7KVB
| Chimeric flavivirus between Binjari virus and Murray Valley encephalitis virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, Matrix protein M | Authors: | Hardy, J.M, Venugopal, H.V, Newton, N.D, Watterson, D, Coulibaly, F.J. | Deposit date: | 2020-11-27 | Release date: | 2020-12-23 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses. Nat Commun, 12, 2021
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6XGR
| YSD1 major tail protein | Descriptor: | YSD1_22 major tail protein | Authors: | Hardy, J.M, Dunstan, R, Venugopal, H, Lithgow, T.J, Coulibaly, F.J. | Deposit date: | 2020-06-17 | Release date: | 2020-07-01 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The architecture and stabilisation of flagellotropic tailed bacteriophages. Nat Commun, 11, 2020
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6XGQ
| YSD1 bacteriophage capsid | Descriptor: | YSD1_16, YSD1_17 | Authors: | Hardy, J.M, Dunstan, R, Venugopal, H, Lithgow, T.J, Coulibaly, F.J. | Deposit date: | 2020-06-17 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | The architecture and stabilisation of flagellotropic tailed bacteriophages. Nat Commun, 11, 2020
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7KV9
| Chimeric flavivirus between Binjari virus and West Nile (Kunjin) virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Matrix protein M, envelope protein E | Authors: | Hardy, J.M, Venugopal, H.V, Newton, N.D, Watterson, D, Coulibaly, F.J. | Deposit date: | 2020-11-27 | Release date: | 2020-12-23 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses. Nat Commun, 12, 2021
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7KV8
| Chimeric flavivirus between Binjari virus and Dengue virus serotype-2 | Descriptor: | (2S,3R,4Z)-3-hydroxy-2-[(9E)-octadec-9-enoylamino]octadec-4-en-1-yl dihydrogen phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | Authors: | Hardy, J.M, Venugopal, H.V, Newton, N.D, Watterson, D, Coulibaly, F.J. | Deposit date: | 2020-11-27 | Release date: | 2020-12-23 | Last modified: | 2021-11-24 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses. Nat Commun, 12, 2021
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7KVA
| Structure of West Nile virus (Kunjin) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, Matrix protein M | Authors: | Hardy, J.M, Venugopal, H.V, Newton, N.D, Watterson, D, Coulibaly, F.J. | Deposit date: | 2020-11-27 | Release date: | 2020-12-23 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses. Nat Commun, 12, 2021
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6XGP
| YSD1_17 major capsid protein | Descriptor: | YSD1_17 major capsid protein | Authors: | Grinter, R, Hardy, J.M, Dunstan, R, Lithgow, T.J, Coulibaly, F.J. | Deposit date: | 2020-06-17 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The architecture and stabilisation of flagellotropic tailed bacteriophages. Nat Commun, 11, 2020
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7L30
| Binjari virus (BinJV) | Descriptor: | Envelope protein E, prM protein | Authors: | Hardy, J.M, Venugopal, H.V, Newton, N.D, Watterson, D, Coulibaly, F.J. | Deposit date: | 2020-12-17 | Release date: | 2021-03-10 | Last modified: | 2021-05-26 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The structure of an infectious immature flavivirus redefines viral architecture and maturation. Sci Adv, 7, 2021
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8U18
| Cryo-EM structure of murine Thrombopoietin receptor ectodomain in complex with Tpo | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombopoietin, Thrombopoietin receptor,GCN4 isoform 1, ... | Authors: | Sarson-Lawrence, K.S, Hardy, J.M, Leis, A, Babon, J.J, Kershaw, N.J. | Deposit date: | 2023-08-30 | Release date: | 2024-02-07 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin. Nat Commun, 15, 2024
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8DGN
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8DGM
| 14-3-3 epsilon bound to phosphorylated PEAK1 (pT1165) peptide | Descriptor: | 1,2-ETHANEDIOL, 14-3-3 protein epsilon, Inactive tyrosine-protein kinase PEAK1 | Authors: | Roy, M.J, Hardy, J.M, Lucet, I.S. | Deposit date: | 2022-06-24 | Release date: | 2023-06-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling. Nat Commun, 14, 2023
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8DGO
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8DGP
| 14-3-3 epsilon bound to phosphorylated PEAK3 (pS69) peptide | Descriptor: | 1,2-ETHANEDIOL, 14-3-3 protein epsilon, Phosphorylated PEAK3 (pS69) peptide, ... | Authors: | Roy, M.J, Hardy, J.M, Lucet, I.S. | Deposit date: | 2022-06-24 | Release date: | 2023-06-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling. Nat Commun, 14, 2023
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5VXR
| The antigen-binding fragment of MAb24 in complex with a peptide from Hepatitis C Virus E2 epitope I (412-423) | Descriptor: | GLYCEROL, MAb24 Variable Heavy Chain,MAb24 Variable Heavy Chain, MAb24 Variable Light Chain,MAb24 Variable Light Chain, ... | Authors: | Hardy, J.M, Gu, J, Boo, I, Drummer, H.E, Coulibaly, F.J. | Deposit date: | 2017-05-24 | Release date: | 2018-02-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes. J. Virol., 92, 2018
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5J36
| Crystal structure of 60-mer BFDV Capsid Protein | Descriptor: | Beak and feather disease virus capsid protein, PHOSPHATE ION | Authors: | Sarker, S, Raidal, S, Aragao, D, Forwood, J.K. | Deposit date: | 2016-03-30 | Release date: | 2016-05-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural insights into the assembly and regulation of distinct viral capsid complexes. Nat Commun, 7, 2016
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5J09
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5J37
| Crystal structure of 60-mer BFDV Capsid Protein in complex with single stranded DNA | Descriptor: | Beak and feather disease virus capsid protein, PHOSPHATE ION, single stranded DNA | Authors: | Sarker, S, Raidal, S, Aragao, D, Forwood, J.K. | Deposit date: | 2016-03-30 | Release date: | 2016-05-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural insights into the assembly and regulation of distinct viral capsid complexes. Nat Commun, 7, 2016
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7KXW
| Crystal structure of DCLK1-KD in complex with DCLK1-IN-1 | Descriptor: | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5-(2,2,2-trifluoroethyl)-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, DI(HYDROXYETHYL)ETHER, Serine/threonine-protein kinase DCLK1, ... | Authors: | Patel, O, Lucet, I. | Deposit date: | 2020-12-05 | Release date: | 2021-09-22 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1. Commun Biol, 4, 2021
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7KX8
| Crystal structure of DCLK1-Cter in complex with FMF-03-055-1 | Descriptor: | 5-ethyl-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Serine/threonine-protein kinase DCLK1 | Authors: | Patel, O, Lucet, I. | Deposit date: | 2020-12-03 | Release date: | 2021-09-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1. Commun Biol, 4, 2021
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7KX6
| Crystal structure of DCLK1-KD in complex with XMD8-85 | Descriptor: | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Serine/threonine-protein kinase DCLK1 | Authors: | Patel, O, Lucet, I. | Deposit date: | 2020-12-03 | Release date: | 2021-09-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1. Commun Biol, 4, 2021
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