8C9H
AQP7_inhibitor
Summary for 8C9H
| Entry DOI | 10.2210/pdb8c9h/pdb |
| EMDB information | 15528 16510 |
| Descriptor | Aquaporin-7, ethyl 4-[(4-pyrazol-1-ylphenyl)methylcarbamoylamino]benzoate (2 entities in total) |
| Functional Keywords | aquaglyceroporin, glycerol channel, dimer of tetramers, inhibitor, membrane protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 8 |
| Total formula weight | 301030.34 |
| Authors | Huang, P.,Venskutonyte, R.,Gourdon, P.,Lindkvist-Petersson, K. (deposition date: 2023-01-22, release date: 2024-01-31, Last modification date: 2024-03-06) |
| Primary citation | Huang, P.,Abacka, H.,Wilson, C.J.,Wind, M.L.,Rutzler, M.,Hagstrom-Andersson, A.,Gourdon, P.,de Groot, B.L.,Venskutonyte, R.,Lindkvist-Petersson, K. Molecular basis for human aquaporin inhibition. Proc.Natl.Acad.Sci.USA, 121:e2319682121-e2319682121, 2024 Cited by PubMed: 38319972DOI: 10.1073/pnas.2319682121 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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