengoltzii complex with beta-cyclodextrin | | 分子名称: | CALCIUM ION, CHLORIDE ION, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), ... | | 著者 | Wu, S.W, Yang, S.Q, Qin, Z, You, X, Huang, P, Jiang, Z.Q. | | 登録日 | 2019-02-07 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Structural basis of carbohydrate binding in domain C of a type I pullulanase from Paenibacillus barengoltzii.
Acta Crystallogr D Struct Biol, 76, 2020
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6JFJ
 | | Crystal structure of Pullulanase from Paenibacillus barengoltzii complex with maltohexaose and alpha-cyclodextrin | | 分子名称: | CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Wu, S.W, Yang, S.Q, Qin, Z, You, X, Huang, P, Jiang, Z.Q. | | 登録日 | 2019-02-09 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.932 Å) | | 主引用文献 | Structural basis of carbohydrate binding in domain C of a type I pullulanase from Paenibacillus barengoltzii.
Acta Crystallogr D Struct Biol, 76, 2020
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