7VGC

Crystal structure of prolyl oligopeptidase from Microbulbifer arenaceous complex with a transition state analog inhibitor ZPR

Summary for 7VGC

Entry DOI	10.2210/pdb7vgc/pdb
Related	7VGB
Related PRD ID	PRD_000692
Descriptor	prolyl oligopeptidase, N-BENZYLOXYCARBONYL-L-PROLYL-L-PROLINAL, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	s9a, prolyl endopeptidase, serine protease, mental disorder, amnesia, hydrolase
Biological source	Microbulbifer arenaceous
Total number of polymer chains	1
Total formula weight	80353.46
Authors	Huang, P.,Yang, S.Q.,Jiang, Z.Q. (deposition date: 2021-09-15, release date: 2022-05-25, Last modification date: 2023-11-29)
Primary citation	Huang, P.,Lv, A.,Yan, Q.,Jiang, Z.,Yang, S. The structure and molecular dynamics of prolyl oligopeptidase from Microbulbifer arenaceous provide insights into catalytic and regulatory mechanisms. Acta Crystallogr D Struct Biol, 78:735-751, 2022 Cited by PubMed: 35647921 DOI: 10.1107/S2059798322004247 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.722 Å)

Structure validation