1T6S

Crystal structure of a conserved hypothetical protein from Chlorobium tepidum

Summary for 1T6S

• Entry DOI: 10.2210/pdb1t6s/pdb
• Descriptor: conserved hypothetical protein, NITRATE ION (3 entities in total)
• Functional Keywords: a winged helix-turn-helix, structural genomics, bsgc structure funded by nih, protein structure initiative, psi, berkeley structural genomics center, unknown function
• Biological source: Chlorobium tepidum TLS
• Cellular location: Cytoplasm (By similarity): Q8KF54
• Total number of polymer chains: 2
• Total formula weight: 38256.07

Authors

Kim, J.S.,Shin, D.H.,Kim, R.,Kim, S.H.,Berkeley Structural Genomics Center (BSGC) (deposition date: 2004-05-07, release date: 2004-12-07, Last modification date: 2024-02-14)

Primary citation

Kim, J.S.,Shin, D.H.,Pufan, R.,Huang, C.,Yokota, H.,Kim, R.,Kim, S.H.
Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning.
Proteins, 62:322-328, 2006

PubMed Abstract: Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins.

PubMed: 16294331
DOI: 10.1002/prot.20751

Experimental method

X-RAY DIFFRACTION (1.95 Å)