6Q6R
 
 | | Recognition of different base tetrads by RHAU: X-ray crystal structure of G4 recognition motif bound to the 3-end tetrad of a DNA G-quadruplex | | 分子名称: | ATP-dependent DNA/RNA helicase DHX36, POTASSIUM ION, Parallel stranded DNA G-quadruplex | | 著者 | Heddi, B, Cheong, V.V, Schmitt, E, Mechulam, Y, Phan, A.T. | | 登録日 | 2018-12-11 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex.
J.Struct.Biol., 209, 2020
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2LD8
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2N16
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2N21
 | | Solution structure of complex between DNA G-quadruplex and G-quadruplex recognition domain of RHAU | | 分子名称: | ATP-dependent RNA helicase DHX36, DNA (5'-D(*TP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') | | 著者 | Heddi, B, Cheong, V.V, Martadinata, H, Phan, A.T. | | 登録日 | 2015-04-25 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide-quadruplex complex.
Proc.Natl.Acad.Sci.USA, 112, 2015
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2N60
 | | G-quadruplexes with (4n-1) guanines in the G-tetrad core: formation of a G-triad water complex and implication for small-molecule binding | | 分子名称: | DNA (5'-D(*TP*TP*GP*TP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') | | 著者 | Heddi, B, Martin-Pintado, N, Serimbetov, Z, Kari, T.M, Phan, A.T. | | 登録日 | 2015-08-08 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | G-quadruplexes with (4n - 1) guanines in the G-tetrad core: formation of a G-triadwater complex and implication for small-molecule binding
Nucleic Acids Res., 44, 2016
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6FQ2
 | | Structure of minimal sequence for left -handed G-quadruplex formation | | 分子名称: | DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION | | 著者 | Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B. | | 登録日 | 2018-02-13 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew. Chem. Int. Ed. Engl., 58, 2019
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6K3X
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6GZ6
 | | Structure of a left-handed G-quadruplex | | 分子名称: | DNA (27-MER), POTASSIUM ION | | 著者 | Bakalar, B, Heddi, B, Schmitt, E, Mechulam, Y, Phan, A.T. | | 登録日 | 2018-07-03 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | | 主引用文献 | A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew.Chem.Int.Ed.Engl., 58, 2019
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6H1K
 | | The major G-quadruplex form of HIV-1 LTR | | 分子名称: | DNA (28-MER) | | 著者 | Phan, A.T, Heddi, B, Butovskaya, E, Bakalar, B, Richter, S.N. | | 登録日 | 2018-07-11 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop.
J. Am. Chem. Soc., 140, 2018
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6K3Y
 | | G-quadruplex complex with cyclic dinucleotide 3'-3' cGAMP | | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, DNA (5'-D(*TP*TP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') | | 著者 | Winnerdy, F.R, Heddi, B, Phan, A.T. | | 登録日 | 2019-05-22 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structures of a G-Quadruplex Bound to Linear- and Cyclic-Dinucleotides.
J.Am.Chem.Soc., 141, 2019
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2N4Y
 | | Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome | | 分子名称: | DNA_(5'-D(*CP*TP*GP*GP*GP*CP*GP*GP*GP*AP*CP*TP*GP*GP*GP*GP*AP*GP*TP*GP*GP*T)-3') | | 著者 | DeNicola, B, Lech, C.J, Heddi, B, Regmi, S, Frasson, I, Perrone, R, Richter, S.N, Phan, A.T. | | 登録日 | 2015-07-02 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome.
Nucleic Acids Res., 44, 2016
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2LE6
 | | Structure of a dimeric all-parallel-stranded G-quadruplex stacked via the 5'-to-5' interface | | 分子名称: | DNA (5'-D(*GP*IP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') | | 著者 | Do, N.Q, Lim, K.W, Teo, M.H, Heddi, B, Phan, A.T. | | 登録日 | 2011-06-10 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activity
Nucleic Acids Res., 2011
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2MB2
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2MAY
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2MB3
 | | Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative | | 分子名称: | (12S,27S)-12,27-bis(4-aminobutyl)-4,30-dimethyl-3,7,14,18,22,29-hexaoxa-11,26,31,32,33,34,35,36-octaazaheptacyclo[26.2. 1.1~2,5~.1~6,9~.1~13,16~.1~17,20~.1~21,24~]hexatriaconta-1(30),2(36),4,6(35),8,13(34),15,17(33),19,21(32),23,28(31)-dode caene-10,25-dione, DNA_(5'-D(*TP*TP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*A)-3') | | 著者 | Chung, W.J, Heddi, B, Tera, M, Iida, K, Nagasawa, K, Phan, A.T. | | 登録日 | 2013-07-24 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of an intramolecular (3 + 1) human telomeric g-quadruplex bound to a telomestatin derivative.
J.Am.Chem.Soc., 135, 2013
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2MB4
 | | Solution structure of a stacked dimeric G-quadruplex formed by a segment of the human CEB1 minisatellite | | 分子名称: | DNA_(5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*TP*GP*G)-3') | | 著者 | Adrian, M, Ang, D.J, Lech, C, Heddi, B, Nicolas, A, Phan, A.T. | | 登録日 | 2013-07-25 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Conformational Dynamics of a Stacked Dimeric G-Quadruplex Formed by the Human CEB1 Minisatellite.
J.Am.Chem.Soc., 136, 2014
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2MBJ
 | | Structure of an antiparallel (2+2) G-quadruplex formed by human telomeric repeats in Na+ solution (with G22-to-BrG substitution) | | 分子名称: | DNA_(27-MER) | | 著者 | Lim, K.W, Ng, V.C.M, Martin-Pintado, N, Heddi, B, Phan, A.T. | | 登録日 | 2013-08-02 | | 公開日 | 2013-09-18 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the human telomere in Na+ solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity.
Nucleic Acids Res., 41, 2013
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2MGN
 | | Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC3 | | 分子名称: | 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3', N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide | | 著者 | Chung, W.J, Heddi, B, Hamon, F, Teulade-Fichou, M.P, Phan, A.T. | | 登録日 | 2013-11-01 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of a G-quadruplex Bound to the Bisquinolinium Compound Phen-DC3.
Angew.Chem.Int.Ed.Engl., 53, 2014
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2MWZ
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2N3M
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2MS9
 | | Solution structure of a G-quadruplex | | 分子名称: | DNA (28-MER) | | 著者 | Chung, W.J, Heddi, B, Schmitt, E, Lim, K.W, Mechulam, Y, Phan, A.T. | | 登録日 | 2014-07-25 | | 公開日 | 2015-02-18 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a left-handed DNA G-quadruplex
Proc.Natl.Acad.Sci.USA, 2015
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2LPW
 | | human CEB25 minisatellite G-quadruplex | | 分子名称: | DNA (26-MER) | | 著者 | Amrane, S, Adrian, M, Heddi, B, Serero, A, Nicolas, A, Mergny, J.L, Phan, A.T. | | 登録日 | 2012-02-20 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Formation of Pearl-Necklace Monomorphic G-Quadruplexes in the Human CEB25 Minisatellite.
J.Am.Chem.Soc., 134, 2012
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4U5M
 | | Structure of a left-handed DNA G-quadruplex | | 分子名称: | DNA (28-MER), MAGNESIUM ION, POTASSIUM ION | | 著者 | Schmitt, E, Mechulam, Y, Phan, A.T, Brahim, H, Chung, W.J, Lim, K.W. | | 登録日 | 2014-07-25 | | 公開日 | 2015-02-25 | | 最終更新日 | 2015-03-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a left-handed DNA G-quadruplex.
Proc.Natl.Acad.Sci.USA, 112, 2015
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