5JDK
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3MGE
| X-ray Structure of Hexameric HIV-1 CA | Descriptor: | 1,2-ETHANEDIOL, Capsid protein p24 | Authors: | Pornillos, O. | Deposit date: | 2010-04-05 | Release date: | 2010-07-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Disulfide Bond Stabilization of the Hexameric Capsomer of Human Immunodeficiency Virus. J.Mol.Biol., 401, 2010
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5CD3
| Structure of immature VRC01-class antibody DRVIA7 | Descriptor: | DRVIA7 Heavy Chain, DRVIA7 Light Chain | Authors: | Kong, L, Wilson, I.A. | Deposit date: | 2015-07-02 | Release date: | 2016-04-06 | Last modified: | 2018-09-05 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity, 44, 2016
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5CD5
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3H47
| X-ray Structure of Hexameric HIV-1 CA | Descriptor: | Capsid protein p24 | Authors: | Pornillos, O. | Deposit date: | 2009-04-18 | Release date: | 2009-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray structures of the hexameric building block of the HIV capsid. Cell(Cambridge,Mass.), 137, 2009
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3GV2
| X-ray Structure of Hexameric HIV-1 CA | Descriptor: | Capsid protein p24,Carbon dioxide-concentrating mechanism protein CcmK homolog 4 | Authors: | Kelly, B.N. | Deposit date: | 2009-03-30 | Release date: | 2009-06-23 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (7 Å) | Cite: | X-ray structures of the hexameric building block of the HIV capsid. Cell(Cambridge,Mass.), 137, 2009
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7XHJ
| Crystal structure of RuvC from Deinococcus radiodurans | Descriptor: | Crossover junction endodeoxyribonuclease RuvC | Authors: | Qin, C, Zhao, Y. | Deposit date: | 2022-04-08 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and Functional Characterization of the Holliday Junction Resolvase RuvC from Deinococcus radiodurans. Microorganisms, 10, 2022
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3H4E
| X-ray Structure of Hexameric HIV-1 CA | Descriptor: | Capsid protein p24 | Authors: | Pornillos, O. | Deposit date: | 2009-04-19 | Release date: | 2009-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.704 Å) | Cite: | X-ray structures of the hexameric building block of the HIV capsid. Cell(Cambridge,Mass.), 137, 2009
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7U2E
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody ADI-55688 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-55688 heavy chain, ADI-55688 light chain, ... | Authors: | Yuan, M, Zhu, X, Wilson, I.A. | Deposit date: | 2022-02-23 | Release date: | 2022-05-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | A broad and potent neutralization epitope in SARS-related coronaviruses. Proc.Natl.Acad.Sci.USA, 119, 2022
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7U2D
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody ADG20 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADG20 heavy chain, ADG20 light chain, ... | Authors: | Zhu, X, Yuan, M, Wilson, I.A. | Deposit date: | 2022-02-23 | Release date: | 2022-05-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | A broad and potent neutralization epitope in SARS-related coronaviruses. Proc.Natl.Acad.Sci.USA, 119, 2022
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8H6P
| Complex structure of CDK2/Cyclin E1 and a potent, selective macrocyclic inhibitor | Descriptor: | (7S,10R)-11-oxa-2,4,5,13,17,23-hexaazatetracyclo[17.3.1.1~3,6~.1~7,10~]pentacosa-1(23),3(25),5,19,21-pentaene-12,18-dione, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 | Authors: | Ren, X. | Deposit date: | 2022-10-18 | Release date: | 2023-02-22 | Last modified: | 2023-03-29 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design. Acs Med.Chem.Lett., 14, 2023
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8H6T
| Complex structure of CDK2/Cyclin E1 and a potent, selective small molecule inhibitor | Descriptor: | (1R,3S)-3-{3-[(pyridin-2-yl)amino]-1H-pyrazol-5-yl}cyclopentyl propan-2-ylcarbamate, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 | Authors: | Ren, X. | Deposit date: | 2022-10-18 | Release date: | 2023-02-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design. Acs Med.Chem.Lett., 14, 2023
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5B7J
| Structure model of Sap1-DNA complex | Descriptor: | DNA (5'-D(*AP*AP*TP*AP*TP*TP*GP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*AP*TP*AP*TP*T)-3'), Switch-activating protein 1 | Authors: | Jin, C, Hu, Y, Ding, J, Zhang, Y. | Deposit date: | 2016-06-07 | Release date: | 2017-02-22 | Last modified: | 2017-05-24 | Method: | SOLUTION NMR | Cite: | Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe J. Biol. Chem., 292, 2017
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4JM2
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4JM4
| Crystal Structure of PGT 135 Fab | Descriptor: | PGT 135 Heavy Chain, PGT 135 Light Chain | Authors: | Kong, L, Wilson, I.A. | Deposit date: | 2013-03-13 | Release date: | 2013-05-29 | Last modified: | 2013-07-17 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat.Struct.Mol.Biol., 20, 2013
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7COC
| Ternary complex of DNA polymerase Mu (K438A/Q441A) with 1-nt gapped DNA (T:dGMPNPP) | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... | Authors: | Guo, M, Zhao, Y. | Deposit date: | 2020-08-04 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
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7COB
| Ternary complex of DNA polymerase Mu (Q441A) with 1-nt gapped DNA (T:dGMPNPP) | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... | Authors: | Guo, M, Zhao, Y. | Deposit date: | 2020-08-04 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.797 Å) | Cite: | Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
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7CO6
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7CO9
| Ternary complex of DNA polymerase Mu with 1-nt gapped DNA (T:dGMPNPP) and Mg | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... | Authors: | Guo, M, Zhao, Y. | Deposit date: | 2020-08-04 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.599 Å) | Cite: | Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
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7CO8
| Ternary complex of DNA polymerase Mu with 2-nt gapped DNA (T:dGMPNPP) | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... | Authors: | Guo, M, Zhao, Y. | Deposit date: | 2020-08-04 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.697 Å) | Cite: | Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
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7COA
| Ternary complex of DNA polymerase Mu with 1-nt gapped DNA (T:dGMPNPP) and Mn | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... | Authors: | Guo, M, Zhao, Y. | Deposit date: | 2020-08-04 | Release date: | 2021-06-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12, 2021
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7COD
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6WO4
| Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody HC11 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | Authors: | Tzarum, N, Wilson, I.A, Law, M. | Deposit date: | 2020-04-24 | Release date: | 2020-08-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.349 Å) | Cite: | An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Sci Adv, 6, 2020
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6WO3
| Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody U1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | Authors: | Tzarum, N, Wilson, I.A, Law, M. | Deposit date: | 2020-04-24 | Release date: | 2020-08-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.382 Å) | Cite: | An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Sci Adv, 6, 2020
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6WOQ
| Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... | Authors: | Tzarum, N, Wilson, I.A, Law, M. | Deposit date: | 2020-04-25 | Release date: | 2020-08-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.667 Å) | Cite: | An alternate conformation of HCV E2 neutralizing face as an additional vaccine target. Sci Adv, 6, 2020
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