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6VGD
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BU of 6vgd by Molmil
Crystal structure of the DNA binding domain (DBD) of human FLI1 and the complex of the DBD of human Runx2 with core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC
Descriptor: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2020-01-07
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.
Structure, 29, 2021
8CT0
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BU of 8ct0 by Molmil
Crystal structure of FAD reductase CtcQ from Kitasatospora aureofaciens in complex with FAD and NAD
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Flavin reductase (NADH), ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2022-05-13
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures and complex formation of halogenase CtcP and FAD reductase CtcQ from the chlortetracycline biosynthetic pathway
To Be Published
6DY5
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BU of 6dy5 by Molmil
Crystal structure of double-stranded DNA AGGGATCCCT in complex with Zn2+
Descriptor: DNA (5'-D(*AP*GP*GP*GP*AP*TP*CP*CP*CP*T)-3'), SPERMIDINE, ZINC ION
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2018-07-01
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Utilizing guanine coordinated Zn2+ to determine DNA crystal structures by single-wavelength anomalous diffraction
Acta Crystallogr.,Sect.D, 75, 2019
6DWT
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BU of 6dwt by Molmil
Crystal structure of double-stranded DNA GAGGCCTC, crystals grown in Mg2+
Descriptor: DNA (5'-D(*GP*AP*GP*GP*CP*CP*TP*C)-3'), MAGNESIUM ION
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2018-06-27
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Utilizing guanine coordinated Zn2+ to determine DNA crystal structures by single-wavelength anomalous diffraction
Acta Crystallogr.,Sect.D, 75, 2019
6DY9
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BU of 6dy9 by Molmil
Crystal structure of double-stranded DNA GGGATCCC; crystals grown in Zn2+
Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*CP*CP*C)-3'), ZINC ION
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2018-07-01
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Utilizing guanine coordinated Zn2+ to determine DNA crystal structures by single-wavelength anomalous diffraction
Acta Crystallogr.,Sect.D, 75, 2019
6DXJ
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BU of 6dxj by Molmil
Crystal structure of double-stranded DNA GAGGCCTC; crystals grown in Zn2+
Descriptor: DNA (5'-D(*GP*AP*GP*GP*CP*CP*TP*C)-3'), ZINC ION
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2018-06-29
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Utilizing guanine coordinated Zn2+ to determine DNA crystal structures by single-wavelength anomalous diffraction
Acta Crystallogr.,Sect.D, 75, 2019
6VG2
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BU of 6vg2 by Molmil
Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with 16-mer DNA CAGAGGATGTGGCTTC
Descriptor: DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*GP*CP*TP*TP*C)-3'), Friend leukemia integration 1 transcription factor
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2020-01-07
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.
Structure, 29, 2021
6VGG
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BU of 6vgg by Molmil
Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC
Descriptor: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ...
Authors:Hou, C, Rohr, J, Tsodikov, O.V.
Deposit date:2020-01-08
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.31 Å)
Cite:Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.
Structure, 29, 2021
6VGE
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BU of 6vge by Molmil
Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC
Descriptor: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2020-01-07
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.25 Å)
Cite:Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.
Structure, 29, 2021
6VG8
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BU of 6vg8 by Molmil
Crystal structure of the DNA binding domains of human FLI1 and Runx2 in complex with 16-mer DNA CAGAGGATGTGGCTTC
Descriptor: DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), Friend leukemia integration 1 transcription factor, ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2020-01-07
Release date:2020-11-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.31 Å)
Cite:Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.
Structure, 29, 2021
9MX9
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BU of 9mx9 by Molmil
Crystal structure of the DNA binding domain of FLI1 (F362A) in complex with a DNA containing two contiguous GGAA sites
Descriptor: CALCIUM ION, DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*GP*AP*AP*GP*TP*G)-3'), ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2025-01-17
Release date:2025-03-12
Last modified:2025-04-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure and cooperative formation of a FLI1 filament on contiguous GGAA DNA sites.
Nucleic Acids Res., 53, 2025
9MWY
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BU of 9mwy by Molmil
Crystal structure of the DNA binding domain of FLI1 in complex with a DNA containing four contiguous GGAA sites
Descriptor: 25-mer DNA containing four contiguous GGAA sites, bottom strand, top strand, ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2025-01-17
Release date:2025-03-12
Last modified:2025-04-23
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Structure and cooperative formation of a FLI1 filament on contiguous GGAA DNA sites.
Nucleic Acids Res., 53, 2025
9MX8
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BU of 9mx8 by Molmil
Crystal structure of the DNA binding domain of FLI1 in complex with a DNA containing three contiguous GGAA sites
Descriptor: DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*TP*TP*CP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(P*GP*AP*CP*CP*GP*GP*AP*AP*GP*GP*AP*AP*GP*GP*AP*AP*GP*TP*G)-3'), Friend leukemia integration 1 transcription factor
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2025-01-17
Release date:2025-03-12
Last modified:2025-04-23
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structure and cooperative formation of a FLI1 filament on contiguous GGAA DNA sites.
Nucleic Acids Res., 53, 2025
9MXA
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BU of 9mxa by Molmil
Crystal structure of the DNA binding domain of FLI1 (wild-type) in complex with a DNA containing two contiguous GGAA sites
Descriptor: DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*GP*AP*AP*GP*TP*G)-3'), Friend leukemia integration 1 transcription factor
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2025-01-17
Release date:2025-03-12
Last modified:2025-04-23
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure and cooperative formation of a FLI1 filament on contiguous GGAA DNA sites.
Nucleic Acids Res., 53, 2025
9MP1
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BU of 9mp1 by Molmil
Crystal structure of mithramycin analogue MTM SA-7-methyl-Trp in complex with double-stranded DNA AGAGGCCTCT
Descriptor: DNA (5'-D(*AP*GP*AP*GP*GP*CP*CP*TP*CP*T)-3'), SODIUM ION, ZINC ION, ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2024-12-29
Release date:2025-04-30
Last modified:2025-05-14
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:The Position of Indole Methylation Controls the Structure, DNA Binding, and Cellular Functions of Mithramycin SA-Trp Analogues.
Chembiochem, 2025
9MOZ
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BU of 9moz by Molmil
Crystal structure of mithramycin analogue MTM SA-5-methyl-Trp in complex with DNA AGAGGCCTCT
Descriptor: CHLORIDE ION, DNA (5'-D(*AP*GP*AP*GP*GP*CP*CP*TP*CP*T)-3'), SODIUM ION, ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2024-12-28
Release date:2025-04-30
Last modified:2025-05-14
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The Position of Indole Methylation Controls the Structure, DNA Binding, and Cellular Functions of Mithramycin SA-Trp Analogues.
Chembiochem, 2025
7JSL
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BU of 7jsl by Molmil
Crystal structure of the DNA binding domain of human transcription factor ERF in the oxidized form, in complex with double-stranded DNA ACCGGAAGTG
Descriptor: DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ETS domain-containing transcription factor ERF
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2020-08-14
Release date:2020-11-25
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (4.51 Å)
Cite:Structural Insight into the DNA Binding Function of Transcription Factor ERF.
Biochemistry, 2020
7JSA
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BU of 7jsa by Molmil
Crystal structure of the DNA binding domain of human transcription factor ERF in the reduced form, in complex with double-stranded DNA ACCGGAAGTG
Descriptor: DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ETS domain-containing transcription factor ERF
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2020-08-14
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Insight into the DNA Binding Function of Transcription Factor ERF.
Biochemistry, 2020
9CP6
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BU of 9cp6 by Molmil
Crystal structure of the DNA binding domain of FLI1 (residues 259-371)
Descriptor: Friend leukemia integration 1 transcription factor, SODIUM ION
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2024-07-17
Release date:2025-03-12
Last modified:2025-04-09
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure and cooperative formation of a FLI1 filament on contiguous GGAA DNA sites.
Nucleic Acids Res., 53, 2025
5JVT
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BU of 5jvt by Molmil
Crystal structure of the DNA binding domain of transcription factor FLI1 in complex with an 11-mer DNA GACCGGAAGTG
Descriptor: DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), Friend leukemia integration 1 transcription factor, ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2016-05-11
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
5JVW
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BU of 5jvw by Molmil
Crystal structure of mithramycin analogue MTM SA-Trp in complex with a 10-mer DNA AGAGGCCTCT.
Descriptor: DNA (5'-D(*AP*GP*AP*GP*GP*CP*CP*TP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Trp, ...
Authors:Hou, C, Rohr, J, Tsodikov, O.V.
Deposit date:2016-05-11
Release date:2016-09-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
5JW0
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BU of 5jw0 by Molmil
Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGTACCCT
Descriptor: DNA (5'-D(P*AP*GP*GP*GP*TP*AP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ...
Authors:Hou, C, Rohr, J, Tsodikov, O.V.
Deposit date:2016-05-11
Release date:2016-09-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
5JW2
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BU of 5jw2 by Molmil
Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGATCCCT
Descriptor: DNA (5'-D(*AP*GP*GP*GP*AP*TP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ...
Authors:Hou, C, Rohr, J, Tsodikov, O.V.
Deposit date:2016-05-11
Release date:2016-09-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1.
Nucleic Acids Res., 44, 2016
7V0B
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BU of 7v0b by Molmil
Crystal structure of halogenase CtcP from Kitasatospora aureofaciens in complex with FAD
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2022-05-10
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structures and complex formation of halogenase CtcP and FAD reductase CtcQ from the chlortetracycline biosynthetic pathway
To Be Published
7V0D
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BU of 7v0d by Molmil
Crystal structure of halogenase CtcP from Kitasatospora aureofaciens
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2022-05-10
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures and complex formation of halogenase CtcP and FAD reductase CtcQ from the chlortetracycline biosynthetic pathway
To Be Published

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PDB entries from 2025-05-14

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