Search by PDB author

Structure of BACE in complex with (S)-4-(3-chloro-5-(5-(prop-1-yn-1-yl)pyridin-3-yl)thiophen-2-yl)-1,4-dimethyl-6-oxotetrahydropyrimidin-2(1H)-iminium
Descriptor:	(2Z,6S)-6-{3-chloro-5-[5-(prop-1-yn-1-yl)pyridin-3-yl]thiophen-2-yl}-2-imino-3,6-dimethyltetrahydropyrimidin-4(1H)-one, Beta-secretase 1
Authors:	Orth, P.
Deposit date:	2012-06-26
Release date:	2012-08-08
Last modified:	2013-06-19
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor That Affords Robust CNS A(beta) Reduction ACS Med Chem Lett, 3, 2012

3K9X

X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE
Descriptor:	CALCIUM ION, GLYCEROL, N-{N'-(2-methyl-1-benzofuran-5-yl)-N-[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]carbamimidoyl}pyridine-3-carboxamide, ...
Authors:	Klei, H.E, Kish, K, Ghosh, K, Rushith, A.
Deposit date:	2009-10-16
Release date:	2009-12-15
Last modified:	2017-11-01
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577 Bioorg.Med.Chem.Lett., 19, 2009

3S41

Glucokinase in complex with activator and glucose
Descriptor:	Glucokinase, N,N-dimethyl-5-({2-methyl-6-[(5-methylpyrazin-2-yl)carbamoyl]-1-benzofuran-4-yl}oxy)pyrimidine-2-carboxamide, SODIUM ION, ...
Authors:	Liu, S.
Deposit date:	2011-05-18
Release date:	2011-09-14
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.18 Å)
Cite:	Designing glucokinase activators with reduced hypoglycemia risk: discovery of N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzofuran-4-yloxy)pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus MEDCHEMCOMM, 2, 2011

2OK3

X-ray structure of human cyclophilin J at 2.0 angstrom
Descriptor:	NICKEL (II) ION, Peptidyl-prolyl cis-trans isomerase-like 3
Authors:	Xia, Z.
Deposit date:	2007-01-15
Release date:	2008-01-22
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Targeting Cyclophilin J, a novel peptidyl-prolyl isomerase, can induce cellular G1/S arrest and repress the growth of Hepatocellular carcinoma To be Published

1YT5

Crystal structure of NAD kinase from Thermotoga maritima
Descriptor:	SULFATE ION, inorganic polyphosphate/ATP-NAD kinase
Authors:	Berkeley Structural Genomics Center (BSGC)
Deposit date:	2005-02-09
Release date:	2005-04-05
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structure of a NAD kinase from Thermotoga maritima at 2.3 A resolution. Acta Crystallogr.,Sect.F, 61, 2005

5XYF

Crystal structure of the human TIN2-TPP1-TRF2 telomeric complex
Descriptor:	Adrenocortical dysplasia protein homolog, TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2
Authors:	Hu, C, Chen, Y.
Deposit date:	2017-07-07
Release date:	2017-12-13
Method:	X-RAY DIFFRACTION (2.202 Å)
Cite:	Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex. Cell Res., 27, 2017

8D0O

Human alpha1,3-fucosyltransferase FUT9, heavy atom derivative
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, CESIUM ION, ...
Authors:	Kadirvelraj, R, Wood, Z.A.
Deposit date:	2022-05-26
Release date:	2023-05-24
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19, 2023

8D0R

Human FUT9 bound to GDP and H-Type 2
Descriptor:	1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:	Kadirvelraj, R, Wood, Z.A.
Deposit date:	2022-05-26
Release date:	2023-05-24
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.4 Å)
Cite:	Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19, 2023

8D0W

Human FUT9 bound to H-Type 2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GLYCEROL, ...
Authors:	Kadirvelraj, R, Wood, Z.A.
Deposit date:	2022-05-26
Release date:	2023-05-24
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.332 Å)
Cite:	Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19, 2023

8D0U

Human FUT9 bound to GDP
Descriptor:	1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:	Kadirvelraj, R, Wood, Z.A.
Deposit date:	2022-05-26
Release date:	2023-05-24
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.29 Å)
Cite:	Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19, 2023

8D0X

Human FUT9 bound to LNnT
Descriptor:	1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GLYCEROL, ...
Authors:	Kadirvelraj, R, Wood, Z.A.
Deposit date:	2022-05-26
Release date:	2023-05-24
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.33 Å)
Cite:	Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19, 2023

8D0P

Human FUT9, unliganded
Descriptor:	1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, SULFATE ION, ...
Authors:	Kadirvelraj, R, Wood, Z.A.
Deposit date:	2022-05-26
Release date:	2023-05-24
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.09 Å)
Cite:	Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19, 2023

8D0S

Human FUT9 bound to GDP and LNnT
Descriptor:	1,2-ETHANEDIOL, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:	Kadirvelraj, R, Wood, Z.A.
Deposit date:	2022-05-26
Release date:	2023-05-24
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.37 Å)
Cite:	Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19, 2023

8D0Q

Human FUT9 bound to GDP-CF3-Fucose and H-Type 2
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:	Kadirvelraj, R, Wood, Z.A.
Deposit date:	2022-05-26
Release date:	2023-05-31
Last modified:	2023-10-25
Method:	X-RAY DIFFRACTION (1.39 Å)
Cite:	Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19, 2023

1H4N

H94N CARBONIC ANHYDRASE II COMPLEXED WITH TRIS
Descriptor:	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CARBONIC ANHYDRASE II, ZINC ION
Authors:	Lesburg, C.A, Christianson, D.W.
Deposit date:	1997-05-29
Release date:	1997-09-17
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity. Biochemistry, 36, 1997

1T6S

Crystal structure of a conserved hypothetical protein from Chlorobium tepidum
Descriptor:	NITRATE ION, conserved hypothetical protein
Authors:	Kim, J.S, Shin, D.H, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:	2004-05-07
Release date:	2004-12-07
Last modified:	2024-02-14
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning. Proteins, 62, 2006

7MFH

Crystal structure of BIO-32546 bound mouse Autotaxin
Descriptor:	(1R,3S,5S)-8-{(1S)-1-[8-(trifluoromethyl)-7-{[(1s,4R)-4-(trifluoromethyl)cyclohexyl]oxy}naphthalen-2-yl]ethyl}-8-azabicyclo[3.2.1]octane-3-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Chodaparambil, J.V.
Deposit date:	2021-04-09
Release date:	2022-04-13
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Discovery of Potent Selective Nonzinc Binding Autotaxin Inhibitor BIO-32546. Acs Med.Chem.Lett., 12, 2021

1H9Q

H119Q CARBONIC ANHYDRASE II
Descriptor:	CARBONIC ANHYDRASE II, ZINC ION
Authors:	Lesburg, C.A, Christianson, D.W.
Deposit date:	1997-05-29
Release date:	1997-09-17
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity. Biochemistry, 36, 1997

1H9N

H119N CARBONIC ANHYDRASE II
Descriptor:	CARBONIC ANHYDRASE II, ZINC ION
Authors:	Lesburg, C.A, Christianson, D.W.
Deposit date:	1997-05-29
Release date:	1997-09-17
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity. Biochemistry, 36, 1997

7QZ8

Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp
Descriptor:	DAUNOMYCIN, Transcriptional regulator, PadR-like family
Authors:	Thunnissen, A.M.W.H.
Deposit date:	2022-01-30
Release date:	2022-11-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022

7QZ5

Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5-fluoroTrp
Descriptor:	Transcriptional regulator, PadR-like family
Authors:	Thunnissen, A.M.W.H.
Deposit date:	2022-01-30
Release date:	2022-11-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022

7QZ9

Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp
Descriptor:	Transcriptional regulator, PadR-like family
Authors:	Thunnissen, A.M.W.H.
Deposit date:	2022-01-30
Release date:	2022-11-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.31 Å)
Cite:	The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022

7QZ7

Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5,6,7-trifluoroTrp
Descriptor:	DAUNOMYCIN, Transcriptional regulator, PadR-like family
Authors:	Thunnissen, A.M.W.H.
Deposit date:	2022-01-30
Release date:	2022-11-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022

7QZ6

Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5-fluoroTrp
Descriptor:	DAUNOMYCIN, Transcriptional regulator, PadR-like family
Authors:	Thunnissen, A.M.W.H.
Deposit date:	2022-01-30
Release date:	2022-11-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.15 Å)
Cite:	The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022

7CI3

The crystal structure of the SARS-CoV-2 ORF7a ectodomain
Descriptor:	Orf7a protein
Authors:	Zhou, Z, Zhou, Z, Chen, S.
Deposit date:	2020-07-07
Release date:	2021-03-03
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14 + monocytes. Iscience, 24, 2021

<1 2 3 456 7 8 >

Total results:	178
Displayed results:	25
Sorted by:	Hit score (from highest)